Publications by authors named "Jiang-Ping Xu"

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Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats.
Bing-Tian Xu, Meng-Fan Li, Ke-Chun Chen, Xing Li, Ning-Bo Cai, Jiang-Ping Xu

Acta Pharmacol Sin· March 2023

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Advances in the development of phosphodiesterase 7 inhibitors.
Jia-Xi Huang, Bo-Lin Zhu, Jiang-Ping Xu, Zhong-Zhen Zhou

Eur J Med Chem· March 2023

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Discovery of novel 2,3-dihydro-1H-inden-1-ones as dual PDE4/AChE inhibitors with more potency against neuroinflammation for the treatment of Alzheimer's disease.
Jie Liu, Lu Liu, Lei Zheng, Kai-Wen Feng, Hai-Tao Wang, Jiang-Ping Xu

Eur J Med Chem· August 2022

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Discovery of Novel 3-Amino-4-alkoxyphenylketones as PDE4 Inhibitors with Improved Oral Bioavailability and Safety against Spatial Memory Impairments.
Chuang Xia, Jia-Peng He, Kai-Wen Feng, Lu Liu, Lei Zheng, Jiang-Ping Xu

ACS Chem Neurosci· February 2022

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Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson's disease models.
Wen-Li Dong, Jia-Hong Zhong, Yun-Qing Chen, Jin-Feng Xie, Yun-Yun Qin, Jiang-Ping Xu

Acta Pharmacol Sin· December 2021

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Discovery of novel trimethoxyphenylbenzo[d]oxazoles as dual tubulin/PDE4 inhibitors capable of inducing apoptosis at G2/M phase arrest in glioma and lung cancer cells.
Jie Liu, Wan Ye, Jiang-Ping Xu, Hai-Tao Wang, Xiao-Fang Li

Eur J Med Chem· November 2021

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AMI, an Indazole Derivative, Improves Parkinson's Disease by Inhibiting Tau Phosphorylation.
Zhang Mao, Zhu Wen-Ting, Wang Hai-Tao, Yu Hui, Lan Shi-Yi, Xu Jiang-Ping

Front Mol Neurosci· November 2020

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Copper Regulates the Susceptibility of Zebrafish Larvae to Inflammatory Stimuli by Controlling Neutrophil/Macrophage Survival.
MingYue Chen, Yi Luo, JiangPing Xu, Ming-Xian Chang, Jing-Xia Liu

Front Immunol· October 2020

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Acute EPA-induced learning and memory impairment in mice is prevented by DHA.
Ji-Hong Liu, Qian Wang, Qiang-Long You, Ze-Lin Li, Neng-Yuan Hu, Jiang-Ping Xu

Nat Commun· October 2020

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Synthesis, Biological Evaluation, and Molecular Docking of Arylpyridines as Antiproliferative Agent Targeting Tubulin.
JiaPeng He, Mao Zhang, Lv Tang, Jie Liu, JiaHong Zhong, Jiang-Ping Xu

ACS Med Chem Lett· August 2020

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Reciprocal Substitution Between Methamphetamine and Heroin in Terms of Reinforcement Effects in Rats.
Di-Sen Mei, Yu-Jia Cai, Fang-Min Wang, Bao-Miao Ma, Hui-Fen Liu, Jiang-Ping Xu

Front Psychiatry· July 2020

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Protective effect of gui zhi (Ramulus Cinnamomi) on abnormal levels of four amino acid neurotransmitters by chronically ma huang (Herb Ephedra) intoxicated prefrontal cortex in rats treated with a ma huang-gui zhi herb pair.
Bo Niu, Fang-Hao Zheng, Jiang-Ping Xu

J Ethnopharmacol· March 2020

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A new polyhydroxylated oleanane triterpenoid from the roots of .
Xue-Li Tong, Hai-Tao Wang, Jiang-Ping Xu, Li-Wen Tian

Nat Prod Res· January 2020

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Chronic unpredictable mild stress induced depression-like behaviours and glutamate-glutamine cycling dysfunctions in both blood and brain of mice.
Ya-Ping Chen, Chuang Wang, Jiang-Ping Xu

Pharm Biol· December 2019

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Discovery of 2-(3,4-dialkoxyphenyl)-2-(substituted pyridazin-3-yl)acetonitriles as phosphodiesterase 4 inhibitors with anti-neuroinflammation potential based on three-dimensional quantitative structure-activity relationship study.
Chang Huang, Qiu-Ping Zhong, Lv Tang, Hai-Tao Wang, Jiang-Ping Xu

Chem Biol Drug Des· April 2019

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Discovery of arylbenzylamines as PDE4 inhibitors with potential neuroprotective effect.
Lv Tang, Chang Huang, Jiahong Zhong, JiaPeng He, Jiayin Guo, Jiang-Ping Xu

Eur J Med Chem· April 2019

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Correction to Discovery of N-Alkyl Catecholamides as Selective Phosphodiesterase-4 Inhibitors with Anti-neuroinflammation Potential Exhibiting Antidepressant-like Effects at Non-emetic Doses.
Zhong-Zhen Zhou, Yu-Fang Cheng, Zheng-Qiang Zou, Bing-Chen Ge, Hui Yu, Xue-Mei Yang, Jiang-Ping Xu

ACS Chem Neurosci· July 2018

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Design, synthesis and biological evaluation of substituted aminopyridazin-3(2H)-ones as G0/G1-phase arresting agents with apoptosis-inducing activities.
Bing-Chen Ge, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Bao-Ming Xi, Xue-Mei Yang, Jiang-Ping Xu

Eur J Med Chem· December 2017

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Copper impairs zebrafish swimbladder development by down-regulating Wnt signaling.
JiangPing Xu, RuiTao Zhang, Ting Zhang, Guang Zhao, Yan Huang

Aquat Toxicol· November 2017

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Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents.
Mei-Fang Gong, Rui-Ting Wen, Ying Xu, Jian-Chun Pan, Ning Fei, Jiang-Ping Xu

Psychopharmacology (Berl)· October 2017

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Discovery of 9H-purins as potential tubulin polymerization inhibitors: Synthesis, biological evaluation and structure-activity relationships.
Zhong-Zhen Zhou, Xiu-Dong Shi, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Jiang-Ping Xu

Eur J Med Chem· September 2017

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Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-B Inhibition.
Zheng-Qiang Zou, Jia-Jia Chen, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Jiang-Ping Xu

J Pharmacol Exp Ther· July 2017

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Discovery of N-Alkyl Catecholamides as Selective Phosphodiesterase-4 Inhibitors with Anti-neuroinflammation Potential Exhibiting Antidepressant-like Effects at Non-emetic Doses.
Zhong-Zhen Zhou, Yu-Fang Cheng, Zheng-Qiang Zou, Bing-Chen Ge, Hui Yu, Xue-Mei Yang, Jiang-Ping Xu

ACS Chem Neurosci· January 2017

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[Role of cAMP/CREB/BDNF signaling pathway in anti-depressive effect of vortioxetine in mice].
Hui Yu, Jia-Jia Chen, Bing-Qing Zeng, Qiu-Ping Zhong, Jiang-Ping Xu

Nan Fang Yi Ke Da Xue Xue Bao· January 2017

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Development of highly potent phosphodiesterase 4 inhibitors with anti-neuroinflammation potential: Design, synthesis, and structure-activity relationship study of catecholamides bearing aromatic rings.
Zhong-Zhen Zhou, Bing-Chen Ge, Qiu-Ping Zhong, Chang Huang, Yu-Fang Cheng, Xue-Mei Yang, Jiang-Ping Xu

Eur J Med Chem· November 2016

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