Publications by authors named "Lutz Gieselmann"

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Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapy.
Lutz Gieselmann, Andrew T DeLaitsch, Malena Rohde, Henning Gruell, Christoph Kreer

Nat Immunol· November 2025

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Identification of a broad and potent V3 glycan site bNAb targeting an N332 glycan-independent epitope.
Lutz Gieselmann, Andrew T DeLaitsch, Malena Rohde, Caelan Radford, Johanna Worczinski

bioRxiv· September 2025

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Profiling a large HIV-1 elite neutralizer cohort reveals remarkable CD4bs bNAb for HIV-1 prevention and therapy.
Lutz Gieselmann, Andrew T DeLaitsch, Malena Rohde, Henning Gruell, Christoph Kreer

bioRxiv· August 2025

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Immunogenicity of COVID-19 Vaccination in Immunocompromised Patients (Auto-COVID-VACC): Protocol for Multicenter Prospective Noninterventional Study.
Louise Marie Cremer, Ullrich Bethe, Peter Borchmann, Veronica Di Cristanziano, Lutz Gieselmann

JMIR Res Protoc· May 2025

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Seroprevalence of SARS-CoV-2 antibodies in patients with hematological and oncological diseases in early 2024.
Louise M Cremer, Jannik Stemler, Rosanne Sprute, Sebastian Herrmann, Theresa Markus, Lutz Gieselmann

Blood Res· March 2025

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The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm.
Matthias Hamdorf, Thomas Imhof, Ben Bailey-Elkin, Janina Betz, Sebastian J Theobald, Lutz Gieselmann

J Mol Cell Biol· April 2024

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LMP1 and EBNA2 constitute a minimal set of EBV genes for transformation of human B cells.
Jingwei Zhang, Thomas Sommermann, Xun Li, Lutz Gieselmann, Kathrin de la Rosa

Front Immunol· January 2024

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Probabilities of developing HIV-1 bNAb sequence features in uninfected and chronically infected individuals.
Christoph Kreer, Cosimo Lupo, Meryem S Ercanoglu, Lutz Gieselmann, Natanael Spisak

Nat Commun· November 2023

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Dynamics and durability of HIV-1 neutralization are determined by viral replication.
Philipp Schommers, Dae Sung Kim, Maike Schlotz, Christoph Kreer, Ralf Eggeling, Lutz Gieselmann

Nat Med· November 2023

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Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.
Matthias Zehner, Mira Alt, Artem Ashurov, Jory A Goldsmith, Rebecca Spies, Lutz Gieselmann

Immunity· November 2023

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Enhanced SARS-CoV-2 humoral immunity following breakthrough infection builds upon the preexisting memory B cell pool.
Timm Weber, Sabrina Dähling, Svea Rose, Patrick Affeldt, Kanika Vanshylla, Lutz Gieselmann

Sci Immunol· November 2023

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Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning.
Caelan E Radford, Philipp Schommers, Lutz Gieselmann, Katharine H D Crawford, Bernadeta Dadonaite

Cell Host Microbe· July 2023

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Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning.
Caelan E Radford, Philipp Schommers, Lutz Gieselmann, Katharine H D Crawford, Bernadeta Dadonaite

bioRxiv· March 2023

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Pausing methotrexate prevents impairment of Omicron BA.1 and BA.2 neutralisation after COVID-19 booster vaccination.
Elisa Habermann, Lutz Gieselmann, Pinkus Tober-Lau, Jens Klotsche, Fredrik Nils Albach

RMD Open· October 2022

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No substantial preexisting B cell immunity against SARS-CoV-2 in healthy adults.
Meryem Seda Ercanoglu, Lutz Gieselmann, Sabrina Dähling, Nareshkumar Poopalasingam, Susanne Detmer

iScience· March 2022

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Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization.
Timm Weber, Julian Potthoff, Sven Bizu, Maurice Labuhn, Leona Dold, Lutz Gieselmann

Immunity· February 2022

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Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers.
Kanika Vanshylla, Chengcheng Fan, Marie Wunsch, Nareshkumar Poopalasingam, Matthijs Meijers, Lutz Gieselmann

Cell Host Microbe· January 2022

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Evaluation of a Rapid Antigen Test To Detect SARS-CoV-2 Infection and Identify Potentially Infectious Individuals.
Michael Korenkov, Nareshkumar Poopalasingam, Matthias Madler, Kanika Vanshylla, Ralf Eggeling, Lutz Gieselmann

J Clin Microbiol· August 2021

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Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort study.
Max Augustin, Philipp Schommers, Melanie Stecher, Felix Dewald, Lutz Gieselmann

Lancet Reg Health Eur· July 2021

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Effective high-throughput isolation of fully human antibodies targeting infectious pathogens.
Lutz Gieselmann, Christoph Kreer, Meryem Seda Ercanoglu, Nathalie Lehnen, Matthias Zehner

Nat Protoc· July 2021

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Kinetics and correlates of the neutralizing antibody response to SARS-CoV-2 infection in humans.
Kanika Vanshylla, Veronica Di Cristanziano, Franziska Kleipass, Felix Dewald, Philipp Schommers, Lutz Gieselmann

Cell Host Microbe· June 2021

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Development and characterization of an indirect ELISA to detect SARS-CoV-2 spike protein-specific antibodies.
Verena Krähling, Sandro Halwe, Cornelius Rohde, Dirk Becker, Susanne Berghöfer, Lutz Gieselmann

J Immunol Methods· March 2021

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Correction: Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV.
Sebastian J Theobald, Christoph Kreer, Sahamoddin Khailaie, Agnes Bonifacius, Britta Eiz-Vesper, Lutz Gieselmann

PLoS Pathog· March 2021

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Evaluation of a New Spike (S)-Protein-Based Commercial Immunoassay for the Detection of Anti-SARS-CoV-2 IgG.
Kirsten Alexandra Eberhardt, Felix Dewald, Eva Heger, Lutz Gieselmann, Kanika Vanshylla

Microorganisms· March 2021

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Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients.
Christoph Kreer, Matthias Zehner, Timm Weber, Meryem S Ercanoglu, Lutz Gieselmann

Cell· September 2020

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