Publications by authors named "Jessica Downs"

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The CIP2A-TOPBP1 axis facilitates mitotic DNA repair via MiDAS and MMEJ.
Peter R Martin, Jadwiga Nieminuszczy, Zuza Kozik, Nihal Jakub, Szymon Kowalski, Jessica A Downs

Nat Commun· November 2025

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ARID1A stabilizes non-homologous end joining factors at DNA breaks induced by the G4 ligand pyridostatin.
Susana Simões-Sousa, Noa Amin, Karen A Lane, Alison Harrod, Malin Pedersen, Jessica A Downs

Cell Rep· September 2025

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PBRM1 directs PBAF to pericentromeres and protects centromere integrity.
Karen A Lane, Alison Harrod, Lillian Wu, Theodoros I Roumeliotis, Hugang Feng, Jessica A Downs

Nat Commun· February 2025

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Chromatin remodeling and spatial concerns in DNA double-strand break repair.
Jessica A Downs, Susan M Gasser

Curr Opin Cell Biol· October 2024

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Defects in DNA damage responses in SWI/SNF mutant cells and their impact on immune responses.
Katheryn A G Begg, Hanna Braun, Nagham Ghaddar, Lillian Wu, Jessica A Downs

DNA Repair (Amst)· January 2024

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A recombinant approach for stapled peptide discovery yields inhibitors of the RAD51 recombinase.
Teodors Pantelejevs, Pedro Zuazua-Villar, Oliwia Koczy, Andrew J Counsell, Stephen J Walsh, Jessica A Downs

Chem Sci· December 2023

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PBAF loss leads to DNA damage-induced inflammatory signaling through defective G2/M checkpoint maintenance.
Hugang Feng, Karen A Lane, Theodoros I Roumeliotis, Penny A Jeggo, Navita Somaiah, Jessica A Downs

Genes Dev· July 2022

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Aneuploidy tolerance caused by BRG1 loss allows chromosome gains and recovery of fitness.
Federica Schiavoni, Pedro Zuazua-Villar, Theodoros I Roumeliotis, Graeme Benstead-Hume, Mercedes Pardo, Jessica A Downs

Nat Commun· April 2022

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Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats.
Laurens H Lindenburg, Teodors Pantelejevs, Fabrice Gielen, Pedro Zuazua-Villar, Maren Butz, Jessica A Downs

Proc Natl Acad Sci U S A· November 2021

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Increased Upper Arm Length and Loading Rate Identified as Potential Risk Factors for Injury in Youth Baseball Pitchers.
Jessica L Downs, Kyle W Wasserberger, Jeff W Barfield, Michael G Saper, Gretchen D Oliver

Am J Sports Med· September 2021

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Comparison of Pelvis and Trunk Kinematics Between Youth and Collegiate Windmill Softball Pitchers.
Kyle W Wasserberger, Kenzie B Friesen, Jessica L Downs, Nicole M Bordelon, Gretchen D Oliver

Orthop J Sports Med· August 2021

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PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer.
Roman M Chabanon, Daphné Morel, Thomas Eychenne, Léo Colmet-Daage, Ilirjana Bajrami, Jessica A Downs

Cancer Res· June 2021

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Histone isoforms and the oncohistone code.
Andrew Flaus, Jessica A Downs, Tom Owen-Hughes

Curr Opin Genet Dev· April 2021

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Biceps Tendon Changes and Pitching Mechanics in Youth Softball Pitchers.
Gretchen D Oliver, Jessica L Downs, Kenzie B Friesen, Michael G Saper, Adam W Anz

Int J Sports Med· March 2021

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Kinematic Differences Exist Between the Fastball, Changeup, Curveball, and Dropball Pitch Types in Collegiate Softball Pitchers.
Jessica L Downs, Nicole M Bordelon, Kenzie B Friesen, David M Shannon, Gretchen D Oliver

Am J Sports Med· March 2021

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Hip Range of Motion and Strength and Energy Flow During Windmill Softball Pitching.
Gretchen D Oliver, Kyle Wasserberger, Anne de Swart, Kenzie Friesen, Jessica Downs

J Athl Train· March 2021

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Differential and longitudinal immune gene patterns associated with reprogrammed microenvironment and viral mimicry in response to neoadjuvant radiotherapy in rectal cancer.
Anna Wilkins, Elisa Fontana, Gift Nyamundanda, Chanthirika Ragulan, Yatish Patil, Jessica Downs

J Immunother Cancer· March 2021

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TP53 modulates radiotherapy fraction size sensitivity in normal and malignant cells.
Selvakumar Anbalagan, Cecilia Ström, Jessica A Downs, Penny A Jeggo, David McBay

Sci Rep· March 2021

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Influence of a Pre-throwing Protocol on Range of Motion and Strength in Baseball Athletes.
Jessica Downs, Kyle Wasserberger, Gretchen D Oliver

Int J Sports Med· February 2021

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DESCRIPTIVE PROFILE OF SHOULDER RANGE OF MOTION AND STRENGTH IN YOUTH ATHLETES PARTICIPATING IN OVERHEAD SPORTS.
Gretchen D Oliver, Jessica L Downs, Germanna M Barbosa, Paula R Camargo

Int J Sports Phys Ther· December 2020

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CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.
Magdalena B Rother, Stefania Pellegrino, Rebecca Smith, Marco Gatti, Cornelia Meisenberg, Jessica A Downs

Nat Commun· November 2020

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The role of the SWI/SNF chromatin remodelling complex in the response to DNA double strand breaks.
Alison Harrod, Karen A Lane, Jessica A Downs

DNA Repair (Amst)· September 2020

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Glenohumeral external rotation weakness partially accounts for increased humeral rotation torque in youth baseball pitchers.
Kyle W Wasserberger, Jeff W Barfield, Jessica L Downs, Gretchen D Oliver

J Sci Med Sport· April 2020

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Effects of a Simulated Game on Pitching Kinematics in Youth Softball Pitcher.
Jessica Downs, Kenzie Friesen, Adam W Anz, Jeffrey R Dugas, James R Andrews

Int J Sports Med· March 2020

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Glenohumeral and Hip Range of Motion in Youth Softball Athletes.
Kenzie Friesen, Jessica Downs, Kyle Wasserberger, David Shannon, Gretchen D Oliver

Int J Sports Med· January 2020

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