Publications by authors named "Jesper Heldrup"

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Retraction Note: New recommendations for reversal of high-dose methotrexate cytotoxicity with folinic acid.
Jesper Heldrup, Archie Bleyer, Laura Ramsey, Lauren Schaff, Brooke Bernhardt

Cancer Chemother Pharmacol· July 2025

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Methotrexate and glucarpidase: the emperor has new clothes.
Stefan Schwartz, Jesper Heldrup

Blood· April 2025

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New recommendations for reversal of high-dose methotrexate cytotoxicity with folinic acid.
Jesper Heldrup, Archie Bleyer, Laura Ramsey, Lauren Schaff, Brooke Bernhardt

Cancer Chemother Pharmacol· March 2025

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Hypoalbuminemia in children with acute lymphoblastic leukemia: relation to asparaginase therapy and impact on high dose methotrexate elimination.
Sophie Rex Christensen, Christina Friis Jensen, Jesper Heldrup, Zachary Taylor, Laura B Ramsey

Cancer Chemother Pharmacol· December 2024

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Insights from a pharmacometric analysis of HDMTX in adults with cancer: Clinically relevant covariates for application in precision dosing.
Manuel Ibarra, Ryan Combs, Zachary L Taylor, Laura B Ramsey, Torben Mikkelsen, Jesper Heldrup

Br J Clin Pharmacol· February 2023

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Extracorporeal Treatment for Methotrexate Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup.
Marc Ghannoum, Darren M Roberts, David S Goldfarb, Jesper Heldrup, Kurt Anseeuw

Clin J Am Soc Nephrol· April 2022

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Simultaneous determination of folate and methotrexate metabolites in serum by LC-MS/MS during high-dose methotrexate therapy.
Karin Hansson, Henrik Orrling, Anders Blomgren, Anders Isaksson, Gloria Schliamser, Jesper Heldrup

J Chromatogr B Analyt Technol Biomed Life Sci· December 2021

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MTXPK.org: A Clinical Decision Support Tool Evaluating High-Dose Methotrexate Pharmacokinetics to Inform Post-Infusion Care and Use of Glucarpidase.
Zachary L Taylor, Tomoyuki Mizuno, Nieko C Punt, Balaji Baskaran, Adriana Navarro Sainz, Jesper Heldrup

Clin Pharmacol Ther· September 2020

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Plasma creatinine as predictor of delayed elimination of high-dose methotrexate in childhood acute lymphoblastic leukemia: A Danish population-based study.
Diana Schmidt, Kim Kristensen, Henrik Schroeder, Peder Skov Wehner, Steen Rosthøj, Jesper Heldrup

Pediatr Blood Cancer· June 2019

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Consensus Guideline for Use of Glucarpidase in Patients with High-Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance.
Laura B Ramsey, Frank M Balis, Maureen M O'Brien, Kjeld Schmiegelow, Jennifer L Pauley, Jesper Heldrup

Oncologist· January 2018

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Delayed elimination of high-dose methotrexate and use of carboxypeptidase G2 in pediatric patients during treatment for acute lymphoblastic leukemia.
Thommy Svahn, Karin Mellgren, Arja Harila-Saari, Ann Åsberg, Jukka Kanerva, Jesper Heldrup

Pediatr Blood Cancer· July 2017

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Efficacy and Toxicity of Intrathecal Liposomal Cytarabine in First-line Therapy of Childhood Acute Lymphoblastic Leukemia.
Mette Levinsen, Arja Harila-Saari, Kathrine Grell, Olafur Gisli Jonsson, Mervi Taskinen, Jesper Heldrup

J Pediatr Hematol Oncol· November 2016

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Trisomy 8 in pediatric acute myeloid leukemia: A NOPHO-AML study.
Anne Cathrine Lund Laursen, Julie Damgaard Sandahl, Eigil Kjeldsen, Jonas Abrahamsson, Peter Asdahl, Jesper Heldrup

Genes Chromosomes Cancer· September 2016

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Acute Myeloid Leukemia in Adolescents and Young Adults Treated in Pediatric and Adult Departments in the Nordic Countries.
Lovisa Wennström, Pernille Wendtland Edslev, Jonas Abrahamsson, Jan Maxwell Nørgaard, Yngvar Fløisand, Jesper Heldrup

Pediatr Blood Cancer· January 2016

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The applicability of the WHO classification in paediatric AML. A NOPHO-AML study.
Julie D Sandahl, Eigil Kjeldsen, Jonas Abrahamsson, Shau-Yin Ha, Jesper Heldrup

Br J Haematol· June 2015

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The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias.
Anna K Andersson, Jing Ma, Jianmin Wang, Xiang Chen, Amanda Larson Gedman, Jesper Heldrup

Nat Genet· April 2015

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Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity.
Mette Levinsen, Susanne Rosthøj, Ulrikka Nygaard, Jesper Heldrup, Arja Harila-Saari

Cancer Chemother Pharmacol· January 2015

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Ploidy and clinical characteristics of childhood acute myeloid leukemia: A NOPHO-AML study.
Julie Damgaard Sandahl, Eigil Kjeldsen, Jonas Abrahamsson, Shau-Yin Ha, Jesper Heldrup

Genes Chromosomes Cancer· August 2014

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Prognostic implications of mutations in NOTCH1 and FBXW7 in childhood T-ALL treated according to the NOPHO ALL-1992 and ALL-2000 protocols.
Linda Fogelstrand, Anna Staffas, Carina Wasslavik, Helene Sjögren, Stefan Söderhäll, Jesper Heldrup

Pediatr Blood Cancer· March 2014

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Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia.
Magnus Borssén, Lars Palmqvist, Kristina Karrman, Jonas Abrahamsson, Mikael Behrendtz, Jesper Heldrup

PLoS One· January 2014

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Can SLC19A1 80G>A polymorphisms predict risk of extremely delayed MTX excretion after high dose of methotrexate?
Maria Moeller Rasmussen, Regitse Hoejgaard Christensen, Jannie Gregers, Jesper Heldrup, Jacob Nersting

J Pediatr Hematol Oncol· July 2013

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Outcome of poor response paediatric AML using early SCT.
Neval E Wareham, Carsten Heilmann, Jonas Abrahamsson, Erik Forestier, Britt Gustafsson, Jesper Heldrup

Eur J Haematol· March 2013

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Gemtuzumab ozogamicin as postconsolidation therapy does not prevent relapse in children with AML: results from NOPHO-AML 2004.
Henrik Hasle, Jonas Abrahamsson, Erik Forestier, Shau-Yin Ha, Jesper Heldrup

Blood· August 2012

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High dose methotrexate treatment in children with acute lymphoblastic leukaemia may be optimised by a weight-based dose calculation.
Peter Jönsson, Tor Skärby, Jesper Heldrup, Henrik Schrøder, Peter Höglund

Pediatr Blood Cancer· July 2011

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Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry.
Ingrid Thörn, Erik Forestier, Johan Botling, Britt Thuresson, Carina Wasslavik, Jesper Heldrup

Br J Haematol· March 2011

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