Publications by authors named "Johan Grooten"

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Recognition by Dendritic Cells Negatively Regulates Allergic Lung Inflammation through a TLR2/MyD88 Pathway.
Pauline Percier, Sofie De Prins, Giresse Tima, Rudi Beyaert, Johan Grooten

Am J Respir Cell Mol Biol· January 2021

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Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties.
Bo Lou, Ans De Beuckelaer, George R Dakwar, Katrien Remaut, Johan Grooten

J Control Release· August 2018

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Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes.
Lien Van Hoecke, Sandra Van Lint, Kenny Roose, Alexander Van Parys, Peter Vandenabeele, Johan Grooten

Nat Commun· August 2018

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Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide.
Vimal K Udhayakumar, Ans De Beuckelaer, Joanne McCaffrey, Cian M McCrudden, Jonathan L Kirschman, Johan Grooten

Adv Healthc Mater· July 2017

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Mycolates of modulate the flow of cholesterol for bacillary proliferation in murine macrophages.
Ilke Vermeulen, Mark Baird, Juma Al-Dulayymi, Muriel Smet, Jan Verschoor, Johan Grooten

J Lipid Res· April 2017

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Type I Interferons Modulate CD8 T Cell Immunity to mRNA Vaccines.
Ans De Beuckelaer, Johan Grooten, Stefaan De Koker

Trends Mol Med· March 2017

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Type I Interferons Interfere with the Capacity of mRNA Lipoplex Vaccines to Elicit Cytolytic T Cell Responses.
Ans De Beuckelaer, Charlotte Pollard, Sandra Van Lint, Kenny Roose, Lien Van Hoecke, Johan Grooten

Mol Ther· November 2016

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Mycobacterium tuberculosis-associated synthetic mycolates differentially exert immune stimulatory adjuvant activity.
Muriel Smet, Charlotte Pollard, Ans De Beuckelaer, Lien Van Hoecke, Seppe Vander Beken, Johan Grooten

Eur J Immunol· September 2016

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Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines.
Laure Lambricht, Kevin Vanvarenberg, Ans De Beuckelaer, Lien Van Hoecke, Johan Grooten

Mol Ther· September 2016

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Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice.
Muriel Smet, Lien Van Hoecke, Ans De Beuckelaer, Seppe Vander Beken, Thomas Naessens, Johan Grooten

Immun Inflamm Dis· September 2016

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pH-Degradable Mannosylated Nanogels for Dendritic Cell Targeting.
Ruben De Coen, Nane Vanparijs, Martijn D P Risseeuw, Lien Lybaert, Benoit Louage, Johan Grooten

Biomacromolecules· July 2016

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pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation.
Lutz Nuhn, Nane Vanparijs, Ans De Beuckelaer, Lien Lybaert, Glenn Verstraete, Johan Grooten

Proc Natl Acad Sci U S A· July 2016

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Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity.
Tania Løve Aaes, Agnieszka Kaczmarek, Tinneke Delvaeye, Bram De Craene, Stefaan De Koker, Johan Grooten

Cell Rep· April 2016

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Boosting in planta production of antigens derived from the porcine reproductive and respiratory syndrome virus (PRRSV) and subsequent evaluation of their immunogenicity.
Robin Piron, Stefaan De Koker, Annelies De Paepe, Julie Goossens, Johan Grooten

PLoS One· March 2016

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GM-CSF treatment prevents respiratory syncytial virus-induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation.
Thomas Naessens, Bert Schepens, Muriel Smet, Charlotte Pollard, Lien Van Hoecke, Johan Grooten

J Allergy Clin Immunol· March 2016

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Engineering Polymer Hydrogel Nanoparticles for Lymph Node-Targeted Delivery.
Stefaan De Koker, Jiwei Cui, Nane Vanparijs, Lorenzo Albertazzi, Johan Grooten

Angew Chem Int Ed Engl· January 2016

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Spontaneous Protein Adsorption on Graphene Oxide Nanosheets Allowing Efficient Intracellular Vaccine Protein Delivery.
Hui Li, Kaat Fierens, Zhiyue Zhang, Nane Vanparijs, Martijn J Schuijs, Johan Grooten

ACS Appl Mater Interfaces· January 2016

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Hybrid pulmonary surfactant-coated nanogels mediate efficient in vivo delivery of siRNA to murine alveolar macrophages.
Lynn De Backer, Thomas Naessens, Stefaan De Koker, Elisa Zagato, Jo Demeester, Johan Grooten

J Control Release· November 2015

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E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo.
Jan Van den Bossche, Damya Laoui, Thomas Naessens, Hermelijn H Smits, Cornelis H Hokke, Johan Grooten

Sci Rep· July 2015

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The site of administration influences both the type and the magnitude of the immune response induced by DNA vaccine electroporation.
Gaëlle Vandermeulen, Kevin Vanvarenberg, Ans De Beuckelaer, Stefaan De Koker, Laure Lambricht, Johan Grooten

Vaccine· June 2015

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Nanoporous polyelectrolyte vaccine microcarriers. A formulation platform for enhancing humoral and cellular immune responses.
Stefaan De Koker, Kaat Fierens, Marijke Dierendonck, Riet De Rycke, Bart N Lambrecht, Johan Grooten

J Control Release· December 2014

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Challenges and advances towards the rational design of mRNA vaccines.
Charlotte Pollard, Stefaan De Koker, Xavier Saelens, Guido Vanham, Johan Grooten

Trends Mol Med· December 2013

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M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.
Lorena Itatí Ibañez, Kenny Roose, Marina De Filette, Michael Schotsaert, Jessica De Sloovere, Johan Grooten

PLoS One· September 2013

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IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells.
Tom L Van Belle, Hans Dooms, Tom Boonefaes, Xiao-Qing Wei, Georges Leclercq, Johan Grooten

PLoS One· February 2013

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Clinical procedure for colon carcinoma tissue sampling directly affects the cancer marker-capacity of VEGF family members.
Sarah Pringels, Nancy Van Damme, Bram De Craene, Piet Pattyn, Wim Ceelen, Johan Grooten

BMC Cancer· November 2012

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