Publications by authors named "Joe Wu"

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Implementing an Electronic Health Record-Integrated Pediatric Primary Care Sleep Screener.
Ariel A Williamson, Maura Powell, Anthony Luberti, Gregory Lawton, Jungwon Min, Joe Wu, Eberechukwu A Uwah

JAMA Netw Open· August 2025

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Modeling the distribution and progression of motor ability among children with cerebral palsy: An analysis of three reference centile sets.
Rachel Sanderlin, Charlotte Schluger, Joe Wu, Francis Ang Eusebio, Amy L Roberts

Heliyon· December 2024

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Taming multiple binding poses in alchemical binding free energy prediction: the β-cyclodextrin host-guest SAMPL9 blinded challenge.
Sheenam Khuttan, Solmaz Azimi, Joe Z Wu, Sebastian Dick, Chuanjie Wu

Phys Chem Chem Phys· September 2023

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Fact-checking chronotherapeutic research: Commentary on Bisdounis, et al. (2022).
Dorothy Sit, Joe C Wu, John F Gottlieb

Neurosci Biobehav Rev· June 2022

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Relative Binding Free Energy Calculations for Ligands with Diverse Scaffolds with the Alchemical Transfer Method.
Solmaz Azimi, Sheenam Khuttan, Joe Z Wu, Rajat K Pal, Emilio Gallicchio

J Chem Inf Model· January 2022

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Application of the alchemical transfer and potential of mean force methods to the SAMPL8 host-guest blinded challenge.
Solmaz Azimi, Joe Z Wu, Sheenam Khuttan, Tom Kurtzman, Nanjie Deng

J Comput Aided Mol Des· January 2022

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Alchemical Transfer Approach to Absolute Binding Free Energy Estimation.
Joe Z Wu, Solmaz Azimi, Sheenam Khuttan, Nanjie Deng, Emilio Gallicchio

J Chem Theory Comput· June 2021

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Alchemical transformations for concerted hydration free energy estimation with explicit solvation.
Sheenam Khuttan, Solmaz Azimi, Joe Z Wu, Emilio Gallicchio

J Chem Phys· February 2021

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Genomic characterization of the adolescent idiopathic scoliosis-associated transcriptome and regulome.
Nadja Makki, Jingjing Zhao, Zhaoyang Liu, Walter L Eckalbar, Aki Ushiki, Joe Wu

Hum Mol Genet· January 2021

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Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.
Han Dai, April W Case, Thomas V Riera, Thomas Considine, Jessica E Lee, Bo Wu, Joe C Wu

Nat Commun· July 2015

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HIF-1α in the heart: remodeling nucleotide metabolism.
Joe Wu, Cherie Bond, Ping Chen, Minghua Chen, Ying Li

J Mol Cell Cardiol· May 2015

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HIF-1α in heart: protective mechanisms.
Joe Wu, Ping Chen, Ying Li, Chris Ardell, Tatyana Der

Am J Physiol Heart Circ Physiol· September 2013

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Protein kinase inhibitors: breakthrough medicines and the next generation.
Tomi K Sawyer, Joe C Wu, Jonathon R Sawyer, Jessie M English

Expert Opin Investig Drugs· June 2013

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Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5.
Jenny X Chen, Markus Krane, Marcus-Andre Deutsch, Li Wang, Moshe Rav-Acha, Joe C Wu, Sean M Wu

Circ Res· June 2012

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Molecular mechanisms of drug resistance in tyrosine kinases cAbl and cKit.
Jonathan P DiNitto, Joe C Wu

Crit Rev Biochem Mol Biol· August 2011

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Enhanced selectivity profile of pyrazole-urea based DFG-out p38alpha inhibitors.
Hu Liu, Cyrille Kuhn, Frederic Feru, Suzanne L Jacques, Gayatri D Deshmukh, Joe C Wu

Bioorg Med Chem Lett· August 2010

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Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry.
Hui-Min Zhang, Xiu Yu, Michael J Greig, Ketan S Gajiwala, Joe C Wu

Protein Sci· April 2010

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Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance.
Jonathan P DiNitto, Gayatri D Deshmukh, Yan Zhang, Suzanne L Jacques, Rocco Coli, Joe C Wu

J Biochem· April 2010

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Continuous fluorescence-based method for assessing dicer cleavage efficiency reveals 3' overhang nucleotide preference.
Jonathan P DiNitto, Leyu Wang, Joe C Wu

Biotechniques· April 2010

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The design, synthesis and potential utility of fluorescence probes that target DFG-out conformation of p38alpha for high throughput screening binding assay.
Haile Tecle, Frederic Feru, Hu Liu, Cyrille Kuhn, Glen Rennie, Joe C Wu

Chem Biol Drug Des· December 2009

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KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients.
Ketan S Gajiwala, Joe C Wu, James Christensen, Gayatri D Deshmukh, Wade Diehl

Proc Natl Acad Sci U S A· February 2009

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Beyond the MEK-pocket: can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK?
Haile Tecle, Jianxing Shao, Yanhong Li, Michael Kothe, Steven Kazmirski, Joe Wu

Bioorg Med Chem Lett· January 2009

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First-in-class pan caspase inhibitor developed for the treatment of liver disease.
Steven D Linton, Teresa Aja, Robert A Armstrong, Xu Bai, Long-Shiuh Chen, Joe C Wu

J Med Chem· November 2005

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Structure-activity relationships within a series of caspase inhibitors. Part 2: Heterocyclic warheads.
Brett R Ullman, Teresa Aja, Ning Chen, Jose-Luis Diaz, Xin Gu, Joe C Wu

Bioorg Med Chem Lett· August 2005

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Caspase inhibition reduces tubular apoptosis and proliferation and slows disease progression in polycystic kidney disease.
Yunxia Tao, Jun Kim, Sarah Faubel, Joe C Wu, Sandor A Falk

Proc Natl Acad Sci U S A· May 2005

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