Publications by authors named "Jennifer Irvine"

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Digital tools to promote or measure health literacy in children aged 3-5 years: scoping review.
Caron Molster, Jennifer Irvine, Amanda Devine, Ruth Wallace, Lennie Barblett

Health Promot Int· July 2025

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Nitroxyl (HNO) reduces endothelial and monocyte activation and promotes M2 macrophage polarization.
Karen L Andrews, Amanda K Sampson, Jennifer C Irvine, Waled A Shihata, Danielle L Michell

Clin Sci (Lond)· September 2016

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Compound 21, a selective agonist of angiotensin AT2 receptors, prevents endothelial inflammation and leukocyte adhesion in vitro and in vivo.
Amanda K Sampson, Jennifer C Irvine, Waled A Shihata, Dragana Dragoljevic, Natalie Lumsden

Br J Pharmacol· February 2016

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Raised soluble P-selectin moderately accelerates atherosclerotic plaque progression.
Kevin J Woollard, Natalie G Lumsden, Karen L Andrews, Andrea Aprico, Emma Harris, Jennifer C Irvine

PLoS One· February 2015

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Nitroxyl donors retain their depressor effects in hypertension.
Jennifer C Irvine, Ravina M Ravi, Barbara K Kemp-Harper, Robert E Widdop

Am J Physiol Heart Circ Physiol· September 2013

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HNO/cGMP-dependent antihypertrophic actions of isopropylamine-NONOate in neonatal rat cardiomyocytes: potential therapeutic advantages of HNO over NO.
Jennifer C Irvine, Nga Cao, Swati Gossain, Amy E Alexander, Jane E Love

Am J Physiol Heart Circ Physiol· August 2013

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The soluble guanylyl cyclase activator bay 58-2667 selectively limits cardiomyocyte hypertrophy.
Jennifer C Irvine, Virat Ganthavee, Jane E Love, Amy E Alexander, John D Horowitz

PLoS One· April 2013

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Nitroxyl (HNO) stimulates soluble guanylyl cyclase to suppress cardiomyocyte hypertrophy and superoxide generation.
Eliane Q Lin, Jennifer C Irvine, Anh H Cao, Amy E Alexander, Jane E Love

PLoS One· October 2012

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Nitroxyl (HNO) as a vasoprotective signaling molecule.
Michelle L Bullen, Alyson A Miller, Karen L Andrews, Jennifer C Irvine, Rebecca H Ritchie

Antioxid Redox Signal· May 2011

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Chronic administration of the HNO donor Angeli's salt does not lead to tolerance, cross-tolerance, or endothelial dysfunction: comparison with GTN and DEA/NO.
Jennifer C Irvine, Barbara K Kemp-Harper, Robert E Widdop

Antioxid Redox Signal· May 2011

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Exploiting cGMP-based therapies for the prevention of left ventricular hypertrophy: NO* and beyond.
Rebecca H Ritchie, Jennifer C Irvine, Anke C Rosenkranz, Ruchi Patel, Igor R Wendt

Pharmacol Ther· December 2009

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A role for nitroxyl (HNO) as an endothelium-derived relaxing and hyperpolarizing factor in resistance arteries.
Karen L Andrews, Jennifer C Irvine, Marianne Tare, Jacqueline Apostolopoulos, Joanne L Favaloro

Br J Pharmacol· June 2009

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Nitroxyl (HNO): the Cinderella of the nitric oxide story.
Jennifer C Irvine, Rebecca H Ritchie, Joanne L Favaloro, Karen L Andrews, Robert E Widdop

Trends Pharmacol Sci· December 2008

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Designing better coumarin-based fluorogenic substrates for PTP1B.
Christopher P Holmes, Natalie Macher, J Russell Grove, Larry Jang, Jennifer D Irvine

Bioorg Med Chem Lett· June 2008

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PTP1B inhibitors: synthesis and evaluation of difluoro-methylenephosphonate bioisosteres on a sulfonamide scaffold.
Christopher P Holmes, Xianfeng Li, Yijun Pan, Caiding Xu, Ashok Bhandari, Jennifer D Irvine

Bioorg Med Chem Lett· April 2008

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Nitroxyl anion donor, Angeli's salt, does not develop tolerance in rat isolated aortae.
Jennifer C Irvine, Joanne L Favaloro, Robert E Widdop, Barbara K Kemp-Harper

Hypertension· April 2007

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Discovery and structure-activity relationships of novel sulfonamides as potent PTP1B inhibitors.
Christopher P Holmes, Xianfeng Li, Yijun Pan, Caiding Xu, Ashok Bhandari, Jennifer D Irvine

Bioorg Med Chem Lett· October 2005

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NO- activates soluble guanylate cyclase and Kv channels to vasodilate resistance arteries.
Jennifer C Irvine, Joanne L Favaloro, Barbara K Kemp-Harper

Hypertension· June 2003

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Assay development and high-throughput screening of caspases in microfluidic format.
Ge Wu, Jennifer Irvine, Chris Luft, David Pressley, C Nicholas Hodge

Comb Chem High Throughput Screen· June 2003

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