Publications by authors named "Jock Findlay"

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Three-Dimensional Models of Implantation Using Human Stem Cells: Scientific Insights and Broader Considerations.
Megan Munsie, Jock K Findlay

Biomolecules· July 2025

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Knock down of TIMP-2 by siRNA and CRISPR/Cas9 mediates diverse cellular reprogramming of metastasis and chemosensitivity in ovarian cancer.
Ruth M Escalona, Simon Chu, Elif Kadife, Jason K Kelly, George Kannourakis, Jock K Findlay

Cancer Cell Int· December 2022

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Expression of TIMPs and MMPs in Ovarian Tumors, Ascites, Ascites-Derived Cells, and Cancer Cell Lines: Characteristic Modulatory Response Before and After Chemotherapy Treatment.
Ruth M Escalona, George Kannourakis, Jock K Findlay, Nuzhat Ahmed

Front Oncol· January 2022

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DNA repair in primordial follicle oocytes following cisplatin treatment.
Quynh-Nhu Nguyen, Nadeen Zerafa, Jock K Findlay, Martha Hickey, Karla J Hutt

J Assist Reprod Genet· June 2021

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TIMP-2 regulates proliferation, invasion and STAT3-mediated cancer stem cell-dependent chemoresistance in ovarian cancer cells.
Ruth M Escalona, Maree Bilandzic, Patrick Western, Elif Kadife, George Kannourakis, Jock K Findlay

BMC Cancer· October 2020

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Reproductive science and the future of the planet.
Jock K Findlay, Michael K Holland, Bob B M Wong

Reproduction· September 2019

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Oocytes from stem cells.
Urooza C Sarma, Jock K Findlay, Karla J Hutt

Best Pract Res Clin Obstet Gynaecol· February 2019

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Paclitaxel-Induced Src Activation Is Inhibited by Dasatinib Treatment, Independently of Cancer Stem Cell Properties, in a Mouse Model of Ovarian Cancer.
Elif Kadife, Emily Chan, Rodney Luwor, George Kannourakis, Jock Findlay

Cancers (Basel)· February 2019

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Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility.
Quynh-Nhu Nguyen, Nadeen Zerafa, Seng H Liew, F Hamish Morgan, Andreas Strasser, Jock K Findlay

Cell Death Dis· May 2018

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Momelotinib decreased cancer stem cell associated tumor burden and prolonged disease-free remission period in a mouse model of human ovarian cancer.
Emily Chan, Rodney Luwor, Christopher Burns, George Kannourakis, Jock K Findlay

Oncotarget· March 2018

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The Many Facets of Metzincins and Their Endogenous Inhibitors: Perspectives on Ovarian Cancer Progression.
Ruth M Escalona, Emily Chan, George Kannourakis, Jock K Findlay, Nuzhat Ahmed

Int J Mol Sci· February 2018

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The ovarian reserve is depleted during puberty in a hormonally driven process dependent on the pro-apoptotic protein BMF.
Seng H Liew, Quynh-Nhu Nguyen, Andreas Strasser, Jock K Findlay, Karla J Hutt

Cell Death Dis· August 2017

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Knockdown of stem cell regulator Oct4A in ovarian cancer reveals cellular reprogramming associated with key regulators of cytoskeleton-extracellular matrix remodelling.
Chantel Samardzija, David W Greening, Ruth Escalona, Maoshan Chen, Maree Bilandzic, Jock K Findlay

Sci Rep· April 2017

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Endogenous inhibins regulate steroidogenesis in mouse TM3 Leydig cells by altering SMAD2 signalling.
Yao Wang, Maree Bilandzic, Guck T Ooi, Jock K Findlay, Kaye L Stenvers

Mol Cell Endocrinol· November 2016

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Coalition of Oct4A and β1 integrins in facilitating metastasis in ovarian cancer.
Chantel Samardzija, Rodney B Luwor, Michael A Quinn, George Kannourakis, Jock K Findlay

BMC Cancer· July 2016

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Unique proteome signature of post-chemotherapy ovarian cancer ascites-derived tumor cells.
Nuzhat Ahmed, David Greening, Chantel Samardzija, Ruth M Escalona, Maoshan Chen, Jock K Findlay

Sci Rep· July 2016

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BCL2-modifying factor promotes germ cell loss during murine oogenesis.
Kavitha Vaithiyanathan, Seng H Liew, Nadeen Zerafa, Thilini Gamage, Michele Cook, Jock K Findlay

Reproduction· May 2016

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A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer.
Chantel Samardzija, Rodney B Luwor, Mila Volchek, Michael A Quinn, Jock K Findlay

Mol Cancer· August 2015

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Betaglycan blocks metastatic behaviors in human granulosa cell tumors by suppressing NFκB-mediated induction of MMP2.
Maree Bilandzic, Yao Wang, Nuzhat Ahmed, Rodney B Luwor, Hong Jian Zhu, Jock K Findlay

Cancer Lett· November 2014

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Ovarian cancer stem cells: Molecular concepts and relevance as therapeutic targets.
Nuzhat Ahmed, Khalid Abubaker, Jock K Findlay

Mol Aspects Med· October 2014

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PUMA regulates germ cell loss and primordial follicle endowment in mice.
Michelle Myers, F Hamish Morgan, Seng H Liew, Nadeen Zerafa, Thilini Upeksha Gamage, Jock K Findlay

Reproduction· August 2014

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Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden.
Khalid Abubaker, Rodney B Luwor, Hongjian Zhu, Orla McNally, Michael A Quinn, Jock K Findlay

BMC Cancer· May 2014

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Loss of the proapoptotic BH3-only protein BCL-2 modifying factor prolongs the fertile life span in female mice.
Seng H Liew, Kavitha Vaithiyanathan, Michele Cook, Philippe Bouillet, Clare L Scott, Jock K Findlay

Biol Reprod· April 2014

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Targeted Disruption of the JAK2/STAT3 Pathway in Combination with Systemic Administration of Paclitaxel Inhibits the Priming of Ovarian Cancer Stem Cells Leading to a Reduced Tumor Burden.
Khalid Abubaker, Rodney B Luwor, Ruth Escalona, Orla McNally, Michael A Quinn, Jock K Findlay

Front Oncol· April 2014

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Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden.
Khalid Abubaker, Ardian Latifi, Rod Luwor, Simon Nazaretian, Hongjian Zhu, Jock K Findlay

Mol Cancer· March 2013

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