Publications by authors named "Jennifer Watanabe"

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A chikungunya virus-like particle vaccine reduces chikungunya disease in cynomolgus macaques and protection is mediated by antibody transferred from vaccinated humans.
Lark L Coffey, Katherine J Olstad, J Rachel Reader, Amir Ardeshir, Christopher M Weiss, Jennifer K Watanabe

Res Sq· November 2025

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Rhesus macaques model human Mayaro virus disease and transmit to Aedes aegypti mosquitoes.
Adam J Moore, Koen K A Van Rompay, William Louie, Jennifer K Watanabe, Sunny An

PLoS Negl Trop Dis· October 2025

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Targeting of phosphorylated tau at threonine 181 by a Qβ virus-like particle vaccine is safe, highly immunogenic, and reduces disease severity in mice and rhesus macaques.
Nicole M Maphis, Jonathan Hulse, Julianne Peabody, Somayeh Dadras, Madelin J Whelpley, Jennifer W Watanabe

Alzheimers Dement· March 2025

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FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques.
Joanna Zikos, Gabriela M Webb, Helen L Wu, Jason S Reed, Jennifer Watanabe

MAbs· September 2024

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A virus-like particle-based bivalent PCSK9 vaccine lowers LDL-cholesterol levels in non-human primates.
Alexandra Fowler, Koen K A Van Rompay, Maureen Sampson, Javier Leo, Jennifer K Watanabe

NPJ Vaccines· September 2023

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A Virus-like particle-based bivalent PCSK9 vaccine lowers LDL-cholesterol levels in Non-Human Primates.
Alexandra Fowler, Koen K A Van Rompay, Maureen Sampson, Javier Leo, Jennifer K Watanabe

bioRxiv· May 2023

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Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge 1 year later.
Emma C Milligan, Katherine Olstad, Caitlin A Williams, Michael Mallory, Patricio Cano, Jennifer Watanabe

Sci Transl Med· March 2023

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Dam-Infant Rhesus Macaque Pairs to Dissect Age-Dependent Responses to SARS-CoV-2 Infection.
Stephanie N Langel, Carolina Garrido, Caroline Phan, Tatianna Travieso, Helene Kirshner, Jennifer Watanabe

Immunohorizons· December 2022

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Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity had no antiviral effects but moderately reduced lung inflammation.
Koen K A Van Rompay, Katherine J Olstad, Rebecca L Sammak, Joseph Dutra, Jennifer K Watanabe

PLoS Pathog· April 2022

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SARS-CoV-2 Infection of Rhesus Macaques Treated Early with Human COVID-19 Convalescent Plasma.
Jesse D Deere, Timothy D Carroll, Joseph Dutra, Linda Fritts, Rebecca Lee Sammak, Jennifer Watanabe

Microbiol Spectr· December 2021

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Monoclonal antibodies protect aged rhesus macaques from SARS-CoV-2-induced immune activation and neuroinflammation.
Anil Verma, Chase E Hawes, Yashavanth Shaan Lakshmanappa, Jamin W Roh, Brian A Schmidt, Jennifer K Watanabe

Cell Rep· November 2021

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Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammation.
Koen K A Van Rompay, Katherine J Olstad, Rebecca L Sammak, Joseph Dutra, Jennifer K Watanabe

bioRxiv· September 2021

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Early treatment with a combination of two potent neutralizing antibodies improves clinical outcomes and reduces virus replication and lung inflammation in SARS-CoV-2 infected macaques.
Koen K A Van Rompay, Katherine J Olstad, Rebecca L Sammak, Joseph Dutra, Jennifer K Watanabe

PLoS Pathog· July 2021

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SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques.
Yashavanth Shaan Lakshmanappa, Sonny R Elizaldi, Jamin W Roh, Brian A Schmidt, Timothy D Carroll, Jennifer Watanabe

Nat Commun· January 2021

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Evolution of ocular defects in infant macaques following in utero Zika virus infection.
Glenn Yiu, Sara M Thomasy, M Isabel Casanova, Alexander Rusakevich, Rebekah I Keesler, Jennifer Watanabe

JCI Insight· December 2020

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Two Sides of a Coin: a Zika Virus Mutation Selected in Pregnant Rhesus Macaques Promotes Fetal Infection in Mice but at a Cost of Reduced Fitness in Nonpregnant Macaques and Diminished Transmissibility by Vectors.
Danilo Lemos, Jackson B Stuart, William Louie, Anil Singapuri, Ana L Ramírez, Jennifer Watanabe

J Virol· November 2020

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SARS-CoV-2 infection induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques.
Sonny Elizaldi, Yashavanth Shaan Lakshmanappa, Jamin Roh, Brian Schmidt, Timothy Carroll, Jennifer Watanabe

Res Sq· August 2020

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SARS-CoV-2 infection induces germinal center responses with robust stimulation of CD4 T follicular helper cells in rhesus macaques.
Sonny R Elizaldi, Yashavanth Shaan Lakshmanappa, Jamin W Roh, Brian A Schmidt, Timothy D Carroll, Jennifer Watanabe

bioRxiv· July 2020

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A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques.
Koen K A Van Rompay, Lark L Coffey, Tania Kapoor, Anna Gazumyan, Rebekah I Keesler, Jennifer Watanabe

Proc Natl Acad Sci U S A· April 2020

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DNA vaccination before conception protects Zika virus-exposed pregnant macaques against prolonged viremia and improves fetal outcomes.
Koen K A Van Rompay, Rebekah I Keesler, Amir Ardeshir, Jennifer Watanabe, Jodie Usachenko

Sci Transl Med· December 2019

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Dolutegravir Monotherapy of Simian Immunodeficiency Virus-Infected Macaques Selects for Several Patterns of Resistance Mutations with Variable Virological Outcomes.
Koen K A Van Rompay, Said Hassounah, Brandon F Keele, Jeffrey D Lifson, Amir Ardeshir, Jennifer Watanabe

J Virol· January 2019

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A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.
Jennifer R Keeffe, Koen K A Van Rompay, Priscilla C Olsen, Qiao Wang, Anna Gazumyan, Jennifer Watanabe

Cell Rep· November 2018

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Intraamniotic Zika virus inoculation of pregnant rhesus macaques produces fetal neurologic disease.
Lark L Coffey, Rebekah I Keesler, Patricia A Pesavento, Kevin Woolard, Anil Singapuri, Jennifer Watanabe

Nat Commun· June 2018

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Zika Virus Tissue and Blood Compartmentalization in Acute Infection of Rhesus Macaques.
Lark L Coffey, Patricia A Pesavento, Rebekah I Keesler, Anil Singapuri, Jennifer Watanabe, Rie Watanabe

PLoS One· August 2017

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