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Publications by authors named "Jennifer C Cookson"

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Antitumor polycyclic acridines. 20. Search for DNA quadruplex binding selectivity in a series of 8,13-dimethylquino[4,3,2-kl]acridinium salts: telomere-targeted agents.
Mai-Kim Cheng, Chetna Modi, Jennifer C Cookson, Ian Hutchinson, Robert A Heald

J Med Chem· February 2008


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Pharmacodynamics of the G-quadruplex-stabilizing telomerase inhibitor 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in vitro: activity in human tumor cells correlates with telomere length and can be enhanced, or antagonized, with cytotoxic agents.
Jennifer C Cookson, Fangping Dai, Victoria Smith, Robert A Heald, Charles A Laughton

Mol Pharmacol· December 2005


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Antitumor polycyclic acridines. 17. Synthesis and pharmaceutical profiles of pentacyclic acridinium salts designed to destabilize telomeric integrity.
Jennifer C Cookson, Robert A Heald, Malcolm F G Stevens

J Med Chem· November 2005


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