Publications by authors named "Jeremy Heidel"

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A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma.
Priya Kumthekar, Caroline H Ko, Tatjana Paunesku, Karan Dixit, Adam M Sonabend, Jeremy Heidel

Sci Transl Med· March 2021

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Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA.
Jonathan E Zuckerman, Ismael Gritli, Anthony Tolcher, Jeremy D Heidel, Dean Lim

Proc Natl Acad Sci U S A· August 2014

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Cyclodextrin-containing polymers: versatile platforms of drug delivery materials.
Jeremy D Heidel, Thomas Schluep

J Drug Deliv· August 2012

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Cyclodextrin-containing polycations for nucleic acid delivery.
Jeremy D Heidel

Cold Spring Harb Protoc· November 2011

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In vitro transfection using cyclodextrin-containing polycations.
Jeremy D Heidel

Cold Spring Harb Protoc· November 2011

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In vivo transfection using cyclodextrin-containing polycations.
Jeremy D Heidel

Cold Spring Harb Protoc· November 2011

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Clinical developments in nanotechnology for cancer therapy.
Jeremy D Heidel, Mark E Davis

Pharm Res· February 2011

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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles.
Mark E Davis, Jonathan E Zuckerman, Chung Hang J Choi, David Seligson, Anthony Tolcher, Jeremy D Heidel

Nature· April 2010

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Development of universal antidotes to control aptamer activity.
Sabah Oney, Ruby T S Lam, Kristin M Bompiani, Charlene M Blake, George Quick, Jeremy D Heidel

Nat Med· October 2009

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Targeted delivery of siRNA to cell death proteins in sepsis.
Pavan Brahmamdam, Eizo Watanabe, Jacqueline Unsinger, Katherine C Chang, William Schierding, Jeremy D Heidel

Shock· August 2009

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Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA.
Jeremy D Heidel, Zhongping Yu, Joanna Yi-Ching Liu, Shyam M Rele, Yongchao Liang

Proc Natl Acad Sci U S A· April 2007

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Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo.
Jeremy D Heidel, Joanna Yi-Ching Liu, Yun Yen, Bingsen Zhou, Bret S E Heale

Clin Cancer Res· April 2007

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Imidazole groups on a linear, cyclodextrin-containing polycation produce enhanced gene delivery via multiple processes.
Swaroop Mishra, Jeremy D Heidel, Paul Webster, Mark E Davis

J Control Release· November 2006

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Linear cyclodextrin-containing polymers and their use as delivery agents.
Jeremy D Heidel

Expert Opin Drug Deliv· September 2006

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Molecular conjugates.
Jeremy Heidel, Swaroop Mishra, Mark E Davis

Adv Biochem Eng Biotechnol· June 2006

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Preclinical efficacy of the camptothecin-polymer conjugate IT-101 in multiple cancer models.
Thomas Schluep, Jungyeong Hwang, Jianjun Cheng, Jeremy D Heidel, Derek W Bartlett

Clin Cancer Res· March 2006

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Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma.
Siwen Hu-Lieskovan, Jeremy D Heidel, Derek W Bartlett, Mark E Davis, Timothy J Triche

Cancer Res· October 2005

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Functional polarity is introduced by Dicer processing of short substrate RNAs.
Scott D Rose, Dong-Ho Kim, Mohammed Amarzguioui, Jeremy D Heidel, Michael A Collingwood

Nucleic Acids Res· August 2005

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Cyclodextrin-modified polyethylenimine polymers for gene delivery.
Suzie H Pun, Nathalie C Bellocq, Aijie Liu, Greg Jensen, Todd Machemer, Jeremy Heidel

Bioconjug Chem· January 2005

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Lack of interferon response in animals to naked siRNAs.
Jeremy D Heidel, Siwen Hu, Xian Fang Liu, Timothy J Triche, Mark E Davis

Nat Biotechnol· December 2004

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