Publications by authors named "Jochen Lehmann"

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Systems Biology of Aromatic Compound Catabolism in Facultative Anaerobic EbN1.
Patrick Becker, Sarah Kirstein, Daniel Wünsch, Julia Koblitz, Ramona Buschen, Jochen Lehmann

mSystems· December 2022

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Synthesis, Molecular Modeling, and Biological Evaluation of Novel Tetrahydro-β-Carboline Hydantoin and Tetrahydro-β-Carboline Thiohydantoin Derivatives as Phosphodiesterase 5 Inhibitors.
Ashraf H Abadi, Jochen Lehmann, Gary A Piazza, Mohammad Abdel-Halim, Mohamed S M Ali

Int J Med Chem· July 2016

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Spectrofluorimetric determination of dopamine receptor antagonist LE 300 in mice plasma.
Mohamed Hefnawy, Mostafa Mohamed, Mohamed Abunassif, Amer Alanazi, Abdulrahman Al-Majed, Lehmann Jochen

Luminescence· February 2016

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Evaluation of Homobivalent Carbolines as Designed Multiple Ligands for the Treatment of Neurodegenerative Disorders.
Robert Otto, Robert Penzis, Friedemann Gaube, Oliver Adolph, Karl J Föhr, Jochen Lehmann

J Med Chem· August 2015

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Selective microemulsion liquid chromatography analysis of dopamine receptor antagonist LE300 and its N-methyl metabolite in mouse sera by using a monolithic silica column.
Abdulrhman A Al-Majed, Mohamed M Hefnawy, Mostafa S Mohammed, Sabry M Attia, Jochen Lehmann

J Chromatogr B Analyt Technol Biomed Life Sci· May 2015

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Beta and gamma carboline derivatives as potential anti-Alzheimer agents: A comparison.
Robert Otto, Robert Penzis, Friedemann Gaube, Thomas Winckler, Dorothea Appenroth, Jochen Lehmann

Eur J Med Chem· November 2014

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Tacrine-flurbiprofen hybrids as multifunctional drug candidates for the treatment of Alzheimer's disease.
Yao Chen, Jianfei Sun, Sixun Peng, Hong Liao, Yihua Zhang, Jochen Lehmann

Arch Pharm (Weinheim)· December 2013

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An interactive SAR approach to discover novel hybrid thieno probes as ligands for D2-like receptors with affinities in the subnanomolar range.
Mohamed A O Abdel-Fattah, Jochen Lehmann, Ashraf H Abadi

Chem Biodivers· December 2013

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Discovery of highly potent and selective D4 ligands by interactive SAR study.
Mohamed A O Abdelfattah, Jochen Lehmann, Ashraf H Abadi

Bioorg Med Chem Lett· September 2013

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NO-donating tacrine derivatives as potential butyrylcholinesterase inhibitors with vasorelaxation activity.
Yao Chen, Jianfei Sun, Zhangjian Huang, Hong Liao, Sixun Peng, Jochen Lehmann

Bioorg Med Chem Lett· June 2013

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Design, synthesis and evaluation of tacrine-flurbiprofen-nitrate trihybrids as novel anti-Alzheimer's disease agents.
Yao Chen, Jianfei Sun, Zhangjian Huang, Hong Liao, Sixun Peng, Jochen Lehmann

Bioorg Med Chem· May 2013

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Discovery of a novel acetylcholinesterase inhibitor by structure-based virtual screening techniques.
Yao Chen, Lei Fang, Sixun Peng, Hong Liao, Jochen Lehmann

Bioorg Med Chem Lett· May 2012

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Tacrine-ferulic acid-nitric oxide (NO) donor trihybrids as potent, multifunctional acetyl- and butyrylcholinesterase inhibitors.
Yao Chen, Jianfei Sun, Lei Fang, Mei Liu, Sixun Peng, Jochen Lehmann

J Med Chem· May 2012

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Chiral indolo[3,2-f][3]benzazecine-type dopamine receptor antagonists: synthesis and activity of racemic and enantiopure derivatives.
Dina Robaa, Christoph Enzensperger, Shams Eldin Abulazm, Mohamed M Hefnawy, Hussein I El-Subbagh, Jochen Lehmann

J Med Chem· October 2011

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Interaction of ionic liquids ions with natural cyclodextrins.
Daniel Ondo, Marcela Tkadlecová, Vladimír Dohnal, Jakub Rak, Jaroslav Kvíčala, Jochen K Lehmann

J Phys Chem B· September 2011

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The influence of hydrogen bonding on the physical properties of ionic liquids.
Koichi Fumino, Tim Peppel, Monika Geppert-Rybczyńska, Dzmitry H Zaitsau, Jochen K Lehmann

Phys Chem Chem Phys· August 2011

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Effects of ginger constituents on the gastrointestinal tract: role of cholinergic M3 and serotonergic 5-HT3 and 5-HT4 receptors.
Heinz H Pertz, Jochen Lehmann, René Roth-Ehrang, Sigurd Elz

Planta Med· July 2011

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A novel non-phenolic dibenzazecine derivative with nanomolar affinities for dopamine receptors.
Dina Robaa, Shams Eldin AbulAzm, Jochen Lehmann, Christoph Enzensperger

Chem Biodivers· March 2011

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Arylalkylamine-, beta-carboline-, quinolizine- and azecine-derived compounds and their in vitro interaction with the ionotropic 5-HT3 receptor: search for new lead structures.
Christoph Enzensperger, Jochen Lehmann, Katrin von Schroetter, Anja Riyazi, Eugen J Verspohl

Arzneimittelforschung· January 2011

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Residues at the indole-NH of LE300 modulate affinities and selectivities for dopamine receptors.
Dina Robaa, Robert Kretschmer, Oliver Siol, Shams Eldin Abulazm, Elsayeda Elkhawass, Jochen Lehmann

Arch Pharm (Weinheim)· January 2011

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Cardioprotective effect of NO-metoprolol in murine coxsackievirus B3-induced myocarditis.
Brigitte Glück, Katja Dahlke, Roland Zell, Andi Krumbholz, Michael Decker, Jochen Lehmann

J Med Virol· December 2010

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A novel class of nitrovasodilators: potency and in vitro tolerance of organic aminoalkylnitrates.
Carolin Roegler, Andreas König, Erika Glusa, Jochen Lehmann

J Cardiovasc Pharmacol· November 2010

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Investigation into the in vivo effects of five novel tacrine/ferulic acid and beta-carboline derivatives on scopolamine-induced cognitive impairment in rats using radial maze paradigm.
Christian Fleck, Dorothea Appenroth, Lei Fang, Yvonne Schott, Jochen Lehmann

Arzneimittelforschung· September 2010

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Low-viscosity paramagnetic ionic liquids with doubly charged [Co(NCS)4]2- ions.
Tim Peppel, Martin Köckerling, Monika Geppert-Rybczyńska, Ricardas V Ralys, Jochen K Lehmann

Angew Chem Int Ed Engl· September 2010

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[Medicinal chemistry of nitrates and PDE5 inhibitors].
Carolin Roegler, Jochen Lehmann

Pharm Unserer Zeit· September 2010

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