Publications by authors named "Jess D Hebert"

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Cas12a mice enable the rapid generation of highly complex tumour genotypes.
Jess D Hebert

Nat Rev Cancer· December 2025

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Functional Mapping of Epigenomic Regulators Uncovers Coordinated Tumor Suppression by the HBO1 and MLL1 Complexes.
Yuning J Tang, Haiqing Xu, Nicholas W Hughes, Paloma Ruiz, Samuel H Kim, Jess D Hebert

Cancer Discov· December 2025

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Efficient and multiplexed somatic genome editing with Cas12a mice.
Jess D Hebert, Haiqing Xu, Yuning J Tang, Paloma A Ruiz, Colin R Detrick

Nat Biomed Eng· November 2025

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Aging represses oncogenic KRAS-driven lung tumorigenesis and alters tumor suppression.
Emily G Shuldiner, Saswati Karmakar, Min K Tsai, Jess D Hebert, Yuning J Tang

Nat Aging· November 2025

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Combinatorial In Vivo Genome Editing Identifies Widespread Epistasis and an Accessible Fitness Landscape During Lung Tumorigenesis.
Jess D Hebert, Yuning J Tang, Márton Szamecz, Laura Andrejka, Steven S Lopez

Mol Biol Evol· February 2025

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A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis.
Emily L Ashkin, Yuning J Tang, Haiqing Xu, King L Hung, Julia A Belk, Jess D Hebert

J Exp Med· January 2025

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A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis.
Emily L Ashkin, Yuning J Tang, Haiqing Xu, King L Hung, Julia Belk, Jess D Hebert

bioRxiv· September 2024

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Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes.
Yuning J Tang, Haiqing Xu, Nicholas W Hughes, Samuel H Kim, Paloma Ruiz, Jess D Hebert

bioRxiv· August 2024

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Efficient and multiplexed somatic genome editing with Cas12a mice.
Jess D Hebert, Haiqing Xu, Yuning J Tang, Paloma A Ruiz, Colin R Detrick

bioRxiv· May 2024

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Aging represses lung tumorigenesis and alters tumor suppression.
Emily G Shuldiner, Saswati Karmakar, Min K Tsai, Jess D Hebert, Yuning J Tang

bioRxiv· May 2024

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Combinatorial genome editing identifies widespread epistasis during lung tumorigenesis.
Jess D Hebert, Yuning J Tang, Laura Andrejka, Steven S Lopez, Dmitri A Petrov

bioRxiv· March 2024

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Dissecting metastasis using preclinical models and methods.
Jess D Hebert, Joel W Neal, Monte M Winslow

Nat Rev Cancer· June 2023

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Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth.
Rui Tang, Emily G Shuldiner, Marcus Kelly, Christopher W Murray, Jess D Hebert

Nat Cell Biol· January 2023

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Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities.
Maryam Yousefi, Gábor Boross, Carly Weiss, Christopher W Murray, Jess D Hebert

Cancer Res· April 2022

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Proteomic Profiling of the ECM of Xenograft Breast Cancer Metastases in Different Organs Reveals Distinct Metastatic Niches.
Jess D Hebert, Samuel A Myers, Alexandra Naba, Genevieve Abbruzzese, John M Lamar

Cancer Res· April 2020

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The scaffold protein IQGAP1 is crucial for extravasation and metastasis.
Jess D Hebert, Chenxi Tian, John M Lamar, Steffen Rickelt, Genevieve Abbruzzese

Sci Rep· February 2020

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Macrophage-Secreted TNFα and TGFβ1 Influence Migration Speed and Persistence of Cancer Cells in 3D Tissue Culture via Independent Pathways.
Ran Li, Jess D Hebert, Tara A Lee, Hao Xing, Alexandra Boussommier-Calleja

Cancer Res· January 2017

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Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells.
Frank A Suprynowicz, Geeta Upadhyay, Ewa Krawczyk, Sarah C Kramer, Jess D Hebert

Proc Natl Acad Sci U S A· December 2012

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The human papillomavirus type 16 E5 oncoprotein translocates calpactin I to the perinuclear region.
Ewa Krawczyk, Frank A Suprynowicz, Jess D Hebert, Christopher M Kamonjoh, Richard Schlegel

J Virol· November 2011

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The human papillomavirus type 16 E5 oncoprotein inhibits epidermal growth factor trafficking independently of endosome acidification.
Frank A Suprynowicz, Ewa Krawczyk, Jess D Hebert, Sawali R Sudarshan, Vera Simic

J Virol· October 2010

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