Publications by authors named "Jennifer Bre"

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A phosphoramidate modification of FUDR, NUC-3373, causes DNA damage and DAMPs release from colorectal cancer cells, potentiating lymphocyte-induced cell death.
Oliver J Read, Jennifer Bré, Ying Zhang, Peter Mullen, Mustafa Elshani

PLoS One· September 2025

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Defining the mode of action of cisplatin combined with NUC-1031, a phosphoramidate modification of gemcitabine.
Dillum Patel, Alison L Dickson, Greice M Zickuhr, In Hwa Um, Oliver J Read

Transl Oncol· December 2024

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The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent.
Jennifer Bré, Alison L Dickson, Oliver J Read, Ying Zhang, Fiona G McKissock

Cancer Chemother Pharmacol· May 2023

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Heparanase-1 is upregulated by hepatitis C virus and favors its replication.
Christophe Gallard, Nadjet Lebsir, Hira Khursheed, Emma Reungoat, Marie-Laure Plissonnier

J Hepatol· July 2022

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Genome-scale CRISPR/Cas9 screen determines factors modulating sensitivity to ProTide NUC-1031.
Awa Sarr, Jennifer Bré, In Hwa Um, Tsz Huen Chan, Peter Mullen

Sci Rep· May 2019

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