Publications by authors named "Jessica Root"

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genotypes differentially remodel the astrocytic lipid droplet-associated proteome to shape lipid droplet dynamics.
Carla Cuní-López, Jessica T Root, Ying Hao, Isabelle Kowal, Niek Blomberg

bioRxiv· August 2025

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Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4.
Roxan A Stephenson, Jordy Sepulveda, Kory R Johnson, Adrian Lita, Jaanam Gopalakrishnan, Jessica T Root

Cell Rep· July 2025

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Blood-based proteomic profiling identifies OSMR as a novel biomarker of AML outcomes.
Patrick K Reville, Bofei Wang, Jennifer Marvin-Peek, Bin Yuan, Yu-An Kuo, Jessica Root

Blood· June 2025

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Multimodal spatial proteomic profiling in acute myeloid leukemia.
Christopher P Ly, Ivo Veletic, Christopher D Pacheco, Enes Dasdemir, Fatima Z Jelloul, Jessica L Root

NPJ Precis Oncol· May 2025

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Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency.
Jessica Root, Anarmaa Mendsaikhan, Georgia Taylor, Paola Merino, Srijita Nandy

Cell Rep· December 2024

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Triglyceride metabolism controls inflammation and -associated disease states in microglia.
Roxan A Stephenson, Kory R Johnson, Linling Cheng, Linda G Yang, Jessica T Root

bioRxiv· April 2024

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Single-Cell CD4 and CD8 T-Cell Secretome Profiling Reveals Temporal and Niche Differences in Acute Myeloid Leukemia Following Immune Checkpoint Blockade Therapy.
Jessica L Root, Poonam N Desai, Christopher Ly, Bofei Wang, Fatima Zahra Jelloul

Cancer Res Commun· March 2024

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Single-Cell Profiling of CD8+ T Cells in Acute Myeloid Leukemia Reveals a Continuous Spectrum of Differentiation and Clonal Hyperexpansion.
Poonam N Desai, Bofei Wang, Andre Fonseca, Pamella Borges, Fatima Zahra Jelloul, Jessica Root

Cancer Immunol Res· May 2023

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Granulins rescue inflammation, lysosome dysfunction, and neuropathology in a mouse model of progranulin deficiency.
Jessica Root, Anarmaa Mendsaikhan, Srijita Nandy, Georgia Taylor, Minzheng Wang

bioRxiv· April 2023

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Allele-specific cis-regulatory methylation of the gene for vasoactive intestinal peptide in white-throated sparrows.
Mackenzie R Prichard, Kathleen E Grogan, Jennifer R Merritt, Jessica Root, Donna L Maney

Genes Brain Behav· November 2022

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Proximity-based labeling reveals DNA damage-induced phosphorylation of fused in sarcoma (FUS) causes distinct changes in the FUS protein interactome.
Michelle A Johnson, Thomas A Nuckols, Paola Merino, Pritha Bagchi, Srijita Nandy, Jessica Root

J Biol Chem· August 2022

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Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosis.
Jessica Root, Paola Merino, Austin Nuckols, Michelle Johnson, Thomas Kukar

Neurobiol Dis· July 2021

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Divergent FUS phosphorylation in primate and mouse cells following double-strand DNA damage.
Michelle A Johnson, Qiudong Deng, Georgia Taylor, Zachary T McEachin, Anthony W S Chan, Jessica Root

Neurobiol Dis· December 2020

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Human stuttering mutations engineered into mice cause vocalization deficits and astrocyte pathology in the corpus callosum.
Tae-Un Han, Jessica Root, Laura D Reyes, Elizabeth B Huchinson, Johann du Hoffmann

Proc Natl Acad Sci U S A· August 2019

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Association between Rare Variants in AP4E1, a Component of Intracellular Trafficking, and Persistent Stuttering.
M Hashim Raza, Rafael Mattera, Robert Morell, Eduardo Sainz, Rachel Rahn, Jessica Root

Am J Hum Genet· November 2015

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