Publications by authors named "Jignesh Nagar"

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Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology.
Yam B Poudel, Liqi He, Matthew Cox, Qian Zhang, Walter L Johnson, Jignesh Nagar

ACS Med Chem Lett· February 2024

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Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology.
Liqi He, Meng Yao Zhang, Matthew Cox, Qian Zhang, Andrew F Donnell, Jignesh Nagar

ACS Med Chem Lett· February 2024

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Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction.
Ricardo A García, John A Lupisella, Bruce R Ito, Mei-Yin Hsu, Gayani Fernando, Jignesh Nagar

JACC Basic Transl Sci· August 2021

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Azatricyclic Inverse Agonists of RORγt That Demonstrate Efficacy in Models of Rheumatoid Arthritis and Psoriasis.
Qingjie Liu, Hai-Yun Xiao, Douglas G Batt, Zili Xiao, Yeheng Zhu, Jignesh Nagar

ACS Med Chem Lett· May 2021

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Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis.
Satheesh Nair, Sreekantha Ratna Kumar, Venkatram Reddy Paidi, Ramesh Sistla, Durgarao Kantheti, Jignesh Nagar

ACS Med Chem Lett· July 2020

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Diminished responses to monoaminergic antidepressants but not ketamine in a mouse model for neuropsychiatric lupus.
Bettadapura N Srikumar, Pattipati S Naidu, Narasimharaju Kalidindi, Mahesh Paschapur, Bharath Adepu, Jignesh Nagar

J Psychopharmacol· January 2019

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Bruton's tyrosine kinase inhibitor BMS-986142 in experimental models of rheumatoid arthritis enhances efficacy of agents representing clinical standard-of-care.
Kathleen M Gillooly, Claudine Pulicicchio, Mark A Pattoli, Lihong Cheng, Stacey Skala, Jignesh Nagar

PLoS One· September 2017

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Effect of pioglitazone on metabolic features in endotoxemia model in obese diabetic db/db mice.
Manoranjan Sharma, Jogeswar Mohapatra, Umar Malik, Jignesh Nagar, Abhijit Chatterjee

J Diabetes· June 2017

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Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity.
Shailesh Dudhgaonkar, Sourabh Ranade, Jignesh Nagar, Siva Subramani, Durga Shiv Prasad

J Immunol· February 2017

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Differential effects of dexamethasone and rosiglitazone in a sephadex-induced model of lung inflammation in rats: possible role of tissue inhibitor of metalloproteinase-3.
Jignesh K Nagar, Praful P Patel, Jogeswar N Mohapatra, Manoranjan M Sharma, Gaurav M Pandya

Indian J Pharmacol· January 2016

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Therapeutic potential of chloroquine in a murine model of inflammatory bowel disease.
Jignesh Nagar, Sourabh Ranade, Vinay Kamath, Sharad Singh, Preethi Karunanithi

Int Immunopharmacol· August 2014

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