Publications by authors named "Johan Rockberg"

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Heterogeneity in an adeno-associated virus transfection-based production process limits the production efficiency.
Brian Ladd, Sofia Tunmats, Torbjörn Gräslund, Olalekan Daramola, Johan Rockberg

Sci Rep· November 2025

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Deciphering the determinants of recombinant protein expression across the human secretome.
Helen O Masson, Pablo Di Giusto, Chih-Chung Kuo, Magdalena Malm, Magnus Lundqvist, Johan Rockberg

Proc Natl Acad Sci U S A· October 2025

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Deep sequencing combined with high-throughput screening enables efficient development of a pH-dependent high-affinity binding domain targeting HER3.
Marit Möller, Malin Jönsson, Magnus Lundqvist, Johan Rockberg, John Löfblom

Protein Sci· August 2025

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An Overview of Epitopes and Methods for Antibody Epitope Mapping.
Johan Nilvebrant, Niklas Berndt Thalén, Johan Rockberg, Magdalena Malm

Methods Mol Biol· July 2025

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Mammalian Cell Display with Automated Oligo Design and Library Assembly Allows for Rapid Residue Level Conformational Epitope Mapping.
Niklas Berndt Thalén, Maximilian Karlander, Magdalena Malm, Johan Rockberg

Methods Mol Biol· July 2025

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Epitope Mapping of Antibodies Using Bacterial Cell Surface Display of Gene Fragment Libraries.
Anna-Luisa Volk, Francis Jingxin Hu, Magdalena Malm, Johan Rockberg

Methods Mol Biol· July 2025

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Mapping of Antibody Structural Epitopes Using Bacterial Cell Surface Display of Folded Domains.
Anna-Luisa Volk, Johan Rockberg

Methods Mol Biol· July 2025

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Intensification of rAAV Production Based on HEK293 Cell Transient Transfection.
Ye Zhang, Emil Sundäng Peters, Olalekan Daramola, Trudy Ann Tucker, Johan Rockberg

Biotechnol J· June 2025

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A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice.
Aman Mebrahtu, Ida Laurén, Rosanne Veerman, Gözde Güclüler Akpinar, Martin Lord, Johan Rockberg

Nat Commun· November 2024

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Mammalian cell display with automated oligo design and library assembly allows for rapid residue level conformational epitope mapping.
Niklas Berndt Thalén, Maximilian Karlander, Magnus Lundqvist, Helena Persson, Camilla Hofström, Johan Rockberg

Commun Biol· July 2024

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Co-culture platform for tuning of cancer receptor density allows for evaluation of bispecific immune cell engagers.
Aman Mebrahtu, Gustav Aniander, Alessandro Mega, Mona Moradi Barzadd, Niklas Berndt Thalén, Johan Rockberg

N Biotechnol· March 2024

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Tuning of CHO secretional machinery improve activity of secreted therapeutic sulfatase 150-fold.
Niklas Berndt Thalén, Mona Moradi Barzadd, Magnus Lundqvist, Johanna Rodhe, Monica Andersson, Johan Rockberg

Metab Eng· January 2024

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A PDGFRB- and CD40-targeting bispecific AffiMab induces stroma-targeted immune cell activation.
Alessandro Mega, Aman Mebrahtu, Gustav Aniander, Eva Ryer, Annette Sköld, Johan Rockberg

MAbs· June 2023

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An easy-to-use high-throughput selection system for the discovery of recombinant protein binders from alternative scaffold libraries.
Marit Möller, Malin Jönsson, Magnus Lundqvist, Blenda Hedin, Louise Larsson, Johan Rockberg

Protein Eng Des Sel· January 2023

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CaRA - A multi-purpose phage display library for selection of calcium-regulated affinity proteins.
Malin Jönsson, Julia Scheffel, Emma Larsson, Marit Möller, Gabriella Rossi, Johan Rockberg

N Biotechnol· December 2022

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Correction to "Small Bispecific Affinity Proteins for Simultaneous Target Binding and Albumin-Associated Half-Life Extension".
Emma von Witting, Sarah Lindbo, Magnus Lundqvist, Marit Möller, Andreas Wisniewski, Johan Rockberg

Mol Pharm· September 2022

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Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins.
Magdalena Malm, Chih-Chung Kuo, Mona Moradi Barzadd, Aman Mebrahtu, Num Wistbacka, Johan Rockberg

Metab Eng· July 2022

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Enhanced metabolism and negative regulation of ER stress support higher erythropoietin production in HEK293 cells.
Rasool Saghaleyni, Magdalena Malm, Noah Moruzzi, Jan Zrimec, Ronia Razavi, Johan Rockberg

Cell Rep· June 2022

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Autophagy and intracellular product degradation genes identified by systems biology analysis reduce aggregation of bispecific antibody in CHO cells.
Mona Moradi Barzadd, Magnus Lundqvist, Claire Harris, Magdalena Malm, Anna-Luisa Volk, Johan Rockberg

N Biotechnol· May 2022

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Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells.
Mei Ding, Rajneesh Malhotra, Tomas Ottosson, Magnus Lundqvist, Aman Mebrahtu, Johan Rockberg

Sci Rep· August 2021

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Bispecific Antibody Molecule Inhibits Tumor Cell Proliferation More Efficiently Than the Two-Molecule Combination.
Anna-Luisa Volk, Aman Mebrahtu, Bong-Kook Ko, Magnus Lundqvist, Maximilian Karlander, Johan Rockberg

Drugs R D· June 2021

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Author Correction: Evolution from adherent to suspension: systems biology of HEK293 cell line development.
Magdalena Malm, Rasool Saghaleyni, Magnus Lundqvist, Marco Giudici, Veronique Chotteau, Johan Rockberg

Sci Rep· March 2021

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Ancestral lysosomal enzymes with increased activity harbor therapeutic potential for treatment of Hunter syndrome.
Natalie M Hendrikse, Anna Sandegren, Tommy Andersson, Jenny Blomqvist, Åsa Makower, Johan Rockberg

iScience· March 2021

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Small Bispecific Affinity Proteins for Simultaneous Target Binding and Albumin-Associated Half-Life Extension.
Emma von Witting, Sarah Lindbo, Magnus Lundqvist, Marit Möller, Andreas Wisniewski, Johan Rockberg

Mol Pharm· January 2021

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Evolution from adherent to suspension: systems biology of HEK293 cell line development.
Magdalena Malm, Rasool Saghaleyni, Magnus Lundqvist, Marco Giudici, Veronique Chotteau, Johan Rockberg

Sci Rep· November 2020

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