Publications by authors named "Joel D Parry"

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Opportunities for More Tailored Approaches to Genotoxicity Testing and Carcinogenicity Strategy for Oligonucleotide Therapeutics: Outcome of an Industry Survey.
Joel D Parry, Tod A Harper, Patrik Andersson, Joanne M Elloway, Natalie S Holman

Nucleic Acid Ther· February 2025

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Outcomes of the European Federation of Pharmaceutical Industries and Associations Oligonucleotide Working Group Survey on Nonclinical Practices and Regulatory Expectations for Therapeutic Oligonucleotide Safety Assessment.
Yann Tessier, William Achanzar, Lauren Mihalcik, Chidozie Amuzie, Patrik Andersson, Joel D Parry

Nucleic Acid Ther· February 2021

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Strategies for In Vivo Screening and Mitigation of Hepatotoxicity Associated with Antisense Drugs.
Piotr J Kamola, Klio Maratou, Paul A Wilson, Kay Rush, Tanya Mullaney, Joel D Parry

Mol Ther Nucleic Acids· September 2017

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In silico and in vitro evaluation of exonic and intronic off-target effects form a critical element of therapeutic ASO gapmer optimization.
Piotr J Kamola, Jeremy D A Kitson, Gemma Turner, Klio Maratou, Sofie Eriksson, Joel D Parry

Nucleic Acids Res· October 2015

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Challenges for inhaled drug discovery and development: Induced alveolar macrophage responses.
Ben Forbes, Raegan O'Lone, Philippa Pribul Allen, Anthony Cahn, Chris Clarke, Joel D Parry

Adv Drug Deliv Rev· May 2014

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Clinical expert panel on monitoring potential lung toxicity of inhaled oligonucleotides: consensus points and recommendations.
Eric W Alton, Homer A Boushey, Holger Garn, Francis H Green, Michael Hodges, Joel D Parry

Nucleic Acid Ther· August 2012

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Doxorubicin in vivo rapidly alters expression and translation of myocardial electron transport chain genes, leads to ATP loss and caspase 3 activation.
Amy V Pointon, Tracy M Walker, Kate M Phillips, Jinli Luo, Joan Riley, Joel D Parry

PLoS One· September 2010

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Pivotal role for two electron reduction in 2,3-dimethoxy-1,4-naphthoquinone and 2-methyl-1,4-naphthoquinone metabolism and kinetics in vivo that prevents liver redox stress.
Joel D Parry, Amy V Pointon, Ursula Lutz, Friederike Teichert, Joanne K Charlwood

Chem Res Toxicol· April 2009

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