Publications by authors named "Jeffrey Clarke"

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Updated Overall Survival Analysis From the Phase II PHAROS Study of Encorafenib Plus Binimetinib in Patients With BRAF V600E-Mutant Metastatic Non-Small Cell Lung Cancer.
Melissa L Johnson, Egbert F Smit, Enriqueta Felip, Suresh S Ramalingam, Myung-Ju Ahn, Jeffrey M Clarke

J Clin Oncol· December 2025

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A Phase II study of GT103 in combination with pembrolizumab in refractory, metastatic non-small cell lung cancer.
Hirva Mamdani, Ryan D Gentzler, Lin Gu, Alberto A Chiappori, Frank D Weinberg, Jeffrey Clarke

Cancer· November 2025

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Updated Efficacy and Safety From the Phase 2 PHAROS Study of Encorafenib Plus Binimetinib in Patients With BRAF V600E-Mutant Metastatic NSCLC-A Brief Report.
Gregory J Riely, Myung-Ju Ahn, Jeffrey M Clarke, Ibiayi Dagogo-Jack, Raymond Esper

J Thorac Oncol· October 2025

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Poziotinib for EGFR exon 20-insertion NSCLC: Clinical efficacy of the phase 2 ZENITH trial and differential impact of EGFR exon 20 insertion location on sensitivity.
Xiuning Le, Jacqulyne P Robichaux, Monique Nilsson, R S K Vijayan, Ashwin Ravichandran, Jeffrey M Clarke

Nat Commun· September 2025

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Neoadjuvant, Perioperative, and Adjuvant Immunotherapy in Early-Stage Surgically Resectable Non-Small Cell Lung Cancer: Updates and Future Perspectives.
Diamone Gathers, Cameron Oswalt, Laura Alder, Kevin Chen, Jordyn P Higgins, Jeffrey M Clarke

Cancers (Basel)· June 2025

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Symptomatic Necrosis With Dual Immune-Checkpoint Inhibition and Radiosurgery for Brain Metastases.
Eugene J Vaios, Rachel F Shenker, Peter G Hendrickson, Zihan Wan, Donna Niedzwiecki, Jeffrey M Clarke

JAMA Netw Open· April 2025

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Practical management of adverse events in patients receiving tarlatamab, a delta-like ligand 3-targeted bispecific T-cell engager immunotherapy, for previously treated small cell lung cancer.
Jacob M Sands, Stéphane Champiat, Horst-Dieter Hummel, Kelly G Paulson, Hossein Borghaei, Jeffrey M Clarke

Cancer· February 2025

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Complement factor H targeting antibody GT103 in refractory non-small cell lung cancer: a phase 1b dose escalation trial.
Jeffrey M Clarke, George R Simon, Hirva Mamdani, Lin Gu, James E Herndon

Nat Commun· January 2025

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T-cell Responses to Individualized Neoantigen Therapy mRNA-4157 (V940) Alone or in Combination with Pembrolizumab in the Phase 1 KEYNOTE-603 Study.
Justin F Gainor, Manish R Patel, Jeffrey S Weber, Martin Gutierrez, Julie E Bauman, Jeffrey M Clarke

Cancer Discov· November 2024

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Neighborhood-level socioeconomic disparities in Radon testing in North Carolina from 2010 to 2020.
Zhenchun Yang, Lauren Prox, Clare Meernik, Yadurshini Raveendran, Phillip Gibson, Jeffrey Clarke

J Environ Radioact· July 2024

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Differences in microenvironment of lung cancer and pleural effusions by single-cell RNA sequencing.
Kamran Mahmood, Huimin Wang, Zhicheng Ji, Coral X Giovacchini, Momen M Wahidi, Jeffrey M Clarke

Lung Cancer· July 2024

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A plain language summary of the PHAROS study: the combination of encorafenib and binimetinib for people with BRAF V600E-mutant metastatic non-small-cell lung cancer.
Gregory J Riely, Egbert F Smit, Myung-Ju Ahn, Enriqueta Felip, Suresh S Ramalingam, Jeffrey Clarke

Future Oncol· June 2024

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Identifying MAGE-A4-positive tumors for TCR T cell therapies in HLA-A∗02-eligible patients.
Tianjiao Wang, Jean-Marc Navenot, Stavros Rafail, Cynthia Kurtis, Mark Carroll, Jeffrey M Clarke

Mol Ther Methods Clin Dev· June 2024

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Long-Term Intracranial Outcomes With Combination Dual Immune-Checkpoint Blockade and Stereotactic Radiosurgery in Patients With Melanoma and Non-Small Cell Lung Cancer Brain Metastases.
Eugene J Vaios, Rachel F Shenker, Peter G Hendrickson, Zihan Wan, Donna Niedzwiecki, Jeffrey M Clarke

Int J Radiat Oncol Biol Phys· April 2024

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Unique genomic alterations in the circulating tumor DNA of patients with solid tumors brain metastases.
Laura Alder, Gloria Broadwater, Michelle Green, Amanda E D Van Swearingen, Eric S Lipp, Jeffrey Melson Clarke

Neurooncol Adv· April 2024

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Dose-Limiting Pulmonary Toxicity in a Phase 1/2 Study of Radiation and Chemotherapy with Ipilimumab Followed by Nivolumab for Patients With Stage 3 Unresectable Non-Small Cell Lung Cancer.
Casey L Liveringhouse, Kujtim Latifi, Amalin G Asous, Nghi B Lam, Stephen A Rosenberg, Jeffrey Clarke

Int J Radiat Oncol Biol Phys· July 2023

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High Yield of Pleural Cell-Free DNA for Diagnosis of Oncogenic Mutations in Lung Adenocarcinoma.
Kamran Mahmood, Parvathi Jampani, Jeffrey M Clarke, Steven Wolf, Xiaofei Wang

Chest· July 2023

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Phase II, Open-Label Study of Encorafenib Plus Binimetinib in Patients With -Mutant Metastatic Non-Small-Cell Lung Cancer.
Gregory J Riely, Egbert F Smit, Myung-Ju Ahn, Enriqueta Felip, Suresh S Ramalingam, Jeffrey Clarke

J Clin Oncol· July 2023

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Socioeconomic disparities in immunotherapy use among advanced-stage non-small cell lung cancer patients: analysis of the National Cancer Database.
Anjali Gupta, Chioma Omeogu, Jessica Y Islam, Ashwini Joshi, Dongyu Zhang, Jeffrey M Clarke

Sci Rep· May 2023

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Accuracy and clinical relevance of an automated, algorithm-based analysis of facial signs from selfie images of women in the United States of various ages, ancestries and phototypes: A cross-sectional observational study.
Frederic Flament, Ruowei Jiang, Jeff Houghton, Yuze Zhang, Camille Kroely, Jeffrey Clarke

J Eur Acad Dermatol Venereol· January 2023

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Patient-Reported Distress and Clinical Outcomes with Immuno-Oncology Agents in Metastatic Non-Small Cell Lung Cancer (mNSCLC): A Real-World Retrospective Cohort Study.
Monica H Bodd, Susan C Locke, Steve P Wolf, Scott Antonia, Jeffrey Crawford, Jeffrey M Clarke

Lung Cancer· January 2023

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Autologous T cell therapy for MAGE-A4 solid cancers in HLA-A*02 patients: a phase 1 trial.
David S Hong, Brian A Van Tine, Swethajit Biswas, Cheryl McAlpine, Melissa L Johnson, Jeffrey M Clarke

Nat Med· January 2023

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A Phase 2 Clinical Trial of Combination Nivolumab, Ipilimumab, and Paclitaxel in Patients With Untreated Metastatic NSCLC: The OPTIMAL Trial.
Jeffrey M Clarke, Lin Gu, Xiaofei F Wang, Thomas E Stinchcombe, Marvaretta M Stevenson

JTO Clin Res Rep· June 2022

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Poziotinib in Non-Small-Cell Lung Cancer Harboring Exon 20 Insertion Mutations After Prior Therapies: ZENITH20-2 Trial.
Xiuning Le, Robin Cornelissen, Marina Garassino, Jeffrey M Clarke, Nishan Tchekmedyian

J Clin Oncol· March 2022

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A Need for More Molecular Profiling in Brain Metastases.
Erica Shen, Amanda E D Van Swearingen, Meghan J Price, Ketan Bulsara, Roeland G W Verhaak, Jeffrey M Clarke

Front Oncol· January 2022

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