Publications by authors named "Jesse Bloom"

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Functional and antigenic constraints on the Nipah virus fusion protein.
Brendan B Larsen, Sheri Harari, Risako Gen, Cameron Stewart, David Veesler, Jesse D Bloom

bioRxiv· January 2026

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Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza haemagglutinin.
Timothy C Yu, Caroline Kikawa, Bernadeta Dadonaite, Andrea N Loes, Janet A Englund, Jesse D Bloom

Nat Ecol Evol· December 2025

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Coevolutionary constraints of Zika virus nonstructural protein 5 replication and interferon antagonism activities.
R Blake Richardson, Caroline Kikawa, Amit Garg, Eva Bednarski, Madihah Salim, Jesse D Bloom

bioRxiv· December 2025

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Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapy.
Lutz Gieselmann, Andrew T DeLaitsch, Malena Rohde, Henning Gruell, Christoph Kreer, Jesse D Bloom

Nat Immunol· November 2025

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Spike mutations that affect the function and antigenicity of recent KP.3.1.1-like SARS-CoV-2 variants.
Bernadeta Dadonaite, Sheri Harari, Brendan B Larsen, Lucas Kampman, Alex Harteloo, Jesse D Bloom

J Virol· November 2025

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Cross-neutralizing and potent human monoclonal antibodies against historical and emerging H5Nx influenza viruses.
Alexandra A Abu-Shmais, Gray Freeman, Adrian Creanga, Matthew J Vukovich, Tek Malla, Jesse D Bloom

Nat Microbiol· November 2025

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Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025.
Caroline Kikawa, John Huddleston, Andrea N Loes, Sam A Turner, Jover Lee, Jesse D Bloom

Virus Evol· November 2025

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Fostemsavir analog BMS-818251 has enhanced viral neutralization potency and similar escape mutation profile.
Yen-Ting Lai, Adam S Dingens, Megan DeMouth, Sabrina Helmold Hait, Sijy O'Dell, Jesse D Bloom

Antimicrob Agents Chemother· October 2025

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Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025.
Caroline Kikawa, John Huddleston, Andrea N Loes, Sam A Turner, Jover Lee, Jesse D Bloom

bioRxiv· October 2025

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Combined crystallographic fragment screening and deep mutational scanning enable discovery of Zika virus NS2B-NS3 protease inhibitors.
Xiaomin Ni, R Blake Richardson, Andre Schutzer Godoy, Matteo P Ferla, Caroline Kikawa, Jesse D Bloom

Nat Commun· October 2025

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Germinal center-mediated broadening of B cell responses to SARS-CoV-2 booster immunization.
Sameer Kumar Malladi, Deepika Jaiswal, Baoling Ying, Wafaa B Alsoussi, Tamarand L Darling, Jesse D Bloom

Sci Immunol· October 2025

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Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza hemagglutinin.
Timothy C Yu, Caroline Kikawa, Bernadeta Dadonaite, Andrea N Loes, Janet A Englund, Jesse D Bloom

bioRxiv· September 2025

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Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics.
M Alejandra Tortorici, Annette Choi, Cecily A Gibson, Jimin Lee, Jack T Brown, Jesse D Bloom

Nature· September 2025

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Spike mutations that affect the function and antigenicity of recent KP.3.1.1-like SARS-CoV-2 variants.
Bernadeta Dadonaite, Sheri Harari, Brendan B Larsen, Lucas Kampman, Alex Harteloo, Jesse D Bloom

bioRxiv· September 2025

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Identification of a broad and potent V3 glycan site bNAb targeting an N332 glycan-independent epitope.
Lutz Gieselmann, Andrew T DeLaitsch, Malena Rohde, Caelan Radford, Johanna Worczinski, Jesse D Bloom

bioRxiv· September 2025

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Stabilization of H5 highly pathogenic avian influenza hemagglutinin improves vaccine-elicited neutralizing antibody responses.
Annie Dosey, Bernadeta Dadonaite, Rebecca A Gillespie, Elizabeth M Leaf, Matthew J Vukovich, Jesse D Bloom

bioRxiv· August 2025

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Determinants of human versus mosquito cell entry by the Chikungunya virus envelope proteins.
Xiaohui Ju, William W Hannon, Tomasz Kaszuba, Caelan E Radford, Brendan B Larsen, Jesse D Bloom

bioRxiv· August 2025

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Profiling a large HIV-1 elite neutralizer cohort reveals remarkable CD4bs bNAb for HIV-1 prevention and therapy.
Lutz Gieselmann, Andrew T DeLaitsch, Malena Rohde, Henning Gruell, Christoph Kreer, Jesse D Bloom

bioRxiv· August 2025

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RSV F evolution escapes some monoclonal antibodies but does not strongly erode neutralization by human polyclonal sera.
Cassandra A L Simonich, Teagan E McMahon, Xiaohui Ju, Timothy C Yu, Natalie Brunette, Jesse D Bloom

J Virol· July 2025

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Deep mutational scanning of rabies glycoprotein defines mutational constraint and antibody-escape mutations.
Arjun K Aditham, Caelan E Radford, Caleb R Carr, Naveen Jasti, Neil P King, Jesse D Bloom

Cell Host Microbe· June 2025

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The Data are Insufficient to Confidently Root the SARS-CoV-2 Phylogenetic Tree.
Jesse D Bloom

Mol Biol Evol· June 2025

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The mutation rate of SARS-CoV-2 is highly variable between sites and is influenced by sequence context, genomic region, and RNA structure.
Hugh K Haddox, Georg Angehrn, Luca Sesta, Chris Jennings-Shaffer, Seth D Temple, Jesse D Bloom

Nucleic Acids Res· June 2025

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Replaying germinal center evolution on a quantified affinity landscape.
William S DeWitt, Ashni A Vora, Tatsuya Araki, Jared G Galloway, Tanwee Alkutkar, Jesse D Bloom

bioRxiv· June 2025

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Comprehensive maps of escape mutations from antibodies 10-1074 and 3BNC117 for Envs from two divergent HIV strains.
Caelan E Radford, Jesse D Bloom

J Virol· May 2025

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A broad antibody with enhanced HIV-1 neutralization via bispecific antibody-mediated prepositioning.
Soohyun Kim, Caelan E Radford, Duo Xu, Jianing Zhong, Jonathan Do, Jesse D Bloom

Nat Commun· May 2025

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