Publications by authors named "Jeffrey Simms"

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CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology.
Szu-Chi Liao, Kohei Kano, Sadhna Phanse, Mai Nguyen, Elyssa Margolis, Jeffrey Simms

Sci Adv· November 2025

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The GluA1 cytoplasmic tail regulates intracellular AMPA receptor trafficking and synaptic transmission onto dentate gyrus GABAergic interneurons, gating response to novelty.
Gerardo Leana-Sandoval, Alexis Madrid, Ananth V Kolli, Carlene A Chinn, Matthew A Sandoval, Jeffrey Simms

Mol Psychiatry· November 2025

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Cell-type-directed network-correcting combination therapy for Alzheimer's disease.
Yaqiao Li, Carlota Pereda Serras, Jessica Blumenfeld, Min Xie, Yanxia Hao, Jeffrey Simms

Cell· October 2025

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The GluA1 cytoplasmic tail regulates intracellular AMPA receptor trafficking and synaptic transmission onto dentate gyrus GABAergic interneurons, gating response to novelty.
Gerardo Leana-Sandoval, Ananth V Kolli, Carlene A Chinn, Alexis Madrid, Iris Lo, Jeffrey Simms

bioRxiv· December 2024

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Data-driven discovery of cell-type-directed network-correcting combination therapy for Alzheimer's disease.
Yaqiao Li, Carlota Pereda Serras, Jessica Blumenfeld, Min Xie, Yanxia Hao, Jeffrey Simms

bioRxiv· December 2024

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Sex-specific role for the long noncoding RNA Pnky in mouse behavior.
Parna Saha, Rebecca E Andersen, Sung Jun Hong, Eugene Gil, Jeffrey Simms

Nat Commun· August 2024

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CHCHD2 mutant mice display mitochondrial protein accumulation and disrupted energy metabolism.
Szu-Chi Liao, Kohei Kano, Sadhna Phanse, Mai Nguyen, Elyssa Margolis, Jeffrey Simms

bioRxiv· August 2024

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Sex-specific role for the long noncoding RNA in mouse behavior.
Parna Saha, Rebecca E Andersen, Sung Jun Hong, Eugene Gil, Jeffrey Simms

bioRxiv· December 2023

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Closing the Gender Gap in Healthcare Leadership: Can Administrative Fellowships Play a Role?
Julie Robbins, Brooke Z Graham, Andrew N Garman, Randa Smith Hall, Jeffrey Simms

J Healthc Manag· November 2022

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K1.1 preserves the neural stem cell pool and facilitates neuron maturation during adult hippocampal neurogenesis.
Yuan-Hung Lin King, Chao Chen, John V Lin King, Jeffrey Simms, Edward Glasscock

Proc Natl Acad Sci U S A· May 2022

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TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model.
Eric Shao, Che-Wei Chang, Zhiyong Li, Xinxing Yu, Kaitlyn Ho, Jeffrey Simms

Sci Transl Med· April 2022

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Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome.
Annie Arguello, René Meisner, Elliot R Thomsen, Hoang N Nguyen, Ritesh Ravi, Jeffrey Simms

JCI Insight· October 2021

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Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit.
Javier Díaz-Alonso, Wade Morishita, Salvatore Incontro, Jeffrey Simms, Julia Holtzman

Elife· August 2020

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GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models.
Jesse E Hanson, Keran Ma, Justin Elstrott, Martin Weber, Sandrine Saillet, Jeffrey Simms

Cell Rep· January 2020

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TMEM16B Calcium-Activated Chloride Channels Regulate Action Potential Firing in Lateral Septum and Aggression in Male Mice.
Lynn Wang, Jeffrey Simms, Christian J Peters, Marena Tynan-La Fontaine, Kexin Li

J Neurosci· September 2019

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TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala.
Ke-Xin Li, Mu He, Wenlei Ye, Jeffrey Simms, Michael Gill

Elife· September 2019

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Istradefylline reduces memory deficits in aging mice with amyloid pathology.
Anna G Orr, Iris Lo, Heike Schumacher, Kaitlyn Ho, Michael Gill, Jeffrey Simms

Neurobiol Dis· February 2018

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A single alcohol drinking session is sufficient to enable subsequent aversion-resistant consumption in mice.
Kelly Lei, Scott A Wegner, Ji-Hwan Yu, Jeffrey A Simms, F Woodward Hopf

Alcohol· September 2016

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D-Serine and D-Cycloserine Reduce Compulsive Alcohol Intake in Rats.
Taban Seif, Jeffrey A Simms, Kelly Lei, Scott Wegner, Antonello Bonci

Neuropsychopharmacology· September 2015

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Fischer rats consume 20% ethanol in a long-term intermittent-access two-bottle-choice paradigm.
Douglas J Mill, Jade J Bito-Onon, Jeffrey A Simms, Rui Li, Selena E Bartlett

PLoS One· August 2014

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Intermittent access ethanol consumption dysregulates CRF function in the hypothalamus and is attenuated by the CRF-R1 antagonist, CP-376395.
Jeffrey A Simms, Carsten K Nielsen, Rui Li, Selena E Bartlett

Addict Biol· July 2014

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Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake.
Taban Seif, Shao-Ju Chang, Jeffrey A Simms, Stuart L Gibb, Jahan Dadgar

Nat Neurosci· August 2013

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The dual orexin/hypocretin receptor antagonist, almorexant, in the ventral tegmental area attenuates ethanol self-administration.
Subhashini Srinivasan, Jeffrey A Simms, Carsten K Nielsen, Steven P Lieske, Jade J Bito-Onon

PLoS One· March 2013

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Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptors.
Allison A Feduccia, Yuanyuan Wang, Jeffrey A Simms, Henry Y Yi, Rui Li

Pharmacol Biochem Behav· August 2012

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δ-opioid receptor function in the dorsal striatum plays a role in high levels of ethanol consumption in rats.
Carsten K Nielsen, Jeffrey A Simms, Rui Li, Douglas Mill, Henry Yi

J Neurosci· March 2012

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