Publications by authors named "Jens D Mikkelsen"

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Positive correlation between cognition and inflammation in the cerebral cortex of patients with mesial temporal lobe epilepsy.
Aje Al-Awssi, Burcu A Pazarlar, Lars H Pinborg, Jens D Mikkelsen

Epilepsy Behav· December 2025

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Astroglial TNFR2 signaling regulates hippocampal synaptic function and plasticity in a sex dependent manner.
Brianna N Carney, Placido Illiano, Taylor M Pohl, Haritha L Desu, Antonella Mini, Jens D Mikkelsen

Brain Behav Immun· October 2025

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[H]T-401 binding to monoacylglycerol lipase (MAGL) in the brains of patients and mice with temporal lobe epilepsy.
Sanjay S Aripaka, Burcu A Pazarlar, Lars H Pinborg, Karen B Larsen, Francois Gastambide, Jens D Mikkelsen

Neuroscience· October 2025

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TNFR2 signaling shapes the sex-specific remyelinating properties of microglia after experimental stroke.
Stefano Raffaele, Francesca Carolina Mannella, Estrid Thougaard, Pernille Vinther Nielsen, Morten Blickfeldt-Eckhardt, Jens D Mikkelsen

Neurotherapeutics· October 2025

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Increased Expression of Synaptic Vesicle Glycoprotein 2A (SV2A) in the Brain of Chronic Diabetic Rats.
Burcu Azak Pazarlar, Cansu Bilister Egilmez, Eser Öz Oyar, Jens D Mikkelsen

Synapse· May 2025

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Astroglial TNFR2 signaling regulates hippocampal synaptic function and plasticity in a sex dependent manner.
Brianna N Carney, Placido Illiano, Taylor M Pohl, Haritha L Desu, Shwetha Mudalegundi, Jens D Mikkelsen

bioRxiv· March 2025

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Higher level of [H]UCB-J binding in ApoE Ɛ4 allele carriers with Alzheimer disease.
Jens D Mikkelsen, Phoebe Linde-Atkins, Burcu A Pazarlar

Neurosci Lett· February 2025

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Expression of cytokines at baseline correlate/predict in the disc the outcome of surgery after disc degeneration: A 12-month follow-up study.
Sanjay S Aripaka, Sajjad Ahmad Chughtai, Louise M Jørgensen, Rachid Bech-Azeddine, Jens D Mikkelsen

Pain Pract· November 2024

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The effect of antidepressant treatment on blood BDNF levels in depressed patients: A review and methodological recommendations for assessment of BDNF in blood.
Clara A Madsen, Miriam L Navarro, Betina Elfving, Lars V Kessing, Eero Castrén, Jens D Mikkelsen

Eur Neuropsychopharmacol· October 2024

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Binding of the monoacylglycerol lipase (MAGL) radiotracer [H]T-401 in the rat brain after status epilepticus.
Jens D Mikkelsen, Sanjay S Aripaka, Cansu B Egilmez, Burcu A Pazarlar

Neurochem Int· May 2024

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Characterizing the binding of TC-5619 and encenicline on the alpha7 nicotinic acetylcholine receptor using PET imaging in the pig.
Janus H Magnussen, Anders Ettrup, Szabolcs Lehel, Dan Peters, Agnete Dyssegaard, Jens D Mikkelsen

Front Neuroimaging· March 2024

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Systemic treatment with a selective TNFR2 agonist alters the central and peripheral immune responses and transiently improves functional outcome after experimental ischemic stroke.
Estrid Thougaard, Pernille Vinther Nielsen, Amalie Forsberg, Victoria Phuong, Aitana Martínez Velasco, Jens D Mikkelsen

J Neuroimmunol· December 2023

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Synaptic vesicle glycoprotein 2A (SV2A) levels in the cerebral cortex in patients with Alzheimer's disease: a radioligand binding study in postmortem brains.
Jens D Mikkelsen, Sif Kaad, Sanjay S Aripaka, Bente Finsen

Neurobiol Aging· September 2023

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Subacute effects of a single dose of psilocybin on biomarkers of inflammation in healthy humans: An open-label preliminary investigation.
Daniel Rødbro Burmester, Martin Korsbak Madsen, Attila Szabo, Sagar Sanjay Aripaka, Dea Siggaard Stenbæk, Jens D Mikkelsen

Compr Psychoneuroendocrinol· February 2023

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Transient receptor potential (TRP) channels mRNA transcripts in the lumbar intervertebral discs: biomarkers for inflammation, pain, disability, and clinical outcome.
Sanjay S Aripaka, Rachid Bech-Azeddine, Louise M Jørgensen, Jens D Mikkelsen

Mol Cell Biochem· January 2023

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Characterization of the Novel P2X7 Receptor Radioligand [H]JNJ-64413739 in Human Brain Tissue.
Jens D Mikkelsen, Sanjay S Aripaka, Sif Kaad, Burcu A Pazarlar, Lars Pinborg

ACS Chem Neurosci· January 2023

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Synergistic effect of serotonin 1A and serotonin 1B/D receptor agonists in the treatment of L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rats.
Mikael Thomsen, Anca Stoica, Kenneth Vielsted Christensen, Tue Fryland, Jens D Mikkelsen

Exp Neurol· December 2022

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Spatio-Temporal Alterations in Synaptic Density During Epileptogenesis in the Rat Brain.
Jens D Mikkelsen, Sanjay S Aripaka, Pablo Bascuñana, Marion Bankstahl, Jens P Bankstahl

Neuroscience· September 2022

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Temporal and spatial changes in synaptic vesicle glycoprotein 2A (SV2A) under kainic acid induced epileptogenesis: An autoradiographic study.
Burcu Azak Pazarlar, Clara A Madsen, Eser Öz Oyar, Cansu B Eğilmez, Jens D Mikkelsen

Epilepsy Res· July 2022

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Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE).
Burcu A Pazarlar, Sanjay S Aripaka, Viktor Petukhov, Lars Pinborg, Konstantin Khodosevich, Jens D Mikkelsen

Mol Brain· May 2022

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The expression of metalloproteinases in the lumbar disc correlates strongly with Pfirrmann MRI grades in lumbar spinal fusion patients.
Sanjay S Aripaka, Rachid Bech-Azeddine, Louise M Jørgensen, Jens D Mikkelsen

Brain Spine· February 2022

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Synaptic Density and Neuronal Metabolic Function Measured by Positron Emission Tomography in the Unilateral 6-OHDA Rat Model of Parkinson's Disease.
Nakul Ravi Raval, Frederik Gudmundsen, Morten Juhl, Ida Vang Andersen, Nikolaj Speth, Jens D Mikkelsen

Front Synaptic Neurosci· November 2021

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Anti-Inflammatory Effect of Alpha7 Nicotinic Acetylcholine Receptor Modulators on BV2 Cells.
Sanjay S Aripaka, Jens D Mikkelsen

Neuroimmunomodulation· October 2021

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NH- and N-Substituted Phenylguanidines as α7 Nicotinic Acetylcholine (nACh) Receptor Antagonists: Structure-Activity Relationship Studies.
Osama I Alwassil, Shailesh Khatri, Marvin K Schulte, Sanjay S Aripaka, Jens D Mikkelsen

ACS Chem Neurosci· June 2021

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In Vitro and In Vivo Characterization of Dibenzothiophene Derivatives [I]Iodo-ASEM and [F]ASEM as Radiotracers of Homo- and Heteromeric α7 Nicotinic Acetylcholine Receptors.
Cornelius K Donat, Henrik H Hansen, Hanne D Hansen, Ronnie C Mease, Andrew G Horti, Jens D Mikkelsen

Molecules· March 2020

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