Publications by authors named "Jennifer Greaves"

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Different chains for different gains: How acyl chain diversity shapes S-acylated protein function.
Carla Busquets Hernández, Alexandra Tsiotsia, Ludovico Pipitò, Luke H Chamberlain, Jennifer Greaves

Prog Lipid Res· November 2025

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S-acylation and neuroinflammation: the therapeutic potential of zDHHC and deacylase modulation.
Tiago A Duarte, Choa P Ng, Jorge A R Salvador, Ludovico Pipito, Jennifer Greaves

Eur J Med Chem· November 2025

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Probing the Interactions of Thiazole Abietane Inhibitors with the Human Serine Hydrolases ABHD16A and ABHD12.
Tiina J Ahonen, Choa P Ng, Beatriz Farinha, Bárbara Almeida, Bruno L Victor, Jennifer Greaves

ACS Med Chem Lett· October 2023

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The Hydrophobic Cysteine-rich Domain of SNAP25 Couples with Downstream Residues to Mediate Membrane Interactions and Recognition by DHHC Palmitoyl Transferases.
Jennifer Greaves, Gerald R Prescott, Yuko Fukata, Masaki Fukata, Christine Salaun

Mol Biol Cell· September 2022

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Deform the membrane, cAPTure the lipid.
Jennifer Greaves

Nat Chem Biol· April 2021

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The linker domain of the SNARE protein SNAP25 acts as a flexible molecular spacer that ensures efficient S-acylation.
Christine Salaun, Jennifer Greaves, Nicholas C O Tomkinson, Luke H Chamberlain

J Biol Chem· May 2020

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Detection of Heterogeneous Protein S-Acylation in Cells.
Jennifer Greaves, Nicholas C O Tomkinson

Methods Mol Biol· March 2020

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Fam49/CYRI interacts with Rac1 and locally suppresses protrusions.
Loic Fort, José Miguel Batista, Peter A Thomason, Heather J Spence, Jamie A Whitelaw, Jennifer Greaves

Nat Cell Biol· October 2018

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S-acylation regulates the trafficking and stability of the unconventional Q-SNARE STX19.
Khamal K Ampah, Jennifer Greaves, Amber S Shun-Shion, Asral W Asnawi, Jessica A Lidster

J Cell Sci· October 2018

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LIF-dependent survival of embryonic stem cells is regulated by a novel palmitoylated Gab1 signalling protein.
Linda Sutherland, Madeleine Ruhe, Daniela Gattegno-Ho, Karanjit Mann, Jennifer Greaves

J Cell Sci· September 2018

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Tracking intracellular uptake and localisation of alkyne tagged fatty acids using Raman spectroscopy.
Lauren E Jamieson, Jennifer Greaves, Jayde A McLellan, Kevin R Munro, Nicholas C O Tomkinson

Spectrochim Acta A Mol Biomol Spectrosc· May 2018

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The C-terminal domain of zDHHC2 contains distinct sorting signals that regulate intracellular localisation in neurons and neuroendocrine cells.
Christine Salaun, Louise Ritchie, Jennifer Greaves, Trevor J Bushell, Luke H Chamberlain

Mol Cell Neurosci· December 2017

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Substrate selectivity in the zDHHC family of -acyltransferases.
Kimon Lemonidis, Christine Salaun, Marianna Kouskou, Cinta Diez-Ardanuy, Luke H Chamberlain, Jennifer Greaves

Biochem Soc Trans· June 2017

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Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry.
Jennifer Greaves, Kevin R Munro, Stuart C Davidson, Matthieu Riviere, Justyna Wojno

Proc Natl Acad Sci U S A· February 2017

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A cluster of palmitoylated cysteines are essential for aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis.
Cinta Diez-Ardanuy, Jennifer Greaves, Kevin R Munro, Nicholas C O Tomkinson, Luke H Chamberlain

Sci Rep· January 2017

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The zDHHC family of S-acyltransferases.
Kimon Lemonidis, Martin W Werno, Jennifer Greaves, Cinta Diez-Ardanuy, Maria C Sanchez-Perez

Biochem Soc Trans· April 2015

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New links between S-acylation and cancer.
Jennifer Greaves, Luke H Chamberlain

J Pathol· May 2014

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Palmitoylation and the trafficking of peripheral membrane proteins.
Luke H Chamberlain, Kimon Lemonidis, Maria Sanchez-Perez, Martin W Werno, Oforiwa A Gorleku, Jennifer Greaves

Biochem Soc Trans· February 2013

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Palmitoylation-induced aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis.
Jennifer Greaves, Kimon Lemonidis, Oforiwa A Gorleku, Carlos Cruchaga, Christopher Grefen

J Biol Chem· October 2012

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Endoplasmic reticulum localization of DHHC palmitoyltransferases mediated by lysine-based sorting signals.
Oforiwa A Gorleku, Anna-Marie Barns, Gerald R Prescott, Jennifer Greaves, Luke H Chamberlain

J Biol Chem· November 2011

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The palmitoyl transferase DHHC2 targets a dynamic membrane cycling pathway: regulation by a C-terminal domain.
Jennifer Greaves, Juliet A Carmichael, Luke H Chamberlain

Mol Biol Cell· June 2011

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DHHC palmitoyl transferases: substrate interactions and (patho)physiology.
Jennifer Greaves, Luke H Chamberlain

Trends Biochem Sci· May 2011

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Differential palmitoylation regulates intracellular patterning of SNAP25.
Jennifer Greaves, Luke H Chamberlain

J Cell Sci· April 2011

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The intracellular dynamic of protein palmitoylation.
Christine Salaun, Jennifer Greaves, Luke H Chamberlain

J Cell Biol· December 2010

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Palmitoylation of the SNAP25 protein family: specificity and regulation by DHHC palmitoyl transferases.
Jennifer Greaves, Oforiwa A Gorleku, Christine Salaun, Luke H Chamberlain

J Biol Chem· August 2010

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