Publications by authors named "Jen Jen Yeh"

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Cross-platform comparison of gene expression-based cancer molecular subtyping reveals discrepancies with exome capture methods.
Jaewon J Lee, Mohammed Aldakkak, Ashley B Morrison, Sam Z Thalji, Xianlu L Peng, Jen Jen Yeh

NPJ Precis Oncol· December 2025

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S3R: Modeling spatially varying associations with Spatially Smooth Sparse Regression.
Xinyu Zhou, Pengtao Dang, Xiao Wang, Laura Xianlu Peng, Jen Jen Yeh

bioRxiv· November 2025

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PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer.
Gilles Rademaker, Grace A Hernandez, Yurim Seo, Sumena Dahal, Lisa Miller-Phillips, Jen Jen Yeh

Nature· July 2025

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Pan-cancer immune and stromal deconvolution predicts clinical outcomes and mutation profiles.
Bhavneet Bhinder, Verena Friedl, Sunantha Sethuraman, Davide Risso, Kami E Chiotti, Jen Jen Yeh

Sci Rep· July 2025

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New Onset Diabetes in Pancreatic Adenocarcinoma Does Not Correlate With Molecular Subtype.
Hannah E Trembath, Michelle E LaBella, Joseph F Kearney, Arthi Hariharan, Sandra Zarmer, Jen Jen Yeh

J Surg Oncol· May 2025

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Efficient Computation of High-Dimensional Penalized Piecewise Constant Hazard Random Effects Models.
Hillary M Heiling, Naim U Rashid, Quefeng Li, Xianlu L Peng, Jen Jen Yeh

Stat Med· March 2025

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Tumor-Intrinsic Kinome Landscape of Pancreatic Cancer Reveals New Therapeutic Approaches.
Yi Xu, Xianlu L Peng, Michael P East, Ian C McCabe, Grace C Stroman, Jen Jen Yeh

Cancer Discov· February 2025

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Purity Independent Subtyping of Tumors (PurIST) Pancreatic Cancer Classifier: Analytic Validation of a 16-RNA Expression Signature Distinguishing Basal and Classical Subtypes.
Yan Li, Jason D Merker, Rachana Kshatriya, Dimitri G Trembath, Ashley B Morrison, Jen Jen Yeh

J Mol Diagn· November 2024

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CAFomics: convergence to translation for precision stroma approaches.
Ian C McCabe, Xianlu L Peng, Joseph F Kearney, Jen Jen Yeh

Carcinogenesis· November 2024

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Tumor-intrinsic and Cancer-associated Fibroblast Subtypes Independently Predict Outcomes in Pancreatic Cancer.
Jaewon J Lee, Joseph F Kearney, Hannah E Trembath, Arthi Hariharan, Michelle E LaBella, Jen Jen Yeh

Ann Surg· October 2024

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Updates in Molecular Profiling of Pancreatic Ductal Adenocarcinoma.
Jaewon James Lee, Jen Jen Yeh

Surg Clin North Am· October 2024

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Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome.
Michael P East, Robert W Sprung, Denis O Okumu, J Felix Olivares-Quintero, Chinmaya U Joisa, Jen Jen Yeh

bioRxiv· October 2024

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Future of Dendritic Cell-Based Approaches in Pancreatic Cancer.
Ashwin Somasundaram, Jen Jen Yeh

J Clin Oncol· September 2024

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Kinome state is predictive of cell viability in pancreatic cancer tumor and cancer-associated fibroblast cell lines.
Matthew E Berginski, Madison R Jenner, Chinmaya U Joisa, Gabriela Herrera Loeza, Brian T Golitz, Jen Jen Yeh

PeerJ· September 2024

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nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer.
Audrey M Hendley, Sudipta Ashe, Atsushi Urano, Martin Ng, Tuan Anh Phu, Jen Jen Yeh

bioRxiv· September 2024

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Pan-lysyl oxidase inhibition disrupts fibroinflammatory tumor stroma, rendering cholangiocarcinoma susceptible to chemotherapy.
Paul R Burchard, Luis I Ruffolo, Nicholas A Ullman, Benjamin S Dale, Yatee A Dave, Jen Jen Yeh

Hepatol Commun· August 2024

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Gastrointestinal Malignancy: Genetic Implications to Clinical Applications.
Hannah E Trembath, Jen Jen Yeh, Nicole E Lopez

Cancer Treat Res· August 2024

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Determination of permissive and restraining cancer-associated fibroblast (DeCAF) subtypes.
Xianlu Laura Peng, Elena V Kharitonova, Yi Xu, Joseph F Kearney, Changfei Luan, Jen Jen Yeh

bioRxiv· May 2024

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Myofibroblastic cancer-associated fibroblast subtype heterogeneity in pancreatic cancer.
Joseph F Kearney, Hannah E Trembath, Priscilla S Chan, Ashley B Morrison, Yi Xu, Jen Jen Yeh

J Surg Oncol· April 2024

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First-in-Class Humanized Antibody against Alternatively Spliced Tissue Factor Augments Anti-Metastatic Efficacy of Chemotherapy in a Preclinical Model of Pancreatic Ductal Adenocarcinoma.
Clayton S Lewis, Charles Backman, Sabahat Ahsan, Ashley Cliff, Arthi Hariharan, Jen Jen Yeh

Int J Mol Sci· February 2024

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Efficient computation of high-dimensional penalized generalized linear mixed models by latent factor modeling of the random effects.
Hillary M Heiling, Naim U Rashid, Quefeng Li, Xianlu L Peng, Jen Jen Yeh

Biometrics· January 2024

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Integrated single-dose kinome profiling data is predictive of cancer cell line sensitivity to kinase inhibitors.
Chinmaya U Joisa, Kevin A Chen, Matthew E Berginski, Brian T Golitz, Madison R Jenner, Jen Jen Yeh

PeerJ· December 2023

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Identifying patient profiles of disparate care in resectable pancreas cancer using latent class analysis.
Ugwuji N Maduekwe, Briana J K Stephenson, Jen Jen Yeh, Melissa A Troester, Hanna K Sanoff

J Surg Oncol· August 2023

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Sub-Cluster Identification through Semi-Supervised Optimization of Rare-Cell Silhouettes (SCISSORS) in single-cell RNA-sequencing.
Jack R Leary, Yi Xu, Ashley B Morrison, Chong Jin, Emily C Shen, Jen Jen Yeh

Bioinformatics· August 2023

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Promise of bile circulating tumor DNA in biliary tract cancers.
Joseph F Kearney, Deborah Weighill, Jen Jen Yeh

Cancer· June 2023

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