Publications by authors named "Jeremy A Simpson"

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The mitochondrial-targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial-apoptotic but not necroptotic signalling during ovarian cancer.
Shahrzad Khajehzadehshoushtar, Luca J Delfinis, Fasih A Rahman, Madison C Garibotti, Shivam Gandhi, Jeremy A Simpson

J Physiol· November 2025

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Adiponectin-receptor agonism prevents right ventricular tissue pathology in a mouse model of Duchenne muscular dystrophy.
Shivam Gandhi, Luca J Delfinis, Parashar D Bhatt, Madison C Garibotti, Catherine A Bellissimo, Jeremy A Simpson

Mol Metab· September 2025

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Mitochondrial-targeted plastoquinone therapy prevents early onset muscle weakness that occurs before atrophy during ovarian cancer.
Luca J Delfinis, Shahrzad Khajehzadehshoushtar, Luke D Flewwelling, Nathaniel J Andrews, Madison C Garibotti, Jeremy A Simpson

Mol Metab· September 2025

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Guidelines for assessing ventricular pressure-volume relationships in rodents.
Oliver H Wearing, Naomi C Chesler, Mitchel J Colebank, Timothy A Hacker, John N Lorenz, Jeremy A Simpson

Am J Physiol Heart Circ Physiol· January 2025

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Cardiac Atrophy, Dysfunction, and Metabolic Impairments: A Cancer-Induced Cardiomyopathy Phenotype.
Leslie M Ogilvie, Luca J Delfinis, Bridget Coyle-Asbil, Vignesh Vudatha, Razan Alshamali, Jeremy A Simpson

Am J Pathol· October 2024

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Mitohormesis during advanced stages of Duchenne muscular dystrophy reveals a redox-sensitive creatine pathway that can be enhanced by the mitochondrial-targeting peptide SBT-20.
Meghan C Hughes, Sofhia V Ramos, Aditya N Brahmbhatt, Patrick C Turnbull, Nazari N Polidovitch, Jeremy A Simpson

Redox Biol· October 2024

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Yap Is a Nutrient Sensor Sensitive to the Amino Acid L-Isoleucine and Regulates the Expression of Ctgf in Cardiomyocytes.
Victoria L Nelson, Ashley L Eadie, Lester Perez, Malav Madhu, Mathew Platt, Jeremy A Simpson

Biomolecules· October 2024

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Mitochondrial-targeted plastoquinone therapy ameliorates early onset muscle weakness that precedes ovarian cancer cachexia in mice.
Luca J Delfinis, Shahrzad Khajehzadehshoushtar, Luke D Flewwelling, Nathaniel J Andrews, Madison C Garibotti, Jeremy A Simpson

bioRxiv· October 2024

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Cardiac fibroblasts: answering the call.
Petra Kleinbongard, Samuel E Senyo, Merry L Lindsey, Alexandra M Garvin, Jeremy A Simpson

Am J Physiol Heart Circ Physiol· September 2024

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Teaching an old drug new tricks: Regulatory insights for the repurposing of hemin in cardiovascular disease.
Ashley L Eadie, Jeremy A Simpson, Keith R Brunt

Pharmacol Res Perspect· August 2024

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Muscle weakness and mitochondrial stress occur before severe metastasis in a novel mouse model of ovarian cancer cachexia.
Luca J Delfinis, Leslie M Ogilvie, Shahrzad Khajehzadehshoushtar, Shivam Gandhi, Madison C Garibotti, Jeremy A Simpson

Mol Metab· August 2024

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Cardiomyocyte crosstalk with endothelium modulates cardiac structure, function, and ischemia-reperfusion injury susceptibility through erythropoietin.
Jade P Marrow, Razan Alshamali, Brittany A Edgett, Melissa A Allwood, Kyla L S Cochrane, Jeremy A Simpson

Front Physiol· July 2024

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Therapy-naïve malignancy causes cardiovascular disease: a state-of-the-art cardio-oncology perspective.
Leslie M Ogilvie, Bridget Coyle-Asbil, Keith R Brunt, Jim Petrik, Jeremy A Simpson

Am J Physiol Heart Circ Physiol· June 2024

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Bilateral nephrectomy impairs cardiovascular function and cerebral perfusion in a rat model of acute hemodilutional anemia.
Kyle Chin, Helen Jiang, Benjamin E Steinberg, Neil M Goldenberg, Jean-Francois Desjardins, Jeremy A Simpson

J Appl Physiol (1985)· May 2024

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Better Respiratory Function in Heart Failure Patients With Use of Central-Acting Therapeutics.
Julie K K Vishram-Nielsen, Fernando Luis Scolari, Chun-Po Steve Fan, Yas Moayedi, Heather J Ross, Jeremy A Simpson

CJC Open· May 2024

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Muscle weakness and mitochondrial stress occur before metastasis in a novel mouse model of ovarian cancer cachexia.
Luca J Delfinis, Leslie M Ogilvie, Shahrzad Khajehzadehshoushtar, Shivam Gandhi, Madison C Garibotti, Jeremy A Simpson

bioRxiv· April 2024

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Intron retention is a mechanism of erythropoietin regulation in brain cell models.
Victoria Northrup, Lester J Perez, Brittany A Edgett, Tobias Karakach, Jeremy A Simpson

Gene· March 2024

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Novel roles of cardiac-derived erythropoietin in cardiac development and function.
Melissa A Allwood, Brittany A Edgett, Mathew J Platt, Jade P Marrow, Bridget Coyle-Asbil, Jeremy A Simpson

J Mol Cell Cardiol· March 2024

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Dietary Nitrate and Corresponding Gut Microbiota Prevent Cardiac Dysfunction in Obese Mice.
Heather L Petrick, Leslie M Ogilvie, Henver S Brunetta, Avery Robinson, Aleah J Kirsh, Jeremy A Simpson

Diabetes· July 2023

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Emerging roles for estrogen in regulating skeletal muscle physiology.
Bridget Coyle-Asbil, Leslie M Ogilvie, Jeremy A Simpson

Physiol Genomics· February 2023

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Cigarette smoke augments CSF3 expression in neutrophils to compromise alveolar-capillary barrier function during influenza infection.
Joshua J C McGrath, Gilles Vanderstocken, Anna Dvorkin-Gheva, Steven P Cass, Sam Afkhami, Jeremy A Simpson

Eur Respir J· August 2022

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Complementary Nck1/2 Signaling in Podocytes Controls Actinin-4-Mediated Actin Organization, Adhesion, and Basement Membrane Composition.
Claire E Martin, Noah J Phippen, Ava Keyvani Chahi, Manali Tilak, Sara L Banerjee, Jeremy A Simpson

J Am Soc Nephrol· August 2022

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An Evaluation of Cardiac Health in the Spontaneously Hypertensive Rat Colony: Implications of Evolutionary Driven Increases in Concentric Hypertrophy.
Emma J B Holjak, Iryna Savinova, Victoria L Nelson, Leslie M Ogilvie, Anabelle M Ng, Jeremy A Simpson

Am J Hypertens· March 2022

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Regional cardiac strain mapping by four-dimensional ultrasound provides earlier detection of systolic and diastolic dysfunction.
Leslie M Ogilvie, Bridget Coyle-Asbil, Keith R Brunt, Jeremy A Simpson

Am J Physiol Heart Circ Physiol· August 2021

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A new approach to improve the hemodynamic assessment of cardiac function independent of respiratory influence.
Leslie M Ogilvie, Brittany A Edgett, Simon Gray, Sally Al-Mufty, Jason S Huber, Jeremy A Simpson

Sci Rep· August 2021

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