Publications by authors named "Jessica D Rosarda"

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Pharmacological targeting of RIG-I can selectively activate the integrated stress response.
Caroline A Cuoco, Wen Ren, Kelsey R Baron, Sakina Gologo, Valerie Perea, Jessica D Rosarda

Sci Adv· October 2025

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Identification of a Selective Pharmacologic IRE1/XBP1s Activator with Enhanced Tissue Exposure.
Jie Sun, Kyunga Lee, Sergei Kutseikin, Adrian Guerrero, Bibiana Rius, Jessica D Rosarda

ACS Chem Biol· May 2025

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Pharmacologic Targeting of PDIA1 Inhibits NLRP3 Inflammasome Assembly and Activation.
Jessica D Rosarda, Caroline R Stanton, Emily B Chen, Michael J Bollong, R Luke Wiseman

Isr J Chem· December 2024

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White matter damage and degeneration in traumatic brain injury.
Regina C Armstrong, Genevieve M Sullivan, Daniel P Perl, Jessica D Rosarda, Kryslaine L Radomski

Trends Neurosci· September 2024

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Metabolically activated proteostasis regulators that protect against erastin-induced ferroptosis.
Gabriel M Kline, Nicole Madrazo, Christian M Cole, Meera Pannikkat, Michael J Bollong, Jessica D Rosarda

RSC Chem Biol· August 2024

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Mapping stress-responsive signaling pathways induced by mitochondrial proteostasis perturbations.
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman

Mol Biol Cell· May 2024

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Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly.
Caroline Stanton, Jie Sun, Kayla Nutsch, Jessica D Rosarda, Thu Nguyen

ACS Chem Biol· February 2024

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Mapping Stress-Responsive Signaling Pathways Induced by Mitochondrial Proteostasis Perturbations.
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman

bioRxiv· February 2024

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Pharmacologic activation of a compensatory integrated stress response kinase promotes mitochondrial remodeling in PERK-deficient cells.
Valerie Perea, Kelsey R Baron, Vivian Dolina, Giovanni Aviles, Grace Kim, Jessica D Rosarda

Cell Chem Biol· December 2023

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Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity.
Jessica D Rosarda, Sarah Giles, Sarah Harkins-Perry, Elizabeth A Mills, Martin Friedlander

Nat Commun· July 2023

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Covalent targeting as a common mechanism for inhibiting NLRP3 inflammasome assembly.
Caroline Stanton, Jie Sun, Kayla Nutsch, Jessica D Rosarda, Thu Nguyen

bioRxiv· June 2023

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Pharmacologic Activation of a Compensatory Integrated Stress Response Kinase Promotes Mitochondrial Remodeling in PERK-deficient Cells.
Valerie Perea, Kelsey R Baron, Vivian Dolina, Giovanni Aviles, Jessica D Rosarda

bioRxiv· May 2023

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Metabolically Activated Proteostasis Regulators Protect against Glutamate Toxicity by Activating NRF2.
Jessica D Rosarda, Kelsey R Baron, Kayla Nutsch, Gabriel M Kline, Caroline Stanton

ACS Chem Biol· December 2021

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Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease.
Richard M Giadone, Derek C Liberti, Taylor M Matte, Jessica D Rosarda, Celia Torres-Arancivia

Stem Cell Reports· August 2020

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Proteostasis and Beyond: ATF6 in Ischemic Disease.
Christopher C Glembotski, Jessica D Rosarda, R Luke Wiseman

Trends Mol Med· June 2019

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A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics.
Richard M Giadone, Jessica D Rosarda, Prithvi Reddy Akepati, Arianne C Thomas, Batbold Boldbaatar

Amyloid· September 2018

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