Publications by authors named "Johan Spetz"

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Late apoptotic effects after treatment with Lu-octreotate in small-intestine neuroendocrine GOT1 tumor model.
Mikael Elvborn, Nishte Rassol, Daniella Pettersson, Emman Shubbar, Johan Spetz

Int J Radiat Biol· September 2025

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Early proteomic response in thyroid gland after 131I administration in female Balb/c mice.
Nils Rudqvist, Johan Spetz, Emil Schüler, Toshima Z Parris, Britta Langen

Radiat Prot Dosimetry· August 2025

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Short and long-term effects on the thyroid proteome after 131I exposure.
Klara Insulander Björk, Britta Langen, Anja Schroff, Emman Shubbar, Khalil Helou, Johan Spetz

Radiat Prot Dosimetry· August 2025

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Evaluation of coadministration schedules of rA1M for kidney protection after administration of 177Lu-octreotide.
Nishte Rassol, Charlotte Ytterbrink, Daniella Pettersson, Amin Al-Awar, Hana Bakr, Johan Spetz

Radiat Prot Dosimetry· August 2025

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Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-X degradation to overcome cancer chemoresistance.
Xingping Qin, Adam Presser, Lissah Johnson, Yusuke Matoba, Brendan S Shay, Johan Spetz

bioRxiv· June 2025

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A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma.
Veronica Rendo, Eudocia Q Lee, Connor Bossi, Nicholas Khuu, Michelle A Rudek, Johan Spetz

Sci Transl Med· February 2025

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Surgical window of opportunity trial reveals mechanisms of response and resistance to navtemadlin (KRT-232) in patients with recurrent glioblastoma.
Veronica Rendo, Eudocia Q Lee, Connor Bossi, Nicholas Khuu, Michelle A Rudek, Johan Spetz

medRxiv· August 2024

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Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX.
Rumani Singh, Stacey Yu, Marwa Osman, Zintis Inde, Cameron Fraser, Johan Spetz

Cancer Res· October 2023

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Targeting TBK1 to overcome resistance to cancer immunotherapy.
Yi Sun, Or-Yam Revach, Seth Anderson, Emily A Kessler, Clara H Wolfe, Johan K E Spetz

Nature· March 2023

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Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy-induced toxicities.
Johan K E Spetz, Mary H C Florido, Cameron S Fraser, Xingping Qin, Jonathan Choiniere

Sci Adv· November 2022

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Exploiting endogenous and therapy-induced apoptotic vulnerabilities in immunoglobulin light chain amyloidosis with BH3 mimetics.
Cameron S Fraser, Johan K E Spetz, Xingping Qin, Adam Presser, Jonathan Choiniere

Nat Commun· October 2022

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Age and sex effects across the blood proteome after ionizing radiation exposure can bias biomarker screening and risk assessment.
Britta Langen, Egor Vorontsov, Johan Spetz, John Swanpalmer, Carina Sihlbom

Sci Rep· April 2022

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Age-related long-term response in rat thyroid tissue and plasma after internal low dose exposure to I.
Malin Larsson, Nils-Petter Rudqvist, Johan Spetz, Toshima Z Parris, Britta Langen

Sci Rep· February 2022

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Correction: Long-term transcriptomic and proteomic effects in Sprague Dawley rat thyroid and plasma after internal low dose 131I exposure.
Malin Larsson, Nils Rudqvist, Johan Spetz, Emman Shubbar, Toshima Z Parris

PLoS One· October 2021

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Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity.
Zintis Inde, Ben A Croker, Clarence Yapp, Gaurav N Joshi, Johan Spetz

Sci Adv· August 2021

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Neuroblastoma xenograft models demonstrate the therapeutic potential of Lu-octreotate.
Arman Romiani, Johan Spetz, Emman Shubbar, Dan E Lind, Bengt Hallberg

BMC Cancer· August 2021

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Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics.
Veerle W Daniels, Jason J Zoeller, Nick van Gastel, Kelley E McQueeney, Salma Parvin, Johan Spetz

Sci Signal· June 2021

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Long-term transcriptomic and proteomic effects in Sprague Dawley rat thyroid and plasma after internal low dose 131I exposure.
Malin Larsson, Nils Rudqvist, Johan Spetz, Emman Shubbar, Toshima Z Parris

PLoS One· March 2021

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Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity.
Zintis Inde, Clarence Yapp, Gaurav N Joshi, Johan Spetz, Cameron Fraser

bioRxiv· September 2020

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Biodistribution of I in mice is influenced by circadian variations.
Charlotte K Andersson, Mikael Elvborn, Johan K E Spetz, Britta Langen, Eva B Forssell-Aronsson

Sci Rep· September 2020

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Increased therapeutic effect on medullary thyroid cancer using a combination of radiation and tyrosine kinase inhibitors.
Viktor Sandblom, Johan Spetz, Emman Shubbar, Mikael Montelius, Ingun Ståhl

PLoS One· August 2020

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Gemcitabine potentiates the anti-tumour effect of radiation on medullary thyroid cancer.
Viktor Sandblom, Johan Spetz, Emman Shubbar, Mikael Montelius, Ingun Ståhl

PLoS One· March 2020

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