Publications by authors named "Jeffrey D Rudolf"

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Discovery of a plant-like tridomain bifunctional -abieta-7,13-diene synthase in .
Caitlin A McCadden, Diana P Łomowska-Keehner, Tracy Qu, Jordan Nafie, Tyler A Alsup, Jeffrey D Rudolf

Org Biomol Chem· November 2025

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Discovery of bacterial terpenoids by genome mining.
Wenbo Ning, Jeffrey D Rudolf

Methods Enzymol· July 2025

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Crystal Structure and Catalytic Mechanism of the cis-Eunicellane Cyclase AriE.
Fang-Ru Li, Qian Yang, Jingyi He, Xinru Sun, Xingming Pan, Jeffrey D Rudolf

Chemistry· June 2025

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Avoidance of Secondary Carbocations, Unusual Deprotonation, and Nonstatistical Dynamic Effects in the Cyclization Mechanism of Tetraisoquinane.
Xiuting Wei, William DeSnoo, Zining Li, Wenbo Ning, Wang-Yeuk Kong, Jeffrey D Rudolf

J Am Chem Soc· May 2025

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Exploring and expanding the natural chemical space of bacterial diterpenes.
Xiuting Wei, Wenbo Ning, Caitlin A McCadden, Tyler A Alsup, Zining Li, Jeffrey D Rudolf

Nat Commun· April 2025

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Biosynthesis of a bacterial meroterpenoid reveals a non-canonical class II meroterpenoid cyclase.
Zengyuan Wang, Tyler A Alsup, Xingming Pan, Lu-Lu Li, Jupeng Tian, Jeffrey D Rudolf

Chem Sci· December 2024

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Canonical terpene synthases in arthropods: Intraphylum gene transfer.
Xinlu Chen, John M Urban, Jens Wurlitzer, Xiuting Wei, Jin Han, Jeffrey D Rudolf

Proc Natl Acad Sci U S A· December 2024

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Biocatalytic diversification of abietic acid in Streptomyces.
Caitlin A McCadden, Tyler A Alsup, Ion Ghiviriga, Jeffrey D Rudolf

J Ind Microbiol Biotechnol· December 2024

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Chemical Diversity of Aspergillus alliaceus Phenotypes: Discovery of Brominated Bianthrones with Activity against Triple-Negative Breast Cancer Cell Lines.
Paige E Mandelare, Samantha S Yee, Daniel G Icenhour, Elizabeth N Kaweesa, Mark McCauley, Jeffrey D Rudolf

Chembiochem· October 2024

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Young investigators in natural products chemistry, biosynthesis, and enzymology.
Jeffrey D Rudolf, Lena Barra, Takayoshi Awakawa

Beilstein J Org Chem· October 2024

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Early-stage biosynthesis of phenalinolactone diterpenoids involves sequential prenylation, epoxidation, and cyclization.
Tyler A Alsup, Zining Li, Caitlin A McCadden, Annika Jagels, Diana P Łomowska-Keehner, Jeffrey D Rudolf

RSC Chem Biol· August 2024

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Computation-guided scaffold exploration of 2,6-1,10-eunicellanes.
Zining Li, Sana Jindani, Volga Kojasoy, Teresa Ortega, Erin M Marshall, Jeffrey D Rudolf

Beilstein J Org Chem· June 2024

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Characterization of UbiA terpene synthases with a precursor overproduction system in Escherichia coli.
Tyler A Alsup, Melvin Osei Opoku, Jeffrey D Rudolf

Methods Enzymol· June 2024

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Class II terpene cyclases: structures, mechanisms, and engineering.
Xingming Pan, Jeffrey D Rudolf, Liao-Bin Dong

Nat Prod Rep· March 2024

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Pyrazinone Biosynthesis and Signaling-Myxo Style.
Jeffrey D Rudolf, Sandra Loesgen

ACS Cent Sci· March 2024

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Development of platensimycin, platencin, and platensilin overproducers by biosynthetic pathway engineering and fermentation medium optimization.
Lucas L Fluegel, Ming-Rong Deng, Ping Su, Edward Kalkreuter, Dong Yang, Jeffrey D Rudolf

J Ind Microbiol Biotechnol· January 2024

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Cytochrome P450 Mediated Cyclization in Eunicellane Derived Diterpenoid Biosynthesis.
Zengyuan Wang, Qian Yang, Jingyi He, Haixin Li, Xingming Pan, Jeffrey D Rudolf

Angew Chem Int Ed Engl· November 2023

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Cryptic Isomerization in Diterpene Biosynthesis and the Restoration of an Evolutionarily Defunct P450.
Zining Li, Baofu Xu, Tyler A Alsup, Xiuting Wei, Wenbo Ning, Jeffrey D Rudolf

J Am Chem Soc· October 2023

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First -eunicellane terpene synthase in bacteria.
Zining Li, Baofu Xu, Volga Kojasoy, Teresa Ortega, Donovon A Adpressa, Jeffrey D Rudolf

Chem· March 2023

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Biosynthesis, enzymology, and future of eunicellane diterpenoids.
Zining Li, Jeffrey D Rudolf

J Ind Microbiol Biotechnol· February 2023

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Characterization and Structural Determination of CmnG-A, the Adenylation Domain That Activates the Nonproteinogenic Amino Acid Capreomycidine in Capreomycin Biosynthesis.
I-Hsuan Chen, Ting Cheng, Yung-Lin Wang, Szu-Jo Huang, Yu-Hsuan Hsiao, Jeffrey D Rudolf

Chembiochem· December 2022

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Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase.
Xingming Pan, Wenyu Du, Xiaowei Zhang, Xiaoxu Lin, Fang-Ru Li, Jeffrey D Rudolf

J Am Chem Soc· December 2022

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Mutation of the eunicellane synthase Bnd4 alters its product profile and expands its prenylation ability.
Baofu Xu, Wenbo Ning, Xiuting Wei, Jeffrey D Rudolf

Org Biomol Chem· November 2022

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Structure-guided product determination of the bacterial type II diterpene synthase Tpn2.
Emma A Stowell, Michelle A Ehrenberger, Ya-Lin Lin, Chin-Yuan Chang, Jeffrey D Rudolf

Commun Chem· November 2022

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A roadmap for the functional annotation of protein families: a community perspective.
Valérie de Crécy-Lagard, Rocio Amorin de Hegedus, Cecilia Arighi, Jill Babor, Alex Bateman, Jeffrey D Rudolf

Database (Oxford)· August 2022

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