Publications by authors named "Jeremy D Rotty"

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Key features of the innate immune response is mediated by the immunoproteasome in microglia.
Salman Izadjoo, Kasey E Moritz, Guzal Khayrullina, Elizabeth M Bergman, Brendan M Melvin, Jeremy D Rotty

Sci Rep· November 2025

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Physical confinement and phagocytic uptake induce persistent cell migration.
Summer G Paulson, Sophia Liu, Jeremy D Rotty

Biol Open· September 2025

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Macrophages migrate persistently and directionally upon entering 2D confinement in the presence of extracellular matrix.
Matthew W Stinson, Summer G Paulson, Ethan M Carlile, Jeremy D Rotty

Biol Open· July 2025

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Phactr4 influences macrophage lamellipodial structure and dynamics through Arp2/3 complex and Ezrin regulation.
Rohini Manickam, Jeremy D Rotty

bioRxiv· May 2025

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Macrophages migrate persistently and directionally upon entering 2D confinement in the presence of extracellular matrix.
Matthew W Stinson, Summer G Paulson, Ethan M Carlile, Jeremy D Rotty

bioRxiv· May 2025

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Physical confinement and phagocytic uptake induce directional migration.
Summer G Paulson, Sophia Liu, Jeremy D Rotty

bioRxiv· May 2025

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The Arp2/3 complex is required for haptotactic response of microglia to iC3b.
Summer G Paulson, Isabella Swafford, Fritz W Lischka, Jeremy D Rotty

bioRxiv· May 2025

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Key features of the innate immune response is mediated by the immunoproteasome in microglia.
Salman Izadjoo, Kasey E Moritz, Guzal Khayrullina, Elizabeth M Bergman, Brendan M Melvin, Jeremy D Rotty

Res Sq· June 2024

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Local monomer levels and established filaments potentiate non-muscle myosin 2 assembly.
Melissa A Quintanilla, Hiral Patel, Huini Wu, Kem A Sochacki, Shreya Chandrasekar, Jeremy D Rotty

J Cell Biol· April 2024

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Macrophage migration is differentially regulated by fibronectin and laminin through altered adhesion and myosin II localization.
Matthew W Stinson, Sophia Liu, Alexander J Laurenson, Jeremy D Rotty

Mol Biol Cell· February 2024

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Local Monomer Levels and Established Filaments Potentiate Non-Muscle Myosin 2 Assembly.
Melissa A Quintanilla, Hiral Patel, Huini Wu, Kem A Sochacki, Matthew Akamatsu, Jeremy D Rotty

bioRxiv· April 2023

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Macrophage migration is differentially regulated by distinct ECM components.
Matthew W Stinson, Alexander J Laurenson, Jeremy D Rotty

bioRxiv· April 2023

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The Actin Cytoskeleton Responds to Inflammatory Cues and Alters Macrophage Activation.
Elsa Ronzier, Alexander J Laurenson, Rohini Manickam, Sophia Liu, Imelda M Saintilma, Jeremy D Rotty

Cells· May 2022

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Dynein activation in vivo is regulated by the nucleotide states of its AAA3 domain.
Rongde Qiu, Jun Zhang, Jeremy D Rotty, Xin Xiang

Curr Biol· October 2021

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Actin Cytoskeleton: Profilin Gives Cells an Edge.
Jeremy D Rotty

Curr Biol· July 2020

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Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation.
Steven Tessier, Alexandra C Doolittle, Kimheak Sao, Jeremy D Rotty, James E Bear

JCI Insight· February 2020

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Myeloid -Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1.
Alex J Freemerman, Liyang Zhao, Ajeeth K Pingili, Bin Teng, Alyssa J Cozzo, Jeremy D Rotty

J Immunol· February 2019

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Lack of myeloid Fatp1 increases atherosclerotic lesion size in Ldlr mice.
Liyang Zhao, Alyssa J Cozzo, Amy R Johnson, Taylor Christensen, Alex J Freemerman, Jeremy D Rotty

Atherosclerosis· November 2017

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Arp2/3 Complex Is Required for Macrophage Integrin Functions but Is Dispensable for FcR Phagocytosis and In Vivo Motility.
Jeremy D Rotty, Hailey E Brighton, Stephanie L Craig, Sreeja B Asokan, Ning Cheng

Dev Cell· September 2017

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Deletion of the Arp2/3 complex in megakaryocytes leads to microthrombocytopenia in mice.
David S Paul, Caterina Casari, Congying Wu, Raymond Piatt, Swetha Pasala, Jeremy D Rotty

Blood Adv· August 2017

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Lamellipodia are crucial for haptotactic sensing and response.
Samantha J King, Sreeja B Asokan, Elizabeth M Haynes, Seth P Zimmerman, Jeremy D Rotty

J Cell Sci· June 2016

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Competition and collaboration between different actin assembly pathways allows for homeostatic control of the actin cytoskeleton.
Jeremy D Rotty, James E Bear

Bioarchitecture· April 2016

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F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling.
Heath E Johnson, Samantha J King, Sreeja B Asokan, Jeremy D Rotty, James E Bear

J Cell Biol· February 2015

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Profilin-1 serves as a gatekeeper for actin assembly by Arp2/3-dependent and -independent pathways.
Jeremy D Rotty, Congying Wu, Elizabeth M Haynes, Cristian Suarez, Jonathan D Winkelman

Dev Cell· January 2015

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Mesenchymal chemotaxis requires selective inactivation of myosin II at the leading edge via a noncanonical PLCγ/PKCα pathway.
Sreeja B Asokan, Heath E Johnson, Anisur Rahman, Samantha J King, Jeremy D Rotty

Dev Cell· December 2014

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