Publications by authors named "Jesuthas Ajendra"

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Escalation of Germinal Center Responses in Chronic Litomosoides sigmodontis Filarial Infection.
Teresa Steffen, Jesuthas Ajendra, Marianne Koschel, Alexander Palmen, Hannah Wegner

Eur J Immunol· May 2025

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Major basic protein and eosinophil peroxidase support microfilariae motility inhibition by eosinophil ETosis.
Pia Philippa Schumacher, Jesuthas Ajendra, Benjamin Lenz, Frederic Risch, Alexandra Ehrens

PLoS Negl Trop Dis· March 2025

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Eosinophils Are an Endogenous Source of Interleukin-4 during Filarial Infections and Contribute to the Development of an Optimal T Helper 2 Response.
Cécile Guth, Pia Philippa Schumacher, Archena Vijayakumar, Hannah Borgmann, Helene Balles, Jesuthas Ajendra

J Innate Immun· April 2024

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Repeated sensitization of mice with microfilariae of Litomosoides sigmodontis induces pulmonary eosinophilia in an IL-33-dependent manner.
Benjamin Lenz, Alexandra Ehrens, Jesuthas Ajendra, Frederic Risch, Joséphine Gal

PLoS Pathog· March 2024

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The IL-17A-neutrophil axis promotes epithelial cell IL-33 production during nematode lung migration.
Jesuthas Ajendra, Pedro H Papotto, James E Parkinson, Rebecca J Dodd, André L Bombeiro

Mucosal Immunol· December 2023

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T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity.
Conor M Finlay, James E Parkinson, Lili Zhang, Brian H K Chan, Jesuthas Ajendra

Immunity· May 2023

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Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode .
Johanna F Scheunemann, Frederic Risch, Julia J Reichwald, Benjamin Lenz, Anna-Lena Neumann, Jesuthas Ajendra

Vaccines (Basel)· May 2023

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Neutrophils: Friend or foe in Filariasis?
Jesuthas Ajendra, Judith E Allen

Parasite Immunol· June 2022

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IL-13 deficiency exacerbates lung damage and impairs epithelial-derived type 2 molecules during nematode infection.
Alistair L Chenery, Silvia Rosini, James E Parkinson, Jesuthas Ajendra, Jeremy A Herrera

Life Sci Alliance· August 2021

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Lessons in type 2 immunity: Neutrophils in Helminth infections.
Jesuthas Ajendra

Semin Immunol· March 2021

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IL-17A both initiates, via IFNγ suppression, and limits the pulmonary type-2 immune response to nematode infection.
Jesuthas Ajendra, Alistair L Chenery, James E Parkinson, Brian H K Chan, Stella Pearson

Mucosal Immunol· November 2020

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Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung.
Alistair L Chenery, Rafid Alhallaf, Zainab Agha, Jesuthas Ajendra, James E Parkinson

J Immunol· November 2019

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TGFβ depletion does neither modulate acute E. coli-induced inflammatory immune responses nor impair the protective effect by chronic filarial infection.
Benedikt C Buerfent, Jesuthas Ajendra, Wiebke Stamminger, Fabian Gondorf, Achim Hoerauf

GMS Infect Dis· November 2019

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Susceptibility to L. sigmodontis infection is highest in animals lacking IL-4R/IL-5 compared to single knockouts of IL-4R, IL-5 or eosinophils.
Stefan J Frohberger, Jesuthas Ajendra, Jayagopi Surendar, Wiebke Stamminger, Alexandra Ehrens

Parasit Vectors· May 2019

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IL-6 is required for protective immune responses against early filarial infection.
Muhsin Muhsin, Jesuthas Ajendra, Katrin Gentil, Afiat Berbudi, Anna-Lena Neumann

Int J Parasitol· October 2018

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Filarial Infection or Antigen Administration Improves Glucose Tolerance in Diet-Induced Obese Mice.
Afiat Berbudi, Jayagopi Surendar, Jesuthas Ajendra, Fabian Gondorf, David Schmidt

J Innate Immun· October 2017

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NOD2 dependent neutrophil recruitment is required for early protective immune responses against infectious Litomosoides sigmodontis L3 larvae.
Jesuthas Ajendra, Sabine Specht, Sebastian Ziewer, Andrea Schiefer, Kenneth Pfarr

Sci Rep· December 2016

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Parasitic helminths and their beneficial impact on type 1 and type 2 diabetes.
Afiat Berbudi, Jesuthas Ajendra, Ajeng P F Wardani, Achim Hoerauf, Marc P Hübner

Diabetes Metab Res Rev· March 2016

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Combination of worm antigen and proinsulin prevents type 1 diabetes in NOD mice after the onset of insulitis.
Jesuthas Ajendra, Afiat Berbudi, Achim Hoerauf, Marc P Hübner

Clin Immunol· March 2016

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Development of patent Litomosoides sigmodontis infections in semi-susceptible C57BL/6 mice in the absence of adaptive immune responses.
Laura E Layland, Jesuthas Ajendra, Manuel Ritter, Anna Wiszniewsky, Achim Hoerauf

Parasit Vectors· July 2015

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Chronic filarial infection provides protection against bacterial sepsis by functionally reprogramming macrophages.
Fabian Gondorf, Afiat Berbudi, Benedikt C Buerfent, Jesuthas Ajendra, Dominique Bloemker

PLoS Pathog· January 2015

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ST2 deficiency does not impair type 2 immune responses during chronic filarial infection but leads to an increased microfilaremia due to an impaired splenic microfilarial clearance.
Jesuthas Ajendra, Sabine Specht, Anna-Lena Neumann, Fabian Gondorf, David Schmidt

PLoS One· November 2014

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