Publications by authors named "Jignesh Prajapati"

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Quercetin as a selective quorum sensing inhibitor: in silico and in vitro analyses against Pseudomonas syringae with limited impact on plant growth-promoting bacteria.
Shivangi Bhatt, Jignesh Prajapati, Dweipayan Goswami, Meenu Saraf

Mol Divers· October 2025

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Decoding the structure of isopentenyl Diphosphate Delta-Isomerase protein from Vahl.
Khushali Thaker, Jaimini Patoliya, Jignesh Prajapati, Khushbu Rabadiya, Manivel Ponnuchamy

J Biomol Struct Dyn· September 2025

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Sennoside A from Cassia angustifolia as a mixed-type inhibitor of DPP-IV: Integrative in vitro, in silico, and kinetic characterization.
Srishti Chhabria, Shivangi Mathur, Sebastian Vadakan, Dweipayan Goswami, Jignesh Prajapati

Biochem Biophys Res Commun· September 2025

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Development of coumarin-inspired bifunctional hybrids as a new class of anti-Alzheimer's agents with potent efficacy.
Atamjit Singh, Aman Sharma, Karanvir Singh, Kirandeep Kaur, Pallvi Mohana, Jignesh Prajapati

RSC Med Chem· May 2025

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Biochanin A, an isoflavone isolated from Roxb. ex DC., leaves promote ROS-mediated and caspase-dependent apoptosis in lung adenocarcinoma cells.
Anjali B Thakkar, Ramalingam B Subramanian, Vasudev R Thakkar, Sampark S Thakkar, Jignesh Prajapati

J Biomol Struct Dyn· May 2025

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Prenatal opioid exposure alters pain perception and increases long-term health risks in infants with neonatal opioid withdrawal syndrome.
Uppala Radhakrishna, Rupa Radhakrishnan, Lavanya V Uppala, Tithi S Trivedi, Jignesh Prajapati

Front Pain Res (Lausanne)· April 2025

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Hepatoprotective effects of phytochemicals and plant extracts against chemotherapy-induced liver damage in animal models: a systematic review.
Jignesh Prajapati, Narendra Bhatt, Rakesh Rawal

Arch Toxicol· March 2025

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MurG as a potential target of quercetin in Staphylococcus aureus supported by evidence from subtractive proteomics and molecular dynamics.
Dweipayan Goswami, Jignesh Prajapati, Milan Dabhi, Liam K R Sharkey, Sacha J Pidot

Sci Rep· March 2025

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Cytotoxic and immunomodulatory properties of Tinospora cordifolia, Boerhaavia diffusa, Berberis aristata, and Ocimum basilicum extracts against HPV-positive cervical cancer cell line.
Harsha Vaghasia, Rahul Patel, Jignesh Prajapati, Krupa Shah, Meenu Saraf

BMC Complement Med Ther· February 2025

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Impaired Molecular Mechanisms Contributing to Chronic Pain in Patients with Hidradenitis Suppurativa: Exploring Potential Biomarkers and Therapeutic Targets.
Uppala Radhakrishna, Murali R Kuracha, Iltefat Hamzavi, Nazia Saiyed, Jignesh Prajapati

Int J Mol Sci· January 2025

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Integrative bioinformatics and drug repurposing for metastatic prostate cancer: identifying novel therapeutic targets by transcriptional profiling and molecular Modeling.
Haseeb Nisar, Jignesh Prajapati, Asma Muhammad Mumtaz, Atiqa Iftikhar, Faria Faran

Integr Biol (Camb)· January 2025

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Comprehensive computational investigation for ligand recognition and binding dynamics of SdiA: a degenerate LuxR -type receptor in Klebsiella pneumoniae.
Janki Panchal, Jignesh Prajapati, Milan Dabhi, Arun Patel, Sandip Patel

Mol Divers· December 2024

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Antimicrobial Resistance Surveillance in Human Pathogens in Ahmedabad: A One-Year Prospective Study.
Milan Dabhi, Jignesh Prajapati, Janki Panchal, Bhavin Kapadiya, Meenu Saraf

Indian J Microbiol· December 2024

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Integrative bioinformatic analysis to identify potential phytochemical candidates for glioblastoma.
Hafiza Maria Usmani Rana, Haseeb Nisar, Jignesh Prajapati, Dweipayan Goswami, Ravi Rawat

Heliyon· December 2024

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Sexual dimorphism in neurobehavioural phenotype and gut microbial composition upon long-term exposure to structural analogues of bisphenol-A.
Dhirendra Pratap Singh, Aasish Kumar, Jignesh Prajapati, Vandana Bijalwan, Jitesh Kumar

J Hazard Mater· September 2024

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Multidisciplinary advances in kombucha fermentation, health efficacy, and market evolution.
Karan Prajapati, Jignesh Prajapati, Dhaval Patel, Rohit Patel, Anish Varshnei

Arch Microbiol· August 2024

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Prenatal opioid exposure significantly impacts placental protein kinase C (PKC) and drug transporters, leading to drug resistance and neonatal opioid withdrawal syndrome.
Uppala Radhakrishna, Rupa Radhakrishnan, Lavanya V Uppala, Srinivas B Muvvala, Jignesh Prajapati

Front Neurosci· August 2024

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Discovery of triazole tethered thymol/carvacrol-coumarin hybrids as new class of α-glucosidase inhibitors with potent in vivo antihyperglycemic activities.
Atamjit Singh, Karanvir Singh, Kirandeep Kaur, Aman Sharma, Pallvi Mohana, Jignesh Prajapati

Eur J Med Chem· January 2024

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Pinpointing top inhibitors for GSK3β from pool of indirubin derivatives using rigorous computational workflow and their validation using molecular dynamics (MD) simulations.
Vamangi Pandya, Priyashi Rao, Jignesh Prajapati, Rakesh M Rawal, Dweipayan Goswami

Sci Rep· January 2024

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The development of thymol-isatin hybrids as broad-spectrum antibacterial agents with potent anti-MRSA activity.
Atamjit Singh, Kirandeep Kaur, Pallvi Mohana, Karanvir Singh, Aman Sharma, Jignesh Prajapati

RSC Med Chem· January 2024

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Potential dual inhibition of SE and CYP51 by eugenol conferring inhibition of Candida albicans: Computationally curated study with experimental validation.
Jignesh Prajapati, Dweipayan Goswami, Milan Dabhi, Dhaval Acharya, Rakesh M Rawal

Comput Biol Med· December 2022

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A Comprehensive in vitro and in silico Assessment on Inhibition of CYP51B and Ergosterol Biosynthesis by Eugenol in Rhizopus oryzae.
Jignesh Prajapati, Priyashi Rao, Lipi Poojara, Dhaval Acharya, Saumya K Patel

Curr Microbiol· December 2022

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Interactive bioinformatics analysis for the screening of hub genes and molecular docking of phytochemicals present in kitchen spices to inhibit CDK1 in cervical cancer.
Harsha Vaghasia, Shiralee Sakaria, Jignesh Prajapati, Meenu Saraf, Rakesh M Rawal

Comput Biol Med· October 2022

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Perceiving SARS-CoV-2 Mpro and PLpro dual inhibitors from pool of recognized antiviral compounds of endophytic microbes: an in silico simulation study.
Jignesh Prajapati, Rohit Patel, Priyashi Rao, Meenu Saraf, Rakesh Rawal

Struct Chem· April 2022

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Endophytic fungi: A treasure trove of novel anticancer compounds.
Jignesh Prajapati, Dweipayan Goswami, Rakesh M Rawal

Curr Res Pharmacol Drug Discov· September 2021

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