Publications by authors named "Johan Ruud"

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Inhibition of GCKIII kinases STK25 and MST3 mitigates organ lipotoxicity and enhances metabolic resilience under nutritional stress.
Emma Andersson, Xiangdong Gongye, Emmelie Cansby, Jingjing Zhang, Mara Caputo, Johan Ruud

BMC Med· September 2025

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Semaglutide effects on energy balance are mediated by Adcyap1 neurons in the dorsal vagal complex.
Júlia Teixidor-Deulofeu, Sebastian Blid Sköldheden, Ferran Font-Gironès, Andrej Feješ, Johan Ruud, Linda Engström Ruud

Cell Metab· July 2025

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Ablation of PI3Kγ in neurons protects mice from diet-induced obesity MASLD and insulin resistance.
Angela Molinaro, Arianna Mazzoli, Andrea Usseglio Gaudi, Amit Chand Gupta, Vagner Ramon Rodrigues Silva, Johan Ruud

iScience· January 2025

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Nicotinic α7 receptors on cholinergic neurons in the striatum mediate cocaine-reinforcement, but not food reward.
Michael Fritz, Priscila Batista Rosa, Daniel Wilhelms, Maarit Jaarola, Johan Ruud

Front Mol Neurosci· January 2025

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Activation of GFRAL neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor.
Linda Engström Ruud, Ferran Font-Gironès, Joanna Zajdel, Lara Kern, Júlia Teixidor-Deulofeu, Johan Ruud

Cell Rep· April 2024

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Reduction of body weight by increased loading is associated with activation of norepinephrine neurones in the medial nucleus of the solitary tract.
Jovana Zlatkovic, Adrià Dalmau Gasull, Daniel Hägg, Ferran Font-Gironès, Jakob Bellman, Johan Ruud

J Neuroendocrinol· December 2023

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Knockout of STE20-type kinase TAOK3 does not attenuate diet-induced NAFLD development in mice.
Ying Xia, Emma Andersson, Mara Caputo, Emmelie Cansby, Francesca Sedda, Johan Ruud

Mol Med· October 2023

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The Fat Mass and Obesity-Associated Protein (FTO) Regulates Locomotor Responses to Novelty via D2R Medium Spiny Neurons.
Johan Ruud, Jens Alber, Anna Tokarska, Linda Engström Ruud, Hendrik Nolte

Cell Rep· June 2019

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Anorexia-cachexia syndrome in hepatoma tumour-bearing rats requires the area postrema but not vagal afferents and is paralleled by increased MIC-1/GDF15.
Tito Borner, Myrtha Arnold, Johan Ruud, Samuel N Breit, Wolfgang Langhans

J Cachexia Sarcopenia Muscle· June 2017

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Neuronal control of peripheral insulin sensitivity and glucose metabolism.
Johan Ruud, Sophie M Steculorum, Jens C Brüning

Nat Commun· May 2017

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Insulin-Dependent Activation of MCH Neurons Impairs Locomotor Activity and Insulin Sensitivity in Obesity.
A Christine Hausen, Johan Ruud, Hong Jiang, Simon Hess, Hristo Varbanov

Cell Rep· December 2016

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Neuroendocrinology: Electromagnetogenetic Control over Feeding and Glucose Metabolism.
Johan Ruud, Jens C Brüning

Curr Biol· June 2016

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AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue.
Sophie M Steculorum, Johan Ruud, Ismene Karakasilioti, Heiko Backes, Linda Engström Ruud

Cell· March 2016

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Metabolism: Light on leptin link to lipolysis.
Johan Ruud, Jens C Brüning

Nature· November 2015

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Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin.
Jan Mauer, Bhagirath Chaurasia, Julia Goldau, Merly C Vogt, Johan Ruud

Nat Immunol· May 2014

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Interleukin-6 primarily produced by non-hematopoietic cells mediates the lipopolysaccharide-induced febrile response.
Namik Hamzic, Yanjuan Tang, Anna Eskilsson, Unn Kugelberg, Johan Ruud

Brain Behav Immun· October 2013

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Inflammation- and tumor-induced anorexia and weight loss require MyD88 in hematopoietic/myeloid cells but not in brain endothelial or neural cells.
Johan Ruud, Daniel Björk Wilhelms, Anna Nilsson, Anna Eskilsson, Yan-Juan Tang

FASEB J· May 2013

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Cancer-induced anorexia in tumor-bearing mice is dependent on cyclooxygenase-1.
Johan Ruud, Anna Nilsson, Linda Engström Ruud, Wenhua Wang, Camilla Nilsberth

Brain Behav Immun· March 2013

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Lipopolysaccharide-induced fever depends on prostaglandin E2 production specifically in brain endothelial cells.
Linda Engström, Johan Ruud, Anna Eskilsson, Anders Larsson, Ludmila Mackerlova

Endocrinology· October 2012

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Deletion of the gene encoding MyD88 protects from anorexia in a mouse tumor model.
Johan Ruud, Fredrik Bäckhed, David Engblom, Anders Blomqvist

Brain Behav Immun· May 2010

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Long-term treatment with antidepressants, but not environmental stimulation, induces expression of NP2 mRNA in hippocampus and medial habenula.
Lisa Bjartmar, Liza Alkhori, Johan Ruud, Abdul H Mohammed, Jan Marcusson

Brain Res· April 2010

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Cyclooxygenase-1 mediates the immediate corticosterone response to peripheral immune challenge induced by lipopolysaccharide.
Louise Elander, Johan Ruud, Marina Korotkova, Per-Johan Jakobsson, Anders Blomqvist

Neurosci Lett· February 2010

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Neuron survival in vitro is more influenced by the developmental age of the cells than by glucose condition.
Arian Sepehr, Johan Ruud, Simin Mohseni

Cytotechnology· November 2009

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Inducible prostaglandin E2 synthesis interacts in a temporally supplementary sequence with constitutive prostaglandin-synthesizing enzymes in creating the hypothalamic-pituitary-adrenal axis response to immune challenge.
Louise Elander, Linda Engström, Johan Ruud, Ludmila Mackerlova, Per-Johan Jakobsson

J Neurosci· February 2009

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Identification of rat brainstem neuronal structures activated during cancer-induced anorexia.
Johan Ruud, Anders Blomqvist

J Comp Neurol· September 2007

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