Publications by authors named "Jianlan Gu"

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Synaptic scaffold protein PSD-95: a therapeutic target for Alzheimer's disease.
Xing Fan, Hao Wang, Jianchao Ping, Mingzhe Li, Jianlan Gu

Biochem Pharmacol· December 2025

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Ganglioside sialylation modulates tau internalization and pathology spread.
Shiying Li, Yuanyuan Chen, Tianling Song, Dong Liu, Ruozhen Wu, Jianlan Gu, Jin-Hua Gu

Mol Psychiatry· December 2025

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Dimer-Specific FokT-seq Reveals DNA-Binding Dimerization and Novel Genomic Targets of TDP-43.
Mingming Yang, Qi Wang, Ruolan Yan, Xiaochuan Wang, Jianlan Gu

Adv Sci (Weinh)· November 2025

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Neuroprotective mechanism of LincRNA in neurodegenerative diseases.
Yizhou Lin, Jiarui Wang, Bowen Liu, Tianye Hu, Jianlan Gu

Gene· October 2025

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Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP-43-Associated ALS and AD.
Mingming Yang, Qi Wang, Dongkun Kang, Shijia Wang, Yanli Jiang, Jianlan Gu

Adv Sci (Weinh)· September 2025

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Rhythmic TDP-43 affects RNA splicing of USP13, resulting in alteration of BMAL1 ubiquitination.
Jianlan Gu, Mingming Yang, Liti Zhang, Yuxiao Liu, Ruolan Yan

J Cell Biol· May 2025

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LINC00894 inhibited neuron cellular apoptosis and regulated activating transcription factor 3 expression.
Hanjing Hu, Yuxiao Liu, Cheng Qiu, Liti Zhang, Hengxiang Cui, Jianlan Gu

Gene· November 2024

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Two simple assays for assessing the seeding activity of proteopathic tau.
Fei Liu, Ruozhen Wu, Nana Jin, Dandan Chu, Jianlan Gu

Front Aging Neurosci· April 2023

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Casein Kinase 1δ Phosphorylates TDP-43 and Suppresses Its Function in Tau mRNA Processing.
Mingming Yang, Rongrong Qi, Yuxiao Liu, Xin Shen, Yulou Zhao, Jianlan Gu

J Alzheimers Dis· March 2023

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Tau seeding activity in various regions of down syndrome brain assessed by two novel assays.
Nana Jin, Jianlan Gu, Ruozhen Wu, Dandan Chu, Yunn Chyn Tung

Acta Neuropathol Commun· September 2022

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Excess folic acid supplementation before and during pregnancy and lactation activates β-catenin in the brain of male mouse offspring.
Qian Wu, Dingwei Zhou, Ruozhen Wu, Ruirui Shi, Xin Shen, Jianlan Gu, Jin-Hua Gu

Brain Res Bull· January 2022

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Seeding-Competent Tau in Gray Matter Versus White Matter of Alzheimer's Disease Brain.
Ruozhen Wu, Jianlan Gu, Dingwei Zhou, Yunn Chyn Tung, Nana Jin

J Alzheimers Dis· September 2021

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Phosphorylation of trans-active response DNA-binding protein-of 43 kDa promotes its cytoplasmic aggregation and modulates its function in tau mRNA stability and exon 10 alternative splicing.
Ruozhen Wu, Dingwei Zhou, Xin Shen, Feng Chen, Fei Liu, Jianlan Gu

J Neurochem· August 2021

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Dephosphorylation Passivates the Seeding Activity of Oligomeric Tau Derived From Alzheimer's Brain.
Ruozhen Wu, Longfei Li, Ruirui Shi, Yan Zhou, Nana Jin, Jianlan Gu

Front Mol Neurosci· May 2021

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High Mobility Group Box 1 Ameliorates Cognitive Impairment in the 3×Tg-AD Mouse Model.
Jin Zhang, Xue-Feng Hua, Jinhua Gu, Feng Chen, Jianlan Gu

J Alzheimers Dis· April 2021

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Alzheimer's disease brain contains tau fractions with differential prion-like activities.
Longfei Li, Ruirui Shi, Jianlan Gu, Yunn Chyn Tung, Yan Zhou

Acta Neuropathol Commun· February 2021

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Tau in Alzheimer's Disease: Pathological Alterations and an Attractive Therapeutic Target.
Jian-Lan Gu, Fei Liu

Curr Med Sci· December 2020

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Cyclic AMP-Dependent Protein Kinase Phosphorylates TDP-43 and Modulates Its Function in Tau mRNA Processing.
Jianlan Gu, Dandan Chu, Nana Jin, Feng Chen, Fei Liu

J Alzheimers Dis· October 2020

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Truncation of Tau selectively facilitates its pathological activities.
Jianlan Gu, Wen Xu, Nana Jin, Longfei Li, Yan Zhou

J Biol Chem· October 2020

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Elevation of casein kinase 1ε associated with TDP-43 and tau pathologies in Alzheimer's disease.
Jianlan Gu, Wen Hu, Xuefeng Tan, Shuting Qu, Dandan Chu

Brain Pathol· March 2020

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Rbfox3/NeuN Regulates Alternative Splicing of Tau Exon 10.
Jianlan Gu, Feng Chen, Dandan Chu, Ying Lu, Khalid Iqbal

J Alzheimers Dis· November 2019

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Calpain I Activation Causes GLUT3 Proteolysis and Downregulation of O-GlcNAcylation in Alzheimer's Disease Brain.
Jianlan Gu, Nana Jin, Denglei Ma, Dandan Chu, Khalid Iqbal

J Alzheimers Dis· May 2019

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Sirt1 enhances tau exon 10 inclusion and improves spatial memory of Htau mice.
Shuo Qian, Jianlan Gu, Wufei Dai, Nana Jin, Dandan Chu

Aging (Albany NY)· September 2018

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Protein Phosphatase 1 dephosphorylates TDP-43 and suppresses its function in tau exon 10 inclusion.
Jianlan Gu, Weihua Wang, Shichen Miao, Feng Chen, Feng Wu

FEBS Lett· February 2018

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O-GlcNAcylation modulates PKA-CREB signaling in a manner specific to PKA catalytic subunit isoforms.
Nana Jin, Denglei Ma, Jianlan Gu, Jianhua Shi, Xiaotao Xu

Biochem Biophys Res Commun· February 2018

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