Publications by authors named "Jochen Kuhse"

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Is the Activation of the Postsynaptic Ligand Gated Glycine- or GABA Receptors Essential for the Receptor Clustering at Inhibitory Synapses?
Eva Kiss, Joachim Kirsch, Jochen Kuhse, Stefan Kins

Biomedicines· August 2025

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Another Use for a Proven Drug: Experimental Evidence for the Potential of Artemisinin and Its Derivatives to Treat Alzheimer's Disease.
Eva Kiss, Stefan Kins, Karin Gorgas, Kinga Hajnal Venczel Szakács, Joachim Kirsch, Jochen Kuhse

Int J Mol Sci· April 2024

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Loss of Extrasynaptic Inhibitory Glycine Receptors in the Hippocampus of an AD Mouse Model Is Restored by Treatment with Artesunate.
Jochen Kuhse, Femke Groeneweg, Stefan Kins, Karin Gorgas, Ralph Nawrotzki

Int J Mol Sci· February 2023

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Artemisinin-treatment in pre-symptomatic APP-PS1 mice increases gephyrin phosphorylation at Ser270: a modification regulating postsynaptic GABAR density.
Eva Kiss, Stefan Kins, Karin Gorgas, Maret Orlik, Carolin Fischer, Jochen Kuhse

Biol Chem· January 2022

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Binding of gephyrin to microtubules is regulated by its phosphorylation at Ser270.
Lin Zhou, Eva Kiss, Rebecca Demmig, Joachim Kirsch, Ralph Alexander Nawrotzki, Jochen Kuhse

Histochem Cell Biol· July 2021

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Artesunate restores the levels of inhibitory synapse proteins and reduces amyloid-β and C-terminal fragments (CTFs) of the amyloid precursor protein in an AD-mouse model.
Eva Kiss, Stefan Kins, Yasmin Zöller, Sandra Schilling, Karin Gorgas, Jochen Kuhse

Mol Cell Neurosci· June 2021

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Amyloid-β Fosters p35/CDK5 Signaling Contributing to Changes of Inhibitory Synapses in Early Stages of Cerebral Amyloidosis.
Eva Kiss, Femke Groeneweg, Karin Gorgas, Andrea Schlicksupp, Stefan Kins, Jochen Kuhse

J Alzheimers Dis· May 2021

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Early alterations in hippocampal perisomatic GABAergic synapses and network oscillations in a mouse model of Alzheimer's disease amyloidosis.
Jan-Oliver Hollnagel, Shehabeldin Elzoheiry, Karin Gorgas, Stefan Kins, Carlo Antonio Beretta, Jochen Kuhse

PLoS One· September 2019

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Gephyrin: a key regulatory protein of inhibitory synapses and beyond.
Femke L Groeneweg, Christa Trattnig, Jochen Kuhse, Ralph A Nawrotzki, Joachim Kirsch

Histochem Cell Biol· November 2018

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Biphasic Alteration of the Inhibitory Synapse Scaffold Protein Gephyrin in Early and Late Stages of an Alzheimer Disease Model.
Eva Kiss, Karin Gorgas, Andrea Schlicksupp, Dagmar Groß, Stefan Kins, Jochen Kuhse

Am J Pathol· September 2016

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KCC2 knockdown impairs glycinergic synapse maturation in cultured spinal cord neurons.
Chrysovalandis Schwale, Stefanie Schumacher, Claus Bruehl, Stefan Titz, Andrea Schlicksupp, Jochen Kuhse

Histochem Cell Biol· June 2016

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Forebrain-specific loss of synaptic GABAA receptors results in altered neuronal excitability and synaptic plasticity in mice.
Gregory A O'Sullivan, Peter Jedlicka, Hong-Xing Chen, Heba Kalbouneh, Angelo Ippolito, Jochen Kuhse

Mol Cell Neurosci· April 2016

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Cyclin-dependent kinase 5 is involved in the phosphorylation of gephyrin and clustering of GABAA receptors at inhibitory synapses of hippocampal neurons.
Heba Kalbouneh, Andrea Schlicksupp, Joachim Kirsch, Jochen Kuhse

PLoS One· November 2015

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Effects of two elongation factor 1A isoforms on the formation of gephyrin clusters at inhibitory synapses in hippocampal neurons.
Michal Becker, Jochen Kuhse, Joachim Kirsch

Histochem Cell Biol· December 2013

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Phosphorylation of gephyrin in hippocampal neurons by cyclin-dependent kinase CDK5 at Ser-270 is dependent on collybistin.
Jochen Kuhse, Heba Kalbouneh, Andrea Schlicksupp, Susanne Mükusch, Ralph Nawrotzki

J Biol Chem· September 2012

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Effects of distinct collybistin isoforms on the formation of GABAergic synapses in hippocampal neurons.
Christoph Körber, Andrea Richter, Michaela Kaiser, Andrea Schlicksupp, Susanne Mükusch, Jochen Kuhse

Mol Cell Neurosci· July 2012

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Molecular architecture of glycinergic synapses.
Thomas Dresbach, Ralph Nawrotzki, Thomas Kremer, Stefanie Schumacher, Daniel Quinones, Jochen Kuhse

Histochem Cell Biol· October 2008

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Activity-dependent shedding of the NMDA receptor glycine binding site by matrix metalloproteinase 3: a PUTATIVE mechanism of postsynaptic plasticity.
Thorsten Pauly, Miriam Ratliff, Eweline Pietrowski, Rainer Neugebauer, Andrea Schlicksupp, Jochen Kuhse

PLoS One· July 2008

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Components of the translational machinery are associated with juvenile glycine receptors and are redistributed to the cytoskeleton upon aging and synaptic activity.
Raphael Bluem, Enrico Schmidt, Carsten Corvey, Michael Karas, Andrea Schlicksupp, Jochen Kuhse

J Biol Chem· December 2007

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Lipid emulsions reduce NMDA-evoked currents.
Henry Weigt, Michael Georgieff, Cordian Beyer, Eva M Georgieff, Jochen Kuhse

Neuropharmacology· September 2004

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Expression of a soluble glycine binding domain of the NMDA receptor in Escherichia coli.
Rainer Neugebauer, Heinrich Betz, Jochen Kuhse

Biochem Biophys Res Commun· June 2003

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