Publications by authors named "Jessica N Hatton"

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A quantitative, Bayesian-informed approach to gene-specific variant classification: Updated Expert Panel recommendations improve classification of TP53 germline variants for Li-Fraumeni syndrome.
Cristina Fortuno, Megan N Frone, Jessica Mester, Miguel de la Hoya, Phuong L Mai, Jessica N Hatton

Genome Med· October 2025

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Clinicopathologic Features, Management, and Outcomes Of Pediatric CRTC1::TRIM11 and MED15::ATF1 Tumors With Spitzoid Morphology: A Case Series.
Michael R Sargen, Madeline H Fitzhugh, Jennifer S Ko, Allison G Close, Sara C Horton, Jessica N Hatton

Pediatr Blood Cancer· August 2025

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Prognostic Significance of Germline Pathogenic or Likely Pathogenic Variants in Outcomes of Ovarian Sertoli-Leydig Cell Tumor.
Alexander T Nelson, Dave Watson, Kenneth S Chen, Damon R Olson, Jennifer N Stall, Jessica N Hatton

JCO Precis Oncol· April 2025

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DICER1-Related Tumor Predisposition: Identification of At-risk Individuals and Recommended Surveillance Strategies.
Kris Ann P Schultz, Alexander T Nelson, Paige H R Mallinger, Anne K Harris, Junne Kamihara, Jessica N Hatton

Clin Cancer Res· December 2024

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Characterization of sarcoma topography in Li-Fraumeni syndrome.
Karin J Brockman, Mone't B Thompson, Lisa Mirabello, Sharon A Savage, Ashkan Malayeri, Jessica N Hatton

Front Oncol· November 2024

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Characterizing Lung Cancer in Li-Fraumeni Syndrome.
Jessica N Hatton, John Kucera, Kenneth P Seastedt, Kelvin César de Andrade, Sharon A Savage

JAMA Oncol· September 2024

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A genome-first approach to characterize DICER1 pathogenic variant prevalence, penetrance and cancer, thyroid, and other phenotypes in 2 population-scale cohorts.
Jung Kim, Jeremy Haley, Jessica N Hatton, Uyenlinh L Mirshahi, H Shanker Rao

Genet Med Open· April 2024

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Spectrum and Excess Risk of Gastrointestinal Tumors in Li-Fraumeni Syndrome.
Jessica N Hatton, Kelvin C de Andrade, Megan N Frone, Sharon A Savage, Payal P Khincha

Clin Gastroenterol Hepatol· March 2024

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Genome-first approach of the prevalence and cancer phenotypes of pathogenic or likely pathogenic germline TP53 variants.
Kelvin C de Andrade, Natasha T Strande, Jung Kim, Jeremy S Haley, Jessica N Hatton

HGG Adv· January 2024

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Specifications of the ACMG/AMP Variant Classification Guidelines for Germline Variant Curation.
Jessica N Hatton, Megan N Frone, Hannah C Cox, Stephanie B Crowley, Susan Hiraki

Hum Mutat· December 2023

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Estimated Prevalence, Tumor Spectrum, and Neurofibromatosis Type 1-Like Phenotype of CDKN2A-Related Melanoma-Astrocytoma Syndrome.
Michael R Sargen, Jung Kim, Thomas P Potjer, Mary E Velthuizen, Arelis E Martir-Negron, Jessica N Hatton

JAMA Dermatol· October 2023

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Intronic Germline Variants in Patients With Sertoli-Leydig Cell Tumor.
Claudette R Fraire, Paige R Mallinger, Jessica N Hatton, Jung Kim, David S Dickens

JCO Precis Oncol· September 2023

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Impact of Transcript (p16/p14ARF) Alteration on Cancer Risk in CDKN2A Germline Pathogenic Variant Carriers.
Michael R Sargen, Hildur Helgadottir, Xiaohong R Yang, Mark Harland, Jessica N Hatton

JNCI Cancer Spectr· November 2022

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Spectrum and Incidence of Skin Cancer among Individuals with Li-Fraumeni Syndrome.
Jessica N Hatton, Michael R Sargen, Megan N Frone, Kelvin C de Andrade, Sharon A Savage

J Invest Dermatol· September 2022

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The TP53 Database: transition from the International Agency for Research on Cancer to the US National Cancer Institute.
Kelvin César de Andrade, Elaine E Lee, Elise M Tookmanian, Chimene A Kesserwan, James J Manfredi, Jessica N Hatton

Cell Death Differ· May 2022

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Cancer incidence, patterns, and genotype-phenotype associations in individuals with pathogenic or likely pathogenic germline TP53 variants: an observational cohort study.
Kelvin César de Andrade, Payal P Khincha, Jessica N Hatton, Megan N Frone, Talia Wegman-Ostrosky

Lancet Oncol· December 2021

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