Publications by authors named "Jen-Tsun Lin"

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Quinovic Acid Enhances the Cytotoxicity of KHYG-1 Cells by Modulating the Ras/MAPK Signalling Pathway and Interferon-Gamma Expression.
Ming-Ju Hsieh, Jen-Tsun Lin, Yi-Ching Chuang, Hsin-Yu Ho, Yu-Sheng Lo, Chia-Chieh Lin

J Cell Mol Med· November 2025

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Raddeanin A augments the cytotoxicity of natural killer cells against chronic myeloid leukaemia cells by modulating MAPK and Ras/Raf signalling pathways.
Ming-Ju Hsieh, Jen-Tsun Lin, Yi-Ching Chuang, Yu-Sheng Lo, Chia-Chieh Lin

J Cell Mol Med· August 2024

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Limocitrin increases cytotoxicity of KHYG-1 cells against K562 cells by modulating MAPK pathway.
Ming-Ju Hsieh, Jen-Tsun Lin, Yi-Ching Chuang, Chia-Chieh Lin, Yu-Sheng Lo

Environ Toxicol· December 2023

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Shuterin Enhances the Cytotoxicity of the Natural Killer Leukemia Cell Line KHYG-1 by Increasing the Expression Levels of Granzyme B and IFN-γ through the MAPK and Ras/Raf Signaling Pathways.
Jen-Tsun Lin, Yi-Ching Chuang, Mu-Kuan Chen, Yu-Sheng Lo, Chia-Chieh Lin

Int J Mol Sci· October 2022

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7-Epitaxol Induces Apoptosis and Autophagy in Head and Neck Squamous Cell Carcinoma through Inhibition of the ERK Pathway.
V Bharath Kumar, Ming-Ju Hsieh, B Mahalakshmi, Yi-Ching Chuang, Chia-Chieh Lin, Jen-Tsun Lin

Cells· October 2021

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Dehydrocrenatidine inhibits head and neck cancer cells invasion and migration by modulating JNK1/2 and ERK1/2 pathway and decreases MMP-2 expression.
Bharath Kumar Velmurugan, Jen-Tsun Lin, B Mahalakshmi, Chia-Chieh Lin, Yi-Ching Chuang

Environ Toxicol· September 2021

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Dehydrocrenatidine extracted from induces the apoptosis of nasopharyngeal carcinoma cells through the JNK and ERK signaling pathways.
Ming-Chang Hsieh, Yu-Sheng Lo, Yi-Ching Chuang, Chia-Chieh Lin, Hsin-Yu Ho, Jen-Tsun Lin

Oncol Rep· August 2021

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Pinosylvin inhibits migration and invasion of nasopharyngeal carcinoma cancer cells via regulation of epithelial‑mesenchymal transition and inhibition of MMP‑2.
Yi-Ching Chuang, Ming-Chang Hsieh, Chia-Chieh Lin, Yu-Sheng Lo, Hsin-Yu Ho, Jen-Tsun Lin

Oncol Rep· July 2021

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PlatyphyllenoneExerts Anti-Metastatic Effects on Human Oral Cancer Cells by Modulating Cathepsin L Expression, MAPK Pathway and Epithelial-Mesenchymal Transition.
V Bharath Kumar, Jen-Tsun Lin, B Mahalakshmi, Yi-Ching Chuang, Hsin-Yu Ho, Chia-Chieh Lin

Int J Mol Sci· May 2021

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Antimetastatic Effects of Sesamin on Human Head and Neck Squamous Cell Carcinoma through Regulation of Matrix Metalloproteinase-2.
Jian-Ming Chen, Pei-Yin Chen, Chia-Chieh Lin, Ming-Chang Hsieh, Jen-Tsun Lin

Molecules· May 2020

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Luteolin-7-O-Glucoside Inhibits Oral Cancer Cell Migration and Invasion by Regulating Matrix Metalloproteinase-2 Expression and Extracellular Signal-Regulated Kinase Pathway.
Bharath Kumar Velmurugan, Jen-Tsun Lin, B Mahalakshmi, Yi-Ching Chuang, Chia-Chieh Lin

Biomolecules· March 2020

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Pinosylvin reduced migration and invasion of oral cancer carcinoma by regulating matrix metalloproteinase-2 expression and extracellular signal-regulated kinase pathway.
Mu-Kuan Chen, Yen-Tze Liu, Jen-Tsun Lin, Chia-Chieh Lin, Yi-Ching Chuang

Biomed Pharmacother· September 2019

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Celastrol, a plant-derived triterpene, induces cisplatin-resistance nasopharyngeal carcinoma cancer cell apoptosis though ERK1/2 and p38 MAPK signaling pathway.
Ming-Ju Hsieh, Che-Wei Wang, Jen-Tsun Lin, Yi-Ching Chuang, Yi-Ting Hsi, Chia-Chieh Lin

Phytomedicine· May 2019

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Coronarin D induces human oral cancer cell apoptosis though upregulate JNK1/2 signaling pathway.
Yen-Tze Liu, Ming-Ju Hsieh, Jen-Tsun Lin, Gene Chen, Chia-Chieh Lin

Environ Toxicol· April 2019

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Erianin induces cell apoptosis through ERK pathway in human nasopharyngeal carcinoma.
Yen-Tze Liu, Ming-Ju Hsieh, Jen-Tsun Lin, Gene Chen, Chia-Chieh Lin

Biomed Pharmacother· March 2019

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Polyphyllin G induces apoptosis and autophagy cell death in human oral cancer cells Phytomedicine 23 (2016) 1545-1554.
Ming-Ju Hsieh, Su-Yu Chien, Jen-Tsun Lin, Shun-Fa Yang, Mu-Kuan Chen

Phytomedicine· June 2018

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Is definitive concurrent chemoradiotherapy effective for locally advanced head and neck cancer in the elderly aged ≥ 75 years: A single-institute, retrospective, cohort study.
Kuan-Ming Lai, Jen-Tsun Lin, Hsueh-Ju Lu, Chia-Chun Liang, Mu-Kuan Chen

Asia Pac J Clin Oncol· June 2018

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Functional FGFR4 Gly388Arg polymorphism contributes to oral squamous cell carcinoma susceptibility.
Chia-Hsuan Chou, Ming-Ju Hsieh, Chun-Yi Chuang, Jen-Tsun Lin, Chia-Ming Yeh, Chiao-Wen Lin

Oncotarget· November 2017

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Polyphyllin G induces apoptosis and autophagy cell death in human oral cancer cells.
Ming-Ju Hsieh, Su-Yu Chien, Jen-Tsun Lin, Shun-Fa Yang, Mu-Kuan Chen

Phytomedicine· December 2016

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Polyphyllin G induce apoptosis and autophagy in human nasopharyngeal cancer cells by modulation of AKT and mitogen-activated protein kinase pathways in vitro and in vivo.
Jui-Chieh Chen, Ming-Ju Hsieh, Chih-Jung Chen, Jen-Tsun Lin, Yu-Sheng Lo

Oncotarget· October 2016

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Colon cancer mesenchymal stem cells modulate the tumorigenicity of colon cancer through interleukin 6.
Jen-Tsun Lin, Jeng-Yi Wang, Mu-Kuan Chen, Hong-Chang Chen, Tung-Hao Chang

Exp Cell Res· August 2013

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Chemotherapy with modified docetaxel, cisplatin, and 5-fluorouracil in patients with metastatic head and neck cancer.
Jen-Tsun Lin, Guam-Min Lai, Tung-Hao Chang, Mu-Tai Liu, Chu-Ping Bi

Adv Ther· January 2012

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Association of high levels of Jagged-1 and Notch-1 expression with poor prognosis in head and neck cancer.
Jen-Tsun Lin, Mu-Kuan Chen, Kun-Tu Yeh, Cheng-Shyong Chang, Tung-Hao Chang, Chi-Yon Lin

Ann Surg Oncol· November 2010

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Prognostic value of pretreatment CD44 mRNA in peripheral blood of patients with locally advanced head and neck cancer.
Jen-Tsun Lin, Tung-Hao Chang, Cheng-Shong Chang, Wen-Hong Wang, Bi-Wen Su

Oral Oncol· May 2010

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Docetaxel, carboplatin and 5-fluorouracil (TCF) chemotherapy in patients with unresectable metastatic carcinoma of cervix.
Jen-Tsun Lin, Shen-Chang Shih, Tung-Hao Chang, Cheng-Shong Chang

Gynecol Oncol· April 2010

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