Publications by authors named "Jinge Gu"

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A simple method for mapping the location of cross-β-forming regions within protein domains of low sequence complexity.
Jinge Gu, Xiaoming Zhou, Lillian Sutherland, Glen Liszczak, Steven L McKnight

Proc Natl Acad Sci U S A· April 2025

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N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine.
Chuchu Wang, Chunyu Zhao, Hu Xiao, Jiali Qiang, Zhenying Liu, Jinge Gu

Elife· December 2024

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Phosphorylation-Regulated Dynamic Phase Separation of HIP-55 Protects Against Heart Failure.
Yunqi Jiang, Jinge Gu, Xiaodou Niu, Jiaojiao Hu, Yongzhen Zhang

Circulation· September 2024

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N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine.
Chuchu Wang, Chunyu Zhao, Xiao Hu, Jiali Qiang, Zhenying Liu, Jinge Gu

bioRxiv· August 2024

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VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates.
Chuchu Wang, Kai Zhang, Bin Cai, Jillian E Haller, Kathryn E Carnazza, Jinge Gu

Nat Cell Biol· August 2024

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Hsp90α forms condensate engaging client proteins with RG motif repeats.
Jiaojiao Hu, Hui Dong, Yichen Li, Jinge Gu, Liang Yang

Chem Sci· July 2024

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Lysophosphatidylcholine binds α-synuclein and prevents its pathological aggregation.
Chunyu Zhao, Jia Tu, Chuchu Wang, Wenbin Liu, Jinge Gu

Natl Sci Rev· June 2024

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Oxidative regulation of TDP-43 self-association by a β-to-α conformational switch.
Jinge Gu, Xiaoming Zhou, Lillian Sutherland, Masato Kato, Klaudia Jaczynska

Proc Natl Acad Sci U S A· October 2023

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Oxidative regulation of TDP-43 self-association by a β-to-α conformational switch.
Jinge Gu, Xiaoming Zhou, Lillian Sutherland, Masato Kato, Klaudia Jaczynska

bioRxiv· August 2023

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Graphene Quantum Dots Modulate Stress Granule Assembly and Prevent Abnormal Phase Transition of Fused in Sarcoma Protein.
Hong Zhang, Jinge Gu, Yiling Zhang, Huazhang Guo, Shengnan Zhang

ACS Nano· June 2023

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A High-Throughput Method to Profile Protein Liquid-Liquid Phase Separation.
Yichen Li, Jinge Gu, Cong Liu, Dan Li

Methods Mol Biol· October 2022

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Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition.
Shan Lu, Jiaojiao Hu, Olubankole Aladesuyi Arogundade, Alexander Goginashvili, Sonia Vazquez-Sanchez, Jinge Gu

Nat Cell Biol· September 2022

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SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation.
Yichen Li, Shuaiyao Lu, Jinge Gu, Wencheng Xia, Shengnan Zhang

Protein Cell· August 2022

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Hyperosmotic-stress-induced liquid-liquid phase separation of ALS-related proteins in the nucleus.
Chao Gao, Jinge Gu, Hong Zhang, Kai Jiang, Linlin Tang

Cell Rep· July 2022

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Hsp70 exhibits a liquid-liquid phase separation ability and chaperones condensed FUS against amyloid aggregation.
Yichen Li, Jinge Gu, Chen Wang, Jiaojiao Hu, Shenqing Zhang

iScience· June 2022

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Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway.
Wenying Zhang, Guang Rong, Jinge Gu, Cuiling Fan, Tingting Guo

FASEB J· March 2022

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Liquid-liquid phase separation of RBGD2/4 is required for heat stress resistance in Arabidopsis.
Shaobo Zhu, Jinge Gu, Juanjuan Yao, Yichen Li, Zheting Zhang, Xinrui Gui

Dev Cell· March 2022

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Molecular structure of an amyloid fibril formed by FUS low-complexity domain.
Yunpeng Sun, Shenqing Zhang, Jiaojiao Hu, Youqi Tao, Wencheng Xia, Jinge Gu

iScience· January 2022

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Hsp70 chaperones TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation.
Jinge Gu, Chen Wang, Rirong Hu, Yichen Li, Shengnan Zhang

Cell Res· September 2021

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Hsp40 proteins phase separate to chaperone the assembly and maintenance of membraneless organelles.
Jinge Gu, Zhenying Liu, Shengnan Zhang, Yichen Li, Wencheng Xia

Proc Natl Acad Sci U S A· December 2020

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The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure.
Yunpeng Sun, Kun Zhao, Wencheng Xia, Guoqin Feng, Jinge Gu, Xinrui Gui

Nat Commun· December 2020

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Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation.
Chen Wang, Yongjia Duan, Gang Duan, Qiangqiang Wang, Kai Zhang, Jinge Gu, Lin Guo

Mol Cell· August 2020

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Ambient fine particulate matter exposure perturbed circadian rhythm and oscillations of lipid metabolism in adipose tissues.
Yixuan Wang, Ran Li, Rucheng Chen, Weijia Gu, Lu Zhang, Jinge Gu

Chemosphere· July 2020

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Factors Influencing the Interactions in Gelatin/Hydroxyapatite Hybrid Materials.
Zixin Zhang, Kexin Li, Weixian Zhou, Jin'ge Gu, Ying Liu

Front Chem· June 2020

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Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation.
Zhenying Liu, Shengnan Zhang, Jinge Gu, Yilun Tong, Yichen Li, Xinrui Gui

Nat Struct Mol Biol· April 2020

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