Publications by authors named "Jerome Dayer"

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Revealing Unpredicted Aspartic Acid Isomerization Hotspots by Probing Diagnostic Fragmentation Propensities in Top-Down and Middle-Down Mass Spectrometry.
Blandine Denefeld, Joanna Hajduk, Jure Cerar, Jean-Michel Rondeau, Jérôme Dayer

J Am Soc Mass Spectrom· May 2025

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Restoring the biological activity of crizanlizumab at physiological conditions through a pH-dependent aspartic acid isomerization reaction.
Fabian Bickel, François Griaud, Wolfram Kern, Frieder Kroener, Manuela Gritsch, Jérôme Dayer

MAbs· December 2022

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Preclinical pharmacokinetics and metabolism of MAK683, a clinical stage selective oral embryonic ectoderm development (EED) inhibitor for cancer treatment.
Ji Yue Jeff Zhang, Jiangwei Zhang, Michael Kiffe, Markus Walles, Yi Jin, Jerôme Dayer

Xenobiotica· January 2022

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All Ion Differential Analysis Refines the Detection of Terminal and Internal Diagnostic Fragment Ions for the Characterization of Biologics Product-Related Variants and Impurities by Middle-down Mass Spectrometry.
François Griaud, Blandine Denefeld, Chi-Ya Kao-Scharf, Jérôme Dayer, Manuel Lang

Anal Chem· July 2019

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Evaluation of relative MS response factors of drug metabolites for semi-quantitative assessment of chemical liabilities in drug discovery.
Joachim Blanz, Gareth Williams, Jerôme Dayer, Thierry Délémonté, Werner Gertsch

J Mass Spectrom· April 2017

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Micropreparative isolation and NMR structure elucidation of metabolites of the drug candidate 1-isopropyl-4-(4-isopropylphenyl)-6-(prop-2-yn-1-yloxy) quinazolin-2(1H)-one from rat bile and urine.
Joachim Blanz, Thierry Délémonté, David Pearson, Alexandre Luneau, Michael Ritzau, Jérôme Dayer

J Chromatogr B Analyt Technol Biomed Life Sci· May 2015

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