Publications by authors named "Jennifer M Speth"

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MAPK phosphatase 1 inhibition of p38α within lung myofibroblasts is essential for spontaneous fibrosis resolution.
Sean M Fortier, Natalie M Walker, Loka R Penke, Jared D Baas, Qinxue Shen, Jennifer M Speth

J Clin Invest· March 2024

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GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress.
Weihua Zhou, Zitong Zhao, Angelica Lin, John Z Yang, Jie Xu, Jennifer M Speth

Cancer Discov· January 2024

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KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis.
Loka R Penke, Jennifer M Speth, Steven K Huang, Sean M Fortier, Jared Baas

JCI Insight· August 2022

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PGE accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking.
Loka R Penke, Jennifer M Speth, Christina Draijer, Zbigniew Zaslona, Judy Chen

Life Sci Alliance· November 2020

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Alveolar macrophage-derived extracellular vesicles inhibit endosomal fusion of influenza virus.
Daniel J Schneider, Katherine A Smith, Catrina E Latuszek, Carol A Wilke, Danny M Lyons, Jennifer M Speth

EMBO J· August 2020

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Resident alveolar macrophage-derived vesicular SOCS3 dampens allergic airway inflammation.
Christina Draijer, Jennifer M Speth, Loka R K Penke, Zbigniew Zaslona, Joseph D Bazzill

FASEB J· March 2020

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Transcriptional regulation of the IL-13Rα2 gene in human lung fibroblasts.
Loka R Penke, Hideyasu Ouchi, Jennifer M Speth, Njira Lugogo, Yvonne J Huang

Sci Rep· January 2020

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Alveolar macrophage secretion of vesicular SOCS3 represents a platform for lung cancer therapeutics.
Jennifer M Speth, Loka R Penke, Joseph D Bazzill, Kyung Soo Park, Rafael Gil de Rubio

JCI Insight· October 2019

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FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis.
Loka R Penke, Jennifer M Speth, Vijaya L Dommeti, Eric S White, Ingrid L Bergin

J Clin Invest· June 2018

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Mechanisms and modulation of microvesicle uptake in a model of alveolar cell communication.
Daniel J Schneider, Jennifer M Speth, Loka R Penke, Scott H Wettlaufer, Joel A Swanson

J Biol Chem· December 2017

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Signed, Sealed, Delivered: Microenvironmental Modulation of Extracellular Vesicle-Dependent Immunoregulation in the Lung.
Daniel J Schneider, Jennifer M Speth, Marc Peters-Golden

Front Cell Dev Biol· September 2016

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Alveolar Epithelial Cell-Derived Prostaglandin E2 Serves as a Request Signal for Macrophage Secretion of Suppressor of Cytokine Signaling 3 during Innate Inflammation.
Jennifer M Speth, Emilie Bourdonnay, Loka Raghu Kumar Penke, Peter Mancuso, Bethany B Moore

J Immunol· June 2016

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Transcellular delivery of vesicular SOCS proteins from macrophages to epithelial cells blunts inflammatory signaling.
Emilie Bourdonnay, Zbigniew Zasłona, Loka Raghu Kumar Penke, Jennifer M Speth, Daniel J Schneider

J Exp Med· May 2015

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Pharmacologic increase in HIF1α enhances hematopoietic stem and progenitor homing and engraftment.
Jennifer M Speth, Jonathan Hoggatt, Pratibha Singh, Louis M Pelus

Blood· January 2014

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Concise review: Sowing the seeds of a fruitful harvest: hematopoietic stem cell mobilization.
Jonathan Hoggatt, Jennifer M Speth, Louis M Pelus

Stem Cells· December 2013

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Differential stem- and progenitor-cell trafficking by prostaglandin E2.
Jonathan Hoggatt, Khalid S Mohammad, Pratibha Singh, Amber F Hoggatt, Brahmananda R Chitteti, Jennifer M Speth

Nature· March 2013

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Blockade of prostaglandin E2 signaling through EP1 and EP3 receptors attenuates Flt3L-dependent dendritic cell development from hematopoietic progenitor cells.
Pratibha Singh, Jonathan Hoggatt, Peirong Hu, Jennifer M Speth, Seiji Fukuda

Blood· February 2012

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