Publications by authors named "Jeff O Connell"

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cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions.
Eric Van Buren, Yi Zhang, Xihao Li, Margaret Sunitha Selvaraj, Zilin Li, Jeff O'Connell

Nat Methods· December 2025

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A methodology for gene level omics-WAS integration identifies genes influencing traits associated with cardiovascular risks: the Long Life Family Study.
Sandeep Acharya, Shu Liao, Wooseok J Jung, Yu S Kang, Vaha Akbary Moghaddam, Jeff O Connell

Hum Genet· October 2024

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Multi-omics Integration Identifies Genes Influencing Traits Associated with Cardiovascular Risks: The Long Life Family Study.
Sandeep Acharya, Shu Liao, Wooseok J Jung, Yu S Kang, Vaha A Moghaddam, Jeff O Connell

medRxiv· March 2024

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Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed.
Margaret A Taub, Matthew P Conomos, Rebecca Keener, Kruthika R Iyer, Joshua S Weinstock, Jeff O'Connell

Cell Genom· January 2022

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Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure.
Heming Wang, Raymond Noordam, Brian E Cade, Karen Schwander, Thomas W Winkler, Jeff O'Connell

Mol Psychiatry· November 2021

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Publisher Correction: A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids.
Min-A Jhun, Michael Mendelson, Rory Wilson, Rahul Gondalia, Roby Joehanes, Jeff R O'Connell

Nat Commun· July 2021

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Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.
Lisa de las Fuentes, Yun Ju Sung, Raymond Noordam, Thomas Winkler, Mary F Feitosa, John Connell, Jeff O'Connell

Mol Psychiatry· June 2021

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A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids.
Min-A Jhun, Michael Mendelson, Rory Wilson, Rahul Gondalia, Roby Joehanes, Jeff R O'Connell

Nat Commun· June 2021

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Genetic versus stress and mood determinants of sleep in the Amish.
Heather A Bruce, Peter Kochunov, Joshua Chiappelli, Anya Savransky, Kathleen Carino, Jeff O'Connell

Am J Med Genet B Neuropsychiatr Genet· March 2021

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Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.
Vasiliki Lagou, Reedik Mägi, Jouke- Jan Hottenga, Harald Grallert, John R B Perry, Jeff R O'Connell

Nat Commun· February 2021

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Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.
Vasiliki Lagou, Reedik Mägi, Jouke- Jan Hottenga, Harald Grallert, John R B Perry, Jeff R O'Connell

Nat Commun· January 2021

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Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits.
Daokun Sun, Melissa Richard, Solomon K Musani, Yun Ju Sung, Thomas W Winkler, Jeff R O'Connell

HGG Adv· January 2021

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A lipidome-wide association study of the lipoprotein insulin resistance index.
Minoo Bagheri, Hemant K Tiwari, Anarina L Murillo, Rafet Al-Tobasei, Donna K Arnett, Jeff O'connell

Lipids Health Dis· June 2020

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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.
Ioanna Ntalla, Lu-Chen Weng, James H Cartwright, Amelia Weber Hall, Gardar Sveinbjornsson, Jeff R O'Connell

Nat Commun· May 2020

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Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.
Raymond Noordam, Maxime M Bos, Heming Wang, Thomas W Winkler, Amy R Bentley, Jeff O'Connell

Nat Commun· November 2019

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A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
Yun Ju Sung, Lisa de las Fuentes, Thomas W Winkler, Daniel I Chasman, Amy R Bentley, John M Connell, Jeff R O'Connell

Hum Mol Genet· August 2019

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Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
Paul S de Vries, Michael R Brown, Amy R Bentley, Yun J Sung, Thomas W Winkler, John M Connell, Jeff R O'Connell

Am J Epidemiol· June 2019

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Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
Mary F Feitosa, Aldi T Kraja, Daniel I Chasman, Yun J Sung, Thomas W Winkler, John M Connell, Jeff R O'Connell

PLoS One· January 2019

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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
Tuomas O Kilpeläinen, Amy R Bentley, Raymond Noordam, Yun Ju Sung, Karen Schwander, John Connell, Jeff O'Connell

Nat Commun· January 2019

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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
Symen Ligthart, Ahmad Vaez, Urmo Võsa, Maria G Stathopoulou, Paul S de Vries, Jeff R O'Connell

Am J Hum Genet· November 2018

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A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
Yun J Sung, Thomas W Winkler, Lisa de las Fuentes, Amy R Bentley, Michael R Brown, John M Connell, Jeff R O'Connell

Am J Hum Genet· March 2018

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Heritability of plasma neopterin levels in the Old Order Amish.
Uttam K Raheja, Dietmar Fuchs, Christopher A Lowry, Sarah H Stephens, Mary A Pavlovich, Jeff O'Connell

J Neuroimmunol· June 2017

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Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci.
Geoffrey A Walford, Stefan Gustafsson, Denis Rybin, Alena Stančáková, Han Chen, Jeff R O'Connell

Diabetes· October 2016

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Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN).
Mary K Wojczynski, Laurence D Parnell, Toni I Pollin, Chao Q Lai, Mary F Feitosa, Jeff R O'Connell

Metabolism· October 2015

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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Alisa K Manning, Marie-France Hivert, Robert A Scott, Jonna L Grimsby, Nabila Bouatia-Naji, Jeff O'Connell

Nat Genet· May 2012

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