Publications by authors named "Jennifer Mehrens"

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A Novel T-Cell Engaging Bi-specific Antibody Targeting the Leukemia Antigen PR1/HLA-A2.
Amanda C Herrmann, Jin S Im, Sumedha Pareek, Wilfredo Ruiz-Vasquez, Sijie Lu, Jennifer Mehrens

Front Immunol· October 2019

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Neuropilin-1 mediates neutrophil elastase uptake and cross-presentation in breast cancer cells.
Celine Kerros, Satyendra C Tripathi, Dongxing Zha, Jennifer M Mehrens, Anna Sergeeva

J Biol Chem· June 2017

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Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.
Ying Wu, Leonardus M I Koharudin, Jennifer Mehrens, Maria DeLucia, Chang-Hyeok Byeon

J Biol Chem· July 2015

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Structural basis of allosteric activation of sterile α motif and histidine-aspartate domain-containing protein 1 (SAMHD1) by nucleoside triphosphates.
Leonardus M I Koharudin, Ying Wu, Maria DeLucia, Jennifer Mehrens, Angela M Gronenborn

J Biol Chem· November 2014

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Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1.
Oliver I Fregoso, Jinwoo Ahn, Chuanping Wang, Jennifer Mehrens, Jacek Skowronski

PLoS Pathog· February 2014

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Mechanisms of allosteric activation and inhibition of the deoxyribonucleoside triphosphate triphosphohydrolase from Enterococcus faecalis.
Ivan I Vorontsov, Ying Wu, Maria DeLucia, George Minasov, Jennifer Mehrens

J Biol Chem· January 2014

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Mechanism of allosteric activation of SAMHD1 by dGTP.
Xiaoyun Ji, Ying Wu, Junpeng Yan, Jennifer Mehrens, Haitao Yang

Nat Struct Mol Biol· November 2013

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HIV-2 and SIVmac accessory virulence factor Vpx down-regulates SAMHD1 enzyme catalysis prior to proteasome-dependent degradation.
Maria DeLucia, Jennifer Mehrens, Ying Wu, Jinwoo Ahn

J Biol Chem· June 2013

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Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection.
Junpeng Yan, Sarabpreet Kaur, Maria DeLucia, Caili Hao, Jennifer Mehrens

J Biol Chem· April 2013

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HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1.
Jinwoo Ahn, Caili Hao, Junpeng Yan, Maria DeLucia, Jennifer Mehrens

J Biol Chem· April 2012

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