Publications by authors named "Jinzhang Chen"

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Camrelizumab Combined with Lenvatinib and RALOX-Hepatic Arterial Infusion Chemotherapy for Unresectable Hepatocellular Carcinoma (Cal Era): A Prospective, Single-Arm, Phase II Trial.
Mengya Zang, Qi Li, Xiaoyun Hu, Huajin Pang, Rong Li, Yongru Chen, Jinzhang Chen

Liver Cancer· December 2025

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SPINK1-driven cellular heterogeneity and interaction networks in intrahepatic cholangiocarcinoma revealed by integrated multi-omics analysis.
Xiaoxiang Rong, Jiayun Guan, Chanqi Ye, Qiong Li, Mingyu Wan, Jinzhang Chen, Ruyin Chen

J Adv Res· November 2025

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Comparison of the efficacy and safety of TACE-HAIC-MTTs-ICIs and TACE-MTTs-ICIs in the hepatocellular carcinoma: a prognostic analysis based on the dynamic changes of serum AFP.
Wenli Li, Mingjian Lu, Guosheng Yuan, Feng Shi, Mengya Zang, Yongru Chen, Jinzhang Chen

Int J Surg· October 2025

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Metabolomics and lipidomics predictor of survival in hepatocellular carcinoma patients receiving tyrosine kinase inhibitor and immune checkpoint inhibitor combination therapy.
Shaoxing Guan, Guosheng Yuan, Tu Xian, Yongru Chen, Ruitong Li, Jinzhang Chen

Drug Metab Dispos· October 2025

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TCR-based cellular immunotherapy for hepatocellular carcinoma: advances, challenges, and prospects.
Wanting Zeng, Wei Zhu, Guosheng Yuan, Jinzhang Chen, Zhanhui Wang

Cancer Immunol Immunother· July 2025

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Genome-wide enhancer-gene regulatory maps of liver reveal novel regulatory mechanisms underlying NAFLD pathogenesis.
Ruofan Li, Kaiyan Su, Tianzhun Wu, Li Xu, Wenyu Song, Jinzhang Chen

BMC Genomics· May 2025

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Multiple-omics analysis reveals a dedifferentiation-immune loop in intrahepatic cholangiocarcinoma.
Jian Ruan, Qiong Li, Yuzhi Jin, Jie Yin, Chanqi Ye, Fei Cheng, Ruyin Chen, Jinzhang Chen

Mol Ther· April 2025

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Low-Level Viremia Impairs Efficacy of Immune Checkpoint Inhibitors in Unresectable Hepatocellular Carcinoma.
Rong Li, Wenli Li, Qing Yang, Yujuan Guan, Yongru Chen, Jinzhang Chen

Liver Int· April 2025

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Treatment of a schizophrenia patient on long-term super-dose antipsychotics: a case report.
Xiaobo Xie, Jinzhang Chen, Hongli Song, Zebin Fan

Front Psychiatry· January 2025

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Development and Validation of a Sensitive LC-MS/MS Method for Determination of Lenvatinib and Its Major Metabolites in Human Plasma and Its Application in Hepatocellular Carcinoma Patients.
Shaoxing Guan, Guosheng Yuan, Guofang Bi, Qingqing Yu, Jian-Hong Fang, Jinzhang Chen

J Sep Sci· December 2024

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Cadonilimab (PD-1/CTLA-4) in combination with lenvatinib in unresectable hepatocellular carcinoma (uHCC): A retrospective real-world study.
Guosheng Yuan, Yongru Chen, Peilin Zhu, Qiong Deng, Kaiyan Su, Jinzhang Chen

Heliyon· October 2024

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Immune checkpoint inhibitors and anti-vascular endothelial growth factor antibody/tyrosine kinase inhibitors with or without transarterial chemoembolization as first-line treatment for advanced hepatocellular carcinoma (CHANCE2201): a target trial emulation study.
Zhi-Cheng Jin, Jian-Jian Chen, Xiao-Li Zhu, Xu-Hua Duan, Yu-Jing Xin, Jin-Zhang Chen, Ting-Song Chen

EClinicalMedicine· June 2024

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A novel engineered IL-21 receptor arms T-cell receptor-engineered T cells (TCR-T cells) against hepatocellular carcinoma.
Wei Zhu, Zhiming Zhang, Jinzhang Chen, Xiaolan Chen, Lei Huang

Signal Transduct Target Ther· April 2024

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Efficacy and safety of tislelizumab plus lenvatinib as first-line treatment in patients with unresectable hepatocellular carcinoma: a multicenter, single-arm, phase 2 trial.
Li Xu, Jinzhang Chen, Chang Liu, Xiaoling Song, Yanqiao Zhang, Minshan Chen

BMC Med· April 2024

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Spleen-dedicated stiffness measurement performed well to rule out high-risk varices in HBV-related hepatocellular carcinoma: Screening for high-risk varices in HCC.
Xiao Cheng, Yujun Tang, Qinjun He, Jiankang Song, Kunyuan Wang, Jinzhang Chen, Jinjun Chen

Aliment Pharmacol Ther· March 2024

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Transarterial chemoembolization with/without immune checkpoint inhibitors plus tyrosine kinase inhibitors for unresectable hepatocellular carcinoma: a single center, propensity score matching real-world study.
Guosheng Yuan, Wenli Li, Mengya Zang, Rong Li, Qi Li, Jinzhang Chen

Discov Oncol· March 2024

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Arterial chemotherapy for hepatocellular carcinoma in China: consensus recommendations.
Ming Zhao, Zhi Guo, Ying-Hua Zou, Xiao Li, Zhi-Ping Yan, Min-Shan Chen, Xiao-Ming Chen, Jin-Zhang Chen

Hepatol Int· February 2024

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Tyrosine kinase inhibitors, immune checkpoint inhibitors combined with hepatic arterial infusion of oxaliplatin and raltitrexed versus oxaliplatin, 5-fluorouracil and leucovorin for intermediate and advanced hepatocellular carcinoma: A retrospective study.
Mengya Zang, Xiaoyun Hu, Guosheng Yuan, Rong Li, Wenli Li, Jinzhang Chen

Int Immunopharmacol· December 2023

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Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV-infected intrahepatic cholangiocarcinoma.
Yifei Shen, Shuaishuai Xu, Chanqi Ye, Qiong Li, Ruyin Chen, Xiaochen Zhang, Jinzhang Chen

iScience· February 2023

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EMLI-ICC: an ensemble machine learning-based integration algorithm for metastasis prediction and risk stratification in intrahepatic cholangiocarcinoma.
Jian Ruan, Shuaishuai Xu, Ruyin Chen, Wenxin Qu, Qiong Li, Xiaochen Zhang, Jinzhang Chen

Brief Bioinform· November 2022

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Characterization of somatic mutations and pathway alterations during hepatocellular carcinoma vascular invasion using next-generation sequencing.
Qi Li, Qifan Zhang, Jinzhang Chen, Mengya Zang, Xiaoyun Hu

J Gastrointest Oncol· August 2022

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[Application of liquid biopsy in early screening and recurrence prediction of hepatocellular carcinoma].
X Hao, S Y Deng, K Y Wang, L Chen, J L Hou, Jinzhang Chen

Zhonghua Gan Zang Bing Za Zhi· August 2022

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Interaction between baseline HBV loads and the prognosis of patients with HCC receiving anti-PD-1 in combination with antiangiogenic therapy undergoing concurrent TAF prophylaxis.
Xiaoyun Hu, Rong Li, Qi Li, Mengya Zang, Guosheng Yuan, Jinzhang Chen

BMC Infect Dis· July 2022

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Hepatic Tumor Stiffness Measured by Shear Wave Elastography Is Prognostic for HCC Progression Following Treatment With Anti-PD-1 Antibodies Plus Lenvatinib: A Retrospective Analysis of Two Independent Cohorts.
Guosheng Yuan, Fuli Xie, Yangda Song, Qi Li, Rong Li, Xiao Cheng, Jinzhang Chen

Front Immunol· June 2022

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Cross talk between acetylation and methylation regulators reveals histone modifier expression patterns posing prognostic and therapeutic implications on patients with colon cancer.
Rui Zhou, Fuli Xie, Kuncai Liu, Xuee Zhou, Xuemei Chen, Jinzhang Chen

Clin Epigenetics· May 2022

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