Publications by authors named "Jenifer Bear"

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Highly immunogenic DNA/LION nanocarrier vaccine potently activates lymph nodes inducing long-lasting immunity in macaques.
Sevasti Karaliota, Maha Moussa, Margherita Rosati, Santhi Devasundaram, Soumya Sengupta, Jenifer Bear

iScience· April 2025

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Focusing HIV-1 Gag T cell responses to highly conserved regions by DNA vaccination in HVTN 119.
Spyros A Kalams, Barbara K Felber, James I Mullins, Hyman M Scott, Mary A Allen, Jenifer Bear

JCI Insight· August 2024

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The immunogenicity of an HIV-1 Gag conserved element DNA vaccine in people with HIV and receiving antiretroviral therapy.
Jeffrey M Jacobson, Barbara K Felber, Huichao Chen, George N Pavlakis, James I Mullins, Jenifer Bear

AIDS· June 2024

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Rapid transient and longer-lasting innate cytokine changes associated with adaptive immunity after repeated SARS-CoV-2 BNT162b2 mRNA vaccinations.
Margherita Rosati, Evangelos Terpos, Philip Homan, Cristina Bergamaschi, Sevasti Karaliota, Jenifer Bear

Front Immunol· December 2023

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XBB.1.5 neutralizing antibodies upon bivalent COVID-19 vaccination are similar to XBB but lower than BQ.1.1.
Santhi Devasundaram, Evangelos Terpos, Margherita Rosati, Ioannis Ntanasis-Stathopoulos, Jenifer Bear

Am J Hematol· May 2023

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Step-dose IL-7 treatment promotes systemic expansion of T cells and alters immune cell landscape in blood and lymph nodes.
Hrishikesh Pandit, Antonio Valentin, Matthew Angel, Claire Deleage, Cristina Bergamaschi, Jenifer Bear

iScience· February 2023

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Low Spike Antibody Levels and Impaired BA.4/5 Neutralization in Patients with Multiple Myeloma or Waldenstrom's Macroglobulinemia after BNT162b2 Booster Vaccination.
Margherita Rosati, Evangelos Terpos, Jenifer Bear, Robert Burns, Santhi Devasundaram

Cancers (Basel)· November 2022

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Reduced Antibodies and Innate Cytokine Changes in SARS-CoV-2 BNT162b2 mRNA Vaccinated Transplant Patients With Hematological Malignancies.
Cristina Bergamaschi, Maria Pagoni, Margherita Rosati, Matthew Angel, Ifigeneia Tzannou, Jenifer Bear

Front Immunol· June 2022

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Distinct neutralization profile of spike variants by antibodies induced upon SARS-CoV-2 infection or vaccination.
Margherita Rosati, Evangelos Terpos, Mahesh Agarwal, Vangelis Karalis, Jenifer Bear

Am J Hematol· January 2022

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Sequential Analysis of Binding and Neutralizing Antibody in COVID-19 Convalescent Patients at 14 Months After SARS-CoV-2 Infection.
Margherita Rosati, Evangelos Terpos, Ioannis Ntanasis-Stathopoulos, Mahesh Agarwal, Jenifer Bear

Front Immunol· December 2021

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Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+Protein co-immunization in rhesus macaques.
Margherita Rosati, Mahesh Agarwal, Xintao Hu, Santhi Devasundaram, Dimitris Stellas, Jenifer Bear

PLoS Pathog· September 2021

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Kinetics of Nucleocapsid, Spike and Neutralizing Antibodies, and Viral Load in Patients with Severe COVID-19 Treated with Convalescent Plasma.
Thomas P Thomopoulos, Margherita Rosati, Evangelos Terpos, Dimitris Stellas, Xintao Hu, Jenifer Bear

Viruses· September 2021

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Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients.
Cristina Bergamaschi, Evangelos Terpos, Margherita Rosati, Matthew Angel, Jenifer Bear

Cell Rep· August 2021

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SARS-CoV-2 antibody kinetics eight months from COVID-19 onset: Persistence of spike antibodies but loss of neutralizing antibodies in 24% of convalescent plasma donors.
Evangelos Terpos, Dimitris Stellas, Margherita Rosati, Theodoros N Sergentanis, Xintao Hu, Jenifer Bear

Eur J Intern Med· July 2021

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A Phase II Study on the Use of Convalescent Plasma for the Treatment of Severe COVID-19- A Propensity Score-Matched Control Analysis.
Vasiliki Pappa, Anthi Bouchla, Evangelos Terpos, Thomas P Thomopoulos, Margherita Rosati, Jenifer Bear

Microorganisms· April 2021

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Priming with DNA Expressing Trimeric HIV V1V2 Alters the Immune Hierarchy Favoring the Development of V2-Specific Antibodies in Rhesus Macaques.
Santhi Devasundaram, Margherita Rosati, Antonio Valentin, Svenja Weiss, Vincenza Itri, Jenifer Bear

J Virol· December 2020

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A Prime/Boost Vaccine Regimen Alters the Rectal Microbiome and Impacts Immune Responses and Viremia Control Post-Simian Immunodeficiency Virus Infection in Male and Female Rhesus Macaques.
Thomas Musich, Vishal Thovarai, David J Venzon, Venkatramanan Mohanram, Iskra Tuero, Jenifer Bear

J Virol· November 2020

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Anti-SARS-CoV-2 Antibody Responses in Convalescent Plasma Donors Are Increased in Hospitalized Patients; Subanalyses of a Phase 2 Clinical Study.
Evangelos Terpos, Marianna Politou, Theodoros N Sergentanis, Andreas Mentis, Margherita Rosati, Jenifer Bear

Microorganisms· November 2020

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Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10.
Cristina Bergamaschi, Hrishikesh Pandit, Bethany A Nagy, Dimitris Stellas, Shawn M Jensen, Jenifer Bear

J Immunother Cancer· May 2020

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Molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivity.
Khue G Nguyen, Francis B Gillam, Jared J Hopkins, Srinivas Jayanthi, Ravi Kumar Gundampati, Jenifer Bear

J Biol Chem· March 2019

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Early T Follicular Helper Cell Responses and Germinal Center Reactions Are Associated with Viremia Control in Immunized Rhesus Macaques.
Sabrina Helmold Hait, Diego A Vargas-Inchaustegui, Thomas Musich, Venkatramanan Mohanram, Iskra Tuero, Jenifer Bear

J Virol· February 2019

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Correction: Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes.
Dionysios C Watson, Eirini Moysi, Antonio Valentin, Cristina Bergamaschi, Santhi Devasundaram, Jenifer Bear

PLoS Pathog· October 2018

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Control of Heterologous Simian Immunodeficiency Virus SIV Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques.
Shakti Singh, Eric G Ramírez-Salazar, Rami Doueiri, Antonio Valentin, Margherita Rosati, Jenifer Bear

J Virol· August 2018

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Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes.
Dionysios C Watson, Eirini Moysi, Antonio Valentin, Cristina Bergamaschi, Santhi Devasundaram, Jenifer Bear

PLoS Pathog· February 2018

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Scalable, cGMP-compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL-15/lactadherin complexes.
Dionysios C Watson, Bryant C Yung, Cristina Bergamaschi, Bhabadeb Chowdhury, Jenifer Bear

J Extracell Vesicles· February 2018

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