Publications by authors named "Jessica Teh"

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Elevated NR2F1 underlies the persistence of invasive disease after treatment of BRAF-mutant melanoma.
Manoela Tiago, Timothy J Purwin, Casey D Stefanski, Renaira Oliveira da Silva, Mitchell E Fane, Jessica Lf Teh

J Clin Invest· September 2025

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Lineage commitment pathways epigenetically oppose oncogenic Gαq/11-YAP1 signaling in dormant disseminated uveal melanoma.
Rama Kadamb, Melisa Lopez Anton, Timothy J Purwin, Lornella Seeneevassen, Vivian Chua, Jessica L F Teh

bioRxiv· January 2025

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Oral Estrogen Receptor PROTAC Vepdegestrant (ARV-471) Is Highly Efficacious as Monotherapy and in Combination with CDK4/6 or PI3K/mTOR Pathway Inhibitors in Preclinical ER+ Breast Cancer Models.
Sheryl M Gough, John J Flanagan, Jessica Teh, Monica Andreoli, Emma Rousseau

Clin Cancer Res· August 2024

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BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition.
Marco H Hofmann, Michael Gmachl, Juergen Ramharter, Fabio Savarese, Daniel Gerlach, Jessica L Teh

Cancer Discov· January 2021

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Targeting PHGDH Upregulation Reduces Glutathione Levels and Resensitizes Resistant NRAS-Mutant Melanoma to MAPK Kinase Inhibition.
Mai Q Nguyen, Jessica L F Teh, Timothy J Purwin, Inna Chervoneva, Michael A Davies

J Invest Dermatol· November 2020

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Activation of CD8 T Cells Contributes to Antitumor Effects of CDK4/6 Inhibitors plus MEK Inhibitors.
Jessica L F Teh, Dan A Erkes, Phil F Cheng, Manoela Tiago, Nicole A Wilski

Cancer Immunol Res· September 2020

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Metabolic Adaptations to MEK and CDK4/6 Cotargeting in Uveal Melanoma.
Jessica L F Teh, Timothy J Purwin, Anna Han, Vivian Chua, Prem Patel

Mol Cancer Ther· August 2020

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Arrested Developments: CDK4/6 Inhibitor Resistance and Alterations in the Tumor Immune Microenvironment.
Jessica L F Teh, Andrew E Aplin

Clin Cancer Res· February 2019

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Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma.
Vivian Chua, Marlana Orloff, Jessica Lf Teh, Takahito Sugase, Connie Liao

EMBO Mol Med· February 2019

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Correction: E2F Reporting Reveals Efficacious Schedules of MEK1/2-CDK4/6 Targeting and mTOR-S6 Resistance Mechanisms.
Jessica L F Teh, Phil F Cheng, Timothy J Purwin, Neda Nikbakht, Prem Patel

Cancer Discov· December 2018

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Playing the Melanoma Endgame.
Jessica L F Teh, Andrew E Aplin

Clin Cancer Res· October 2018

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E2F Reporting Reveals Efficacious Schedules of MEK1/2-CDK4/6 Targeting and mTOR-S6 Resistance Mechanisms.
Jessica L F Teh, Phil F Cheng, Timothy J Purwin, Neda Nikbakht, Prem Patel

Cancer Discov· May 2018

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A Preexisting Rare Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in Melanoma and Is Dependent on S6K1 Signaling.
Gabriele Romano, Pei-Ling Chen, Ping Song, Jennifer L McQuade, Roger J Liang, Jessica L F Teh

Cancer Discov· May 2018

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Frizzled with age: an opportunity for 'gerontological medicine'.
Jessica L F Teh

Pigment Cell Melanoma Res· September 2016

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An In Vivo Reporter to Quantitatively and Temporally Analyze the Effects of CDK4/6 Inhibitor-Based Therapies in Melanoma.
Jessica L F Teh, Timothy J Purwin, Evan J Greenawalt, Inna Chervoneva, Allison Goldberg

Cancer Res· September 2016

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Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells.
Jessica L F Teh, Raj Shah, Stephanie La Cava, Sonia C Dolfi, Madhura S Mehta

Breast Cancer Res Treat· May 2015

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Metabotropic glutamate receptor 1 mediates melanocyte transformation via transactivation of insulin-like growth factor 1 receptor.
Jessica L F Teh, Raj Shah, Seung-Shick Shin, Yu Wen, Janice M Mehnert

Pigment Cell Melanoma Res· July 2014

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Metabotropic glutamate receptor 1 expression and its polymorphic variants associate with breast cancer phenotypes.
Madhura S Mehta, Sonia C Dolfi, Roman Bronfenbrener, Erhan Bilal, Chunxia Chen, Jessica Teh

PLoS One· April 2014

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Glutamatergic signaling in cellular transformation.
Jessica L F Teh, Suzie Chen

Pigment Cell Melanoma Res· May 2012

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mGlu Receptors and Cancerous Growth.
Jessica Teh, Suzie Chen

Wiley Interdiscip Rev Membr Transp Signal· March 2012

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