Publications by authors named "Jessica Kilgore"

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Tryptophan metabolite atlas uncovers organ, age, and sex-specific variations.
Lizbeth Perez-Castro, Afshan F Nawas, Jessica A Kilgore, Pedro A S Nogueira, M Carmen Lafita-Navarro

FEBS Open Bio· September 2025

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Sustained Release of Antifibrotic Nintedanib from Polymer Microparticles Reduces Dosing Frequency While Reducing Inflammation in Murine Idiopathic Pulmonary Fibrosis.
Emmanuel Einyat Opolot, Filip Goshevski, Rahul Chaudhary, Jessica A Kilgore, Noelle S Williams

Ann Biomed Eng· July 2025

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Thioredoxin Reductase 1 inhibition triggers ferroptosis in KRAS-independent lung cancers.
Cristina Andreani, Caterina Bartolacci, Margherita Melegari, Nicola Sargentoni, Lorenzo Luciani, Jessica Kilgore

bioRxiv· July 2025

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Tryptophan metabolite atlas uncovers organ, age, and sex-specific variations.
Lizbeth Perez-Castro, Afshan F Nawas, Jessica A Kilgore, Roy Garcia, M Carmen Lafita-Navarro

bioRxiv· December 2024

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Endogenous EWSR1-FLI1 degron alleles enable control of fusion oncoprotein expression in tumor cell lines and xenografts.
James H McGinnis, Alberto Bremauntz Enriquez, Florentina Vandiver, Xin Bai, Jiwoong Kim, Jessica Kilgore

bioRxiv· October 2024

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Hippocampal Availability of the α7 Nicotinic Acetylcholine Receptor in Recent-Onset Psychosis.
Nicole R Wong, Leah H Rubin, Courtney K Harrington, Katelyn R Jenkins, Laura K Shinehouse, Jessica J Kilgore

JAMA Netw Open· August 2024

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Targeting of neuroblastoma cells through Kynurenine-AHR pathway inhibition.
Igor Lopes Dos Santos, Michael Mitchell, Pedro A S Nogueira, M Carmen Lafita-Navarro, Lizbeth Perez-Castro, Jessica A Kilgore

FEBS J· May 2024

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Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis.
Niranjan Venkateswaran, Roy Garcia, M Carmen Lafita-Navarro, Yi-Heng Hao, Lizbeth Perez-Castro, Jessica A Kilgore

Nat Commun· May 2024

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Augmented Concentration of Isopentyl-Deoxynyboquinone in Tumors Selectively Kills NAD(P)H Quinone Oxidoreductase 1-Positive Cancer Cells through Programmed Necrotic and Apoptotic Mechanisms.
Jiangwei Wang, Xiaolin Su, Lingxiang Jiang, Matthew W Boudreau, Lindsay E Chatkewitz, Jessica A Kilgore

Cancers (Basel)· December 2023

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Orthogonal Hydroxyl Functionalization of cGAMP Confers Metabolic Stability and Enables Antibody Conjugation.
Yong Lu, Lin You, Liping Li, Jessica A Kilgore, Shun Liu

ACS Cent Sci· December 2023

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Imaging Brain Injury in Former National Football League Players.
Leah H Rubin, Yong Du, Shannon Eileen Sweeney, Riley O'Toole, Cykyra L Thomas, Jessica J Kilgore

JAMA Netw Open· October 2023

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Development of a biomarker to monitor target engagement after treatment with dihydroorotate dehydrogenase inhibitors.
Michael A Pontikos, Christopher Leija, Zhiyu Zhao, Xiaoyu Wang, Jessica Kilgore

Biochem Pharmacol· October 2022

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KP372-1-Induced AKT Hyperactivation Blocks DNA Repair to Synergize With PARP Inhibitor Rucaparib Inhibiting FOXO3a/GADD45α Pathway.
Lingxiang Jiang, Yingchun Liu, Xiaolin Su, Jiangwei Wang, Ye Zhao, Jessica A Kilgore

Front Oncol· September 2022

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Regional amyloid correlates of cognitive performance in ageing and mild cognitive impairment.
Daniel A Stevens, Clifford I Workman, Hiroto Kuwabara, Meryl A Butters, Alena Savonenko, Jessica Kilgore

Brain Commun· February 2022

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Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling.
Jugal Mohapatra, Kyuto Tashiro, Ryan L Beckner, Jorge Sierra, Jessica A Kilgore

Elife· December 2021

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Polymer Microparticles Prolong Delivery of the 15-PGDH Inhibitor SW033291.
Alan B Dogan, Nathan A Rohner, Julianne N P Smith, Jessica A Kilgore, Noelle S Williams

Pharmaceutics· December 2021

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Reducing acetylated tau is neuroprotective in brain injury.
Min-Kyoo Shin, Edwin Vázquez-Rosa, Yeojung Koh, Matasha Dhar, Kalyani Chaubey, Jessica A Kilgore

Cell· May 2021

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Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells.
M Carmen Lafita-Navarro, Niranjan Venkateswaran, Jessica A Kilgore, Suman Kanji, Jungsoo Han

PLoS Genet· November 2020

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MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer.
Niranjan Venkateswaran, M Carmen Lafita-Navarro, Yi-Heng Hao, Jessica A Kilgore, Lizbeth Perez-Castro

Genes Dev· September 2019

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NQO1-dependent, Tumor-selective Radiosensitization of Non-small Cell Lung Cancers.
Edward A Motea, Xiumei Huang, Naveen Singh, Jessica A Kilgore, Noelle S Williams

Clin Cancer Res· April 2019

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Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors.
Xiumei Huang, Edward A Motea, Zachary R Moore, Jun Yao, Ying Dong, Jessica A Kilgore

Cancer Cell· December 2016

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Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy.
Xinpeng Ma, Xiumei Huang, Zachary Moore, Gang Huang, Jessica A Kilgore

J Control Release· February 2015

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Identification of DNMT1 selective antagonists using a novel scintillation proximity assay.
Jessica A Kilgore, Xinlin Du, Lisa Melito, Shuguang Wei, Changguang Wang

J Biol Chem· July 2013

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An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis.
Xiumei Huang, Ying Dong, Erik A Bey, Jessica A Kilgore, Joseph S Bair

Cancer Res· June 2012

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Specific inhibition of mitochondrial oxidative stress suppresses inflammation and improves cardiac function in a rat pneumonia-related sepsis model.
Qun S Zang, Hesham Sadek, David L Maass, Bobbie Martinez, Lisha Ma, Jessica A Kilgore

Am J Physiol Heart Circ Physiol· May 2012

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