Publications by authors named "Jesse Engreitz"

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An expanded registry of candidate cis-regulatory elements.
Jill E Moore, Henry E Pratt, Kaili Fan, Nishigandha Phalke, Jonathan Fisher, Jesse M Engreitz

Nature· January 2026

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The IGVF catalog-from genetic variation to function.
Daofeng Li, Shane Liu, Pedro R Assis, Mingjie Li, Shengcheng Dong, Jesse M Engreitz

Nucleic Acids Res· December 2025

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Epigenomic landscape of single vascular cells reflects developmental origin and disease risk loci.
Chad S Weldy, Soumya Kundu, João Monteiro, Wenduo Gu, Albert J Pedroza, Jesse Engreitz

Mol Syst Biol· November 2025

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Deep learning the dynamic regulatory sequence code of cardiac organoid differentiation.
Eyal Metzl-Raz, Ryan Zhao, Salil Deshpande, Jackson Powell, Elizabeth G Porter, Jesse M Engreitz

bioRxiv· October 2025

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Enhancer-targeting CRISPR screens at coronary artery disease loci suggest shared mechanisms of disease risk.
Markus Ramste, Chad Weldy, Soumya Kundu, Quanyi Zhao, Daniel Li, Jesse M Engreitz

medRxiv· September 2025

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Disease-linked regulatory DNA variants and homeostatic transcription factors in epidermis.
Douglas F Porter, Robin M Meyers, Weili Miao, David L Reynolds, Audrey W Hong, Jesse M Engreitz

Nat Commun· September 2025

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An unbiased survey of distal element-gene regulatory interactions with direct-capture targeted Perturb-seq.
Judhajeet Ray, Evelyn Jagoda, Maya U Sheth, James Galante, Dulguun Amgalan, Jesse M Engreitz

bioRxiv· September 2025

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Targeting RUNX1 in Macrophages Facilitates Cardiac Recovery.
Junedh M Amrute, Ada Zhu, Yun-Ling Pai, Melissa Hector-Greene, Yuqian An, Jesse M Engreitz

bioRxiv· July 2025

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Rewriting regulatory DNA to dissect and reprogram gene expression.
Gabriella E Martyn, Michael T Montgomery, Hank Jones, Katherine Guo, Benjamin R Doughty, Jesse M Engreitz

Cell· June 2025

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Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma.
Ashwin R Iyer, Aishwarya Gurumurthy, Shih-Chun A Chu, Rohan Kodgule, Athalee R Aguilar, Jesse M Engreitz

Blood Cancer Discov· May 2025

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The epigenomic landscape of single vascular cells reflects developmental origin and identifies disease risk loci.
Chad S Weldy, Soumya Kundu, João Monteiro, Wenduo Gu, Albert J Pedroza, Jesse Engreitz

bioRxiv· May 2025

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Endothelial cell-related genetic variants identify LDL cholesterol-sensitive individuals who derive greater benefit from aggressive lipid lowering.
Nicholas A Marston, Frederick K Kamanu, Giorgio E M Melloni, Gavin Schnitzler, Aaron Hakim, Jesse M Engreitz

Nat Med· March 2025

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High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension.
Tsutomu Shinohara, Jan-Renier Moonen, Yoon Hong Chun, Yannick C Lee-Yow, Kenichi Okamura, Jesse M Engreitz

Arterioscler Thromb Vasc Biol· February 2025

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MorPhiC Consortium: towards functional characterization of all human genes.
Mazhar Adli, Laralynne Przybyla, Tony Burdett, Paul W Burridge, Pilar Cacheiro, Jesse M Engreitz

Nature· February 2025

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Selective Enhancer Gain-of-Function Deregulates MYC Expression in Multiple Myeloma.
Mahshid Rahmat, Kendell Clement, Jean-Baptiste Alberge, Romanos Sklavenitis-Pistofidis, Rohan Kodgule, Jesse M Engreitz

Cancer Res· December 2024

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Small-cohort GWAS discovery with AI over massive functional genomics knowledge graph.
Kexin Huang, Tony Zeng, Soner Koc, Alexandra Pettet, Jingtian Zhou, Jesse M Engreitz

medRxiv· December 2024

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An Expanded Registry of Candidate cis-Regulatory Elements for Studying Transcriptional Regulation.
Jill E Moore, Henry E Pratt, Kaili Fan, Nishigandha Phalke, Jonathan Fisher, Jesse Engreitz

bioRxiv· December 2024

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Mapping enhancer-gene regulatory interactions from single-cell data.
Maya U Sheth, Wei-Lin Qiu, X Rosa Ma, Andreas R Gschwind, Evelyn Jagoda, Jesse M Engreitz

bioRxiv· November 2024

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Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart.
X Rosa Ma, Stephanie D Conley, Michael Kosicki, Danila Bredikhin, Ran Cui, Jesse M Engreitz

medRxiv· November 2024

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Single cell variant to enhancer to gene map for coronary artery disease.
Junedh M Amrute, Paul C Lee, Ittai Eres, Chang Jie Mick Lee, Andrea Bredemeyer, Jesse M Engreitz

medRxiv· November 2024

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Genetic and functional analysis of Raynaud's syndrome implicates loci in vasculature and immunity.
Anniina Tervi, Markus Ramste, Erik Abner, Paul Cheng, Jacqueline M Lane, Jesse M Engreitz

Cell Genom· September 2024

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Cohesin-mediated 3D contacts tune enhancer-promoter regulation.
Philine Guckelberger, Benjamin R Doughty, Glen Munson, Suhas S P Rao, Yingxuan Tan, Jesse M Engreitz

bioRxiv· July 2024

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Multicenter integrated analysis of noncoding CRISPRi screens.
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Jesse M Engreitz

Nat Methods· April 2024

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Convergence of coronary artery disease genes onto endothelial cell programs.
Gavin R Schnitzler, Helen Kang, Shi Fang, Ramcharan S Angom, Vivian S Lee-Kim, Jesse M Engreitz

Nature· February 2024

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High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension.
Tsutomu Shinohara, Jan-Renier Moonen, Yoon Hong Chun, Yannick C Lee-Yow, Kenichi Okamura, Jesse M Engreitz

bioRxiv· February 2024

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