Publications by authors named "Jiri Simurda"

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Field potential duration and its variability as essential parameters for revealing proarrhythmia: problematic aspects of analysis in cardiomyocytes derived from human pluripotent stem cells.
Martin Král, Olga Švecová, Pavel Jurák, Josef Halámek, Milena Šimurdová

Prog Biophys Mol Biol· December 2025

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Functional consequences of changes in the distribution of Ca extrusion pathways between t-tubular and surface membranes in a model of human ventricular cardiomyocyte.
Michal Pásek, Markéta Bébarová, Milena Šimurdová, Jiří Šimurda

J Mol Cell Cardiol· August 2024

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A new approach to the determination of tubular membrane capacitance: passive membrane electrical properties under reduced electrical conductivity of the extracellular solution.
Jiří Šimurda, Milena Šimurdová, Olga Švecová, Markéta Bébarová

Pflugers Arch· December 2022

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Fraction of the T-Tubular Membrane as an Important Parameter in Cardiac Cellular Electrophysiology: A New Way of Estimation.
Olga Švecová, Markéta Bébarová, Milena Šimurdová, Jiří Šimurda

Front Physiol· May 2022

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Aminophylline at clinically relevant concentrations affects inward rectifier potassium current in a dual way.
Nuno Jorge Dourado Ramalho, Olga Švecová, Roman Kula, Milena Šimurdová, Jiří Šimurda

Pflugers Arch· March 2022

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Divergent estimates of the ratio between Na+-Ca2+ current densities in t-tubular and surface membranes of rat ventricular cardiomyocytes.
Michal Pásek, Jiří Šimurda, Markéta Bébarová, Georges Christé

J Cell Sci· July 2021

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Current density as routine parameter for description of ionic membrane current: is it always the best option?
Roman Kula, Markéta Bébarová, Peter Matejovič, Jiří Šimurda, Michal Pásek

Prog Biophys Mol Biol· November 2020

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A new simple approach to estimation of membrane capacitance from current responses to voltage clamp steps.
Jiří Šimurda, Milena Šimurdová, Olga Švecová

Prog Biophys Mol Biol· November 2020

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Distribution of data in cellular electrophysiology: Is it always normal?
Roman Kula, Markéta Bébarová, Peter Matejovič, Jiří Šimurda, Michal Pásek

Prog Biophys Mol Biol· November 2020

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The intriguing effect of ethanol and nicotine on acetylcholine-sensitive potassium current IKAch: Insight from a quantitative model.
Jiří Šimurda, Milena Šimurdová, Markéta Bébarová

PLoS One· March 2020

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Inward rectifying potassium currents resolved into components: modeling of complex drug actions.
Jiří Šimurda, Milena Šimurdová, Markéta Bébarová

Pflugers Arch· February 2018

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Nicotine at clinically relevant concentrations affects atrial inward rectifier potassium current sensitive to acetylcholine.
Markéta Bébarová, Peter Matejovič, Olga Švecová, Roman Kula, Milena Šimurdová

Naunyn Schmiedebergs Arch Pharmacol· May 2017

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Effect of ethanol at clinically relevant concentrations on atrial inward rectifier potassium current sensitive to acetylcholine.
Markéta Bébarová, Peter Matejovič, Michal Pásek, Zuzana Hořáková, Jan Hošek

Naunyn Schmiedebergs Arch Pharmacol· October 2016

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Acute effects of ethanol on action potential and intracellular Ca(2+) transient in cardiac ventricular cells: a simulation study.
Michal Pásek, Markéta Bébarová, Georges Christé, Milena Šimurdová, Jiří Šimurda

Med Biol Eng Comput· May 2016

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Effect of Ca2+ efflux pathway distribution and exogenous Ca2+ buffers on intracellular Ca2+ dynamics in the rat ventricular myocyte: a simulation study.
Michal Pásek, Jiří Simurda, Clive H Orchard

Biomed Res Int· September 2015

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Effect of ion concentration changes in the limited extracellular spaces on sarcolemmal ion transport and Ca2+ turnover in a model of human ventricular cardiomyocyte.
Dana Hrabcová, Michal Pásek, Jiří Šimurda, Georges Christé

Int J Mol Sci· December 2013

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Estimation of rate constants of drug binding to open channels of cardiac transient outward current.
Jiří Simurda, Milena Simurdová

Gen Physiol Biophys· March 2012

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Effect of antipsychotic drug perphenazine on fast sodium current and transient outward potassium current in rat ventricular myocytes.
Markéta Bébarová, Peter Matejovic, Michal Pásek, Dagmar Jansová, Milena Simurdová, Jirí Simurda

Naunyn Schmiedebergs Arch Pharmacol· August 2009

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A model of the guinea-pig ventricular cardiac myocyte incorporating a transverse-axial tubular system.
Michal Pásek, Jiri Simurda, Clive H Orchard, Georges Christé

Prog Biophys Mol Biol· May 2008

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The functional role of cardiac T-tubules explored in a model of rat ventricular myocytes.
Michal Pásek, Jiri Simurda, Georges Christé

Philos Trans A Math Phys Eng Sci· May 2006

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