Publications by authors named "Jessica Able"

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Sulfonamides as Selective Na1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity.
Russell F Graceffa, Alessandro A Boezio, Jessica Able, Steven Altmann, Loren M Berry

J Med Chem· July 2017

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Correction to "Sulfonamides as Selective Na1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable Target Engagement".
Isaac E Marx, Thomas A Dineen, Jessica Able, Christiane Bode, Howard Bregman

ACS Med Chem Lett· March 2017

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Sulfonamides as Selective Na1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement.
Isaac E Marx, Thomas A Dineen, Jessica Able, Christiane Bode, Howard Bregman

ACS Med Chem Lett· December 2016

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AMG 580: a novel small molecule phosphodiesterase 10A (PDE10A) positron emission tomography tracer.
Hang Chen, Dianna Lester-Zeiner, Jianxia Shi, Silke Miller, Charlie Glaus, Jessica Able

J Pharmacol Exp Ther· February 2015

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Discovery of clinical candidate 1-(4-(3-(4-(1H-benzo[d]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)ethanone (AMG 579), a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A).
Essa Hu, Ning Chen, Matthew P Bourbeau, Paul E Harrington, Kaustav Biswas, Jessica Able

J Med Chem· August 2014

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Discovery of Novel Imidazo[4,5-b]pyridines as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A).
Essa Hu, Kristin Andrews, Samer Chmait, Xiaoning Zhao, Carl Davis, Jessica Able

ACS Med Chem Lett· June 2014

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Omega-3 fatty acid deficient male rats exhibit abnormal behavioral activation in the forced swim test following chronic fluoxetine treatment: association with altered 5-HT1A and alpha2A adrenergic receptor expression.
Jessica A Able, Yanhong Liu, Ronald Jandacek, Therese Rider, Patrick Tso

J Psychiatr Res· March 2014

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Omega-3 fatty acid deficiency does not alter the effects of chronic fluoxetine treatment on central serotonin turnover or behavior in the forced swim test in female rats.
Robert K McNamara, Jessica A Able, Yanhong Liu, Ronald Jandacek, Therese Rider

Pharmacol Biochem Behav· December 2013

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Rapid identification of a novel small molecule phosphodiesterase 10A (PDE10A) tracer.
Essa Hu, Ji Ma, Christopher Biorn, Dianna Lester-Zeiner, Robert Cho, Jessica Able

J Med Chem· May 2012

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Effect of chronic fluoxetine treatment on male and female rat erythrocyte and prefrontal cortex fatty acid composition.
Robert K McNamara, Jessica A Able, Therese Rider, Patrick Tso, Ronald Jandacek

Prog Neuropsychopharmacol Biol Psychiatry· October 2010

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Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging study.
Robert K McNamara, Jessica Able, Ronald Jandacek, Therese Rider, Patrick Tso

Am J Clin Nutr· April 2010

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Gender differences in rat erythrocyte and brain docosahexaenoic acid composition: role of ovarian hormones and dietary omega-3 fatty acid composition.
Robert K McNamara, Jessica Able, Ronald Jandacek, Therese Rider, Patrick Tso

Psychoneuroendocrinology· May 2009

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Perinatal n-3 fatty acid deficiency selectively reduces myo-inositol levels in the adult rat PFC: an in vivo (1)H-MRS study.
Robert K McNamara, Jessica Able, Ronald Jandacek, Therese Rider, Patrick Tso

J Lipid Res· March 2009

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Omega-3 fatty acid deficiency during perinatal development increases serotonin turnover in the prefrontal cortex and decreases midbrain tryptophan hydroxylase-2 expression in adult female rats: dissociation from estrogenic effects.
Robert K McNamara, Jessica Able, Yanhong Liu, Ronald Jandacek, Therese Rider

J Psychiatr Res· March 2009

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Chronic risperidone treatment preferentially increases rat erythrocyte and prefrontal cortex omega-3 fatty acid composition: evidence for augmented biosynthesis.
Robert K McNamara, Jessica A Able, Ronald Jandacek, Therese Rider, Patrick Tso

Schizophr Res· February 2009

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Inbred C57BL/6J and DBA/2J mouse strains exhibit constitutive differences in regional brain fatty acid composition.
Robert K McNamara, Jessica Able, Ronald Jandacek, Therese Rider, Patrick Tso

Lipids· January 2009

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(+/-)-3,4-Methylenedioxymethamphetamine treatment in adult rats impairs path integration learning: a comparison of single vs once per week treatment for 5 weeks.
Matthew R Skelton, Jessica A Able, Curtis E Grace, Nicole R Herring, Tori L Schaefer

Neuropharmacology· December 2008

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WITHDRAWN: Published in error by the publisher: Constitutive differences in regional brain fatty acid content of inbred C57BL/6J and DBA/2J mouse strains.
Robert K McNamara, Jessica Able, Ronald Jandacek, Therese Rider, Patrick Tso

J Lipid Res· May 2008

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3,4-Methylenedioxymethamphetamine in adult rats produces deficits in path integration and spatial reference memory.
Jessica A Able, Gary A Gudelsky, Charles V Vorhees, Michael T Williams

Biol Psychiatry· June 2006

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3,4-Methylenedioxymethamphetamine administration on postnatal day 11 in rats increases pituitary-adrenal output and reduces striatal and hippocampal serotonin without altering SERT activity.
Michael T Williams, Tori L Schaefer, Lisa A Ehrman, Jessica A Able, Gary A Gudelsky

Brain Res· March 2005

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