Publications by authors named "Jianwei Che"

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Small-molecule allosteric activator of ubiquitin-specific protease 7 (USP7).
Isabella Jaen Maisonet, Mona Sharafi, Emilie J Korchak, Andres Salazar-Chaparro, Ariana S Bratt, Jianwei Che

Proc Natl Acad Sci U S A· October 2025

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Atomic-Scale Interface Engineering via Ultrasonic-Electrochemical Hybrid Polishing: Achieving Damage-Free NiTi Bipolar Plates with Ultra-Low Contact Resistance for Hydrogen Fuel Cells.
Jianwei Che, Xinyue Zhang, Hui Li, Guangfeng Shi

Langmuir· September 2025

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Expanding the druggable zinc-finger proteome defines properties of drug-induced degradation.
Mikołaj Słabicki, Jiho Park, Radosław P Nowak, Shourya S Roy Burman, Jesse Pellman, Jianwei Che, Chelsea Shu, Eric S Fischer

Mol Cell· August 2025

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Plasmodiumfalciparum protein kinase 6 and hemozoin formation are inhibited by a type II human kinase inhibitor exhibiting antimalarial activity.
Flore Nardella, Tiantian Jiang, Lushun Wang, Monica J Bohmer, Subhoja Chakraborty, Jianwei Che, Daisy Chen

Cell Chem Biol· July 2025

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Unveiling the hidden interactome of CRBN molecular glues.
Kheewoong Baek, Rebecca J Metivier, Shourya S Roy Burman, Jonathan W Bushman, Hojong Yoon, Jianwei Che, Eric S Fischer

Nat Commun· July 2025

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Antitumor Activity of Vebreltinib and Characterization of Clinicogenomic Features in Solid Tumors with MET Rearrangements.
Seshiru Nakazawa, Federica Pecci, Igor Odintsov, Dimitris Gazgalis, Felix H Gottlieb, Pan Chen, Jianwei Che

Cancer Discov· June 2025

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Structure-guided design of a truncated heterobivalent chemical probe degrader of IRE1α.
Breanna L Zerfas, Yingpeng Liu, Jianwei Che, Katherine A Donovan, John M Hatcher, Eric S Fischer

RSC Med Chem· March 2025

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Small-molecule allosteric activator of ubiquitin-specific protease 7 (USP7).
Isabella Jaen Maisonet, Mona Sharafi, Emilie J Korchak, Andres Salazar-Chaparro, Ariana Bratt, Jianwei Che

bioRxiv· March 2025

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The human zinc-binding cysteine proteome.
Nils Burger, Melanie J Mittenbühler, Haopeng Xiao, Sanghee Shin, Shelley M Wei, Jianwei Che

Cell· February 2025

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Discovery of Potent Degraders of the Dengue Virus Envelope Protein.
Zhengnian Li, Han-Yuan Liu, Zhixiang He, Antara Chakravarty, Ryan P Golden, Jianwei Che, Isaac Che, Eric S Fischer

Adv Sci (Weinh)· October 2024

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Activating Point Mutations in the MET Kinase Domain Represent a Unique Molecular Subset of Lung Cancer and Other Malignancies Targetable with MET Inhibitors.
Federica Pecci, Seshiru Nakazawa, Biagio Ricciuti, Guilherme Harada, Jessica K Lee, Adriana Barrichello, Monica F Chen, Jianwei Che

Cancer Discov· August 2024

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Discovery of Potent Degraders of the Dengue Virus Envelope Protein.
Zhengnian Li, Han-Yuan Liu, Zhixiang He, Antara Chakravarty, Ryan P Golden, Jianwei Che, Isaac Che, Eric S Fischer

bioRxiv· June 2024

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Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality.
Zhengnian Li, Jie Jiang, Scott B Ficarro, Tyler S Beyett, Ciric To, Jianwei Che

ACS Cent Sci· June 2024

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ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases.
Zhengnian Li, Wenchao Lu, Tyler S Beyett, Scott B Ficarro, Jie Jiang, Jianwei Che

J Med Chem· February 2024

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Development of sulfonyl fluoride chemical probes to advance the discovery of cereblon modulators.
Yingpeng Liu, Radosław P Nowak, Jianwei Che, Katherine A Donovan, Fidel Huerta, Eric S Fischer

RSC Med Chem· February 2024

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A comprehensive landscape of the zinc-regulated human proteome.
Nils Burger, Melanie J Mittenbühler, Haopeng Xiao, Sanghee Shin, Luiz H M Bozi, Jianwei Che

bioRxiv· January 2024

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Development and Characterization of Selective FAK Inhibitors and PROTACs with In Vivo Activity.
Eriko Koide, Mikaela L Mohardt, Zainab M Doctor, Annan Yang, Mingfeng Hao, Jianwei Che, Eric S Fischer

Chembiochem· October 2023

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Proteomics-Based Discovery of First-in-Class Chemical Probes for Programmed Cell Death Protein 2 (PDCD2).
Wenzhi Ji, Woong Sub Byun, Wenchao Lu, Xijun Zhu, Katherine A Donovan, Jianwei Che, Eric S Fischer

Angew Chem Int Ed Engl· October 2023

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Lactate regulates cell cycle by remodelling the anaphase promoting complex.
Weihai Liu, Yun Wang, Luiz H M Bozi, Patrick D Fischer, Mark P Jedrychowski, Jianwei Che

Nature· April 2023

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Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors.
Wenchao Lu, Mengyang Fan, Wenzhi Ji, Jason Tse, Inchul You, Jianwei Che

J Med Chem· April 2023

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HiBiT-SpyTag: A Minimal Tag for Covalent Protein Capture and Degrader Development.
Tiffany Tsang, Fidel Huerta, Yingpeng Liu, Jianwei Che, Rebecca J Metivier

ACS Chem Biol· April 2023

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Catalytic Degraders Effectively Address Kinase Site Mutations in EML4-ALK Oncogenic Fusions.
Yang Gao, Baishan Jiang, Hellen Kim, Matthew J Berberich, Jianwei Che, John M Hatcher, Eric S Fischer

J Med Chem· April 2023

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Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1.
Wenchao Lu, Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Jianwei Che

J Med Chem· March 2023

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Structural rationalization of GSPT1 and IKZF1 degradation by thalidomide molecular glue derivatives.
Radosław P Nowak, Jianwei Che, Silas Ferrao, Nikki R Kong, Hu Liu

RSC Med Chem· March 2023

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