Publications by authors named "Jiakang Sun"

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Multi-target renal protection in AKI: Exercise-mediated coordination of AMPK energy homeostasis, mTOR autophagy regulation, and NF-κB inflammatory control.
Xishuai Wang, Zhixin Li, Cong Liu, Kangli Du, Lijia Hou, Jiakang Sun, Xiaodi Sun, Shengkun Sun

Free Radic Biol Med· December 2025

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SHR-A1811, a novel anti-HER2 antibody-drug conjugate with optimal drug-to-antibody ratio, efficient tumor killing potency, and favorable safety profiles.
Ting Zhang, Jianyan Xu, Junzhao Yin, Yun Gao, Hanwen Zheng, Jiakang Sun, Xing Sun

PLoS One· June 2025

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Phased therapeutic intervention improves long-term prognosis of new hemodialysis patients.
Jiakang Sun, Fei Guo, Deheng Wan, Yan Wang

Pak J Med Sci· December 2024

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Effect of periodic nursing interventions on improving compliance behavior and health status in long-term Hemodialysis patients.
Yan Wang, Jiakang Sun, Fei Guo, Deheng Wan

Pak J Med Sci· October 2024

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Medical image analysis using improved SAM-Med2D: segmentation and classification perspectives.
Jiakang Sun, Ke Chen, Zhiyi He, Siyuan Ren, Xinyang He

BMC Med Imaging· September 2024

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Discovery of spiro amide SHR902275: A potent, selective, and efficacious RAF inhibitor targeting RAS mutant cancers.
Peng Zhao, Linghang Zhuang, Xiangzhu Wang, Song Huang, Heping Wu, Jiakang Sun

Eur J Med Chem· January 2022

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Discovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis.
Suxing Liu, Dong Liu, Ru Shen, Di Li, Qiyue Hu, Jiakang Sun

Sci Rep· April 2021

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Discovery of SHR1653, a Highly Potent and Selective OTR Antagonist with Improved Blood-Brain Barrier Penetration.
Xin Li, Zhigao Zhang, Yang Chen, Hong Wan, Jiakang Sun

ACS Med Chem Lett· June 2019

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A Secure and High-Fidelity Live Animal Model for Off-Pump Coronary Bypass Surgery Training.
Xiaopeng Liu, Yan Yang, Qiang Meng, Jiakang Sun, Fuliang Luo

J Surg Educ· March 2017

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Transapical implantation of a self-expandable aortic valve prosthesis utilizing a novel designed positioning element.
Xiaopeng Liu, Yue Tang, Fuliang Luo, Yi Tian, Kai Li, Jiakang Sun

Catheter Cardiovasc Interv· January 2017

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Optimized protein kinase Cθ (PKCθ) inhibitors reveal only modest anti-inflammatory efficacy in a rodent model of arthritis.
Dawn M George, Eric C Breinlinger, Maria A Argiriadi, Yang Zhang, Jianfei Wang, Jiakang Sun

J Med Chem· January 2015

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LCK: a new biomarker candidate for the early diagnosis of acute myocardial infarction.
Fei Xu, Xiao Teng, Xin Yuan, Jiakang Sun, Hengchao Wu

Mol Biol Rep· December 2014

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Neural progenitor cells derived from adult bone marrow mesenchymal stem cells promote neuronal regeneration.
Yue Tang, Yong-Chun Cui, Xiao-Juan Wang, Ai-Li Wu, Guang-Fu Hu, Jia-Kang Sun, Jing Sun

Life Sci· November 2012

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The yeast mitochondrial citrate transport protein: molecular determinants of its substrate specificity.
Sreevidya Aluvila, Rusudan Kotaria, Jiakang Sun, June A Mayor, D Eric Walters

J Biol Chem· August 2010

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Probing the effect of transport inhibitors on the conformation of the mitochondrial citrate transport protein via a site-directed spin labeling approach.
June A Mayor, Jiakang Sun, Rusudan Kotaria, D Eric Walters, Kyoung Joon Oh

J Bioenerg Biomembr· April 2010

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Inhibitors of the mitochondrial citrate transport protein: validation of the role of substrate binding residues and discovery of the first purely competitive inhibitor.
Sreevidya Aluvila, Jiakang Sun, David H T Harrison, D Eric Walters, Ronald S Kaplan

Mol Pharmacol· January 2010

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Mitochondrial and Plasma Membrane Citrate Transporters: Discovery of Selective Inhibitors and Application to Structure/Function Analysis.
Jiakang Sun, Sreevidya Aluvila, Rusudan Kotaria, June A Mayor, D Eric Walters

Mol Cell Pharmacol· January 2010

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The yeast mitochondrial citrate transport protein: identification of the Lysine residues responsible for inhibition mediated by Pyridoxal 5'-phosphate.
Sreevidya Remani, Jiakang Sun, Rusudan Kotaria, June A Mayor, June M Brownlee

J Bioenerg Biomembr· December 2008

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Identification of the substrate binding sites within the yeast mitochondrial citrate transport protein.
Chunlong Ma, Sreevidya Remani, Jiakang Sun, Rusudan Kotaria, June A Mayor

J Biol Chem· June 2007

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